SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tqf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 3tqf HPR(SER) KINASE
(Coxiella
burnetii) 		4 / 5 LYS A 141
LEU A 143
GLU A 132
LEU A 128
 None
 0.98A 1eta1-3tqfA:
undetectable		 1eta1-3tqfA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 3tqf HPR(SER) KINASE
(Coxiella
burnetii) 		4 / 5 LYS A 141
LEU A 143
GLU A 132
LEU A 128
 None
 1.00A 1eta2-3tqfA:
undetectable		 1eta2-3tqfA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 3tqf HPR(SER) KINASE
(Coxiella
burnetii) 		4 / 6 LYS A 141
LEU A 143
GLU A 132
LEU A 128
 None
 0.96A 1etb1-3tqfA:
undetectable		 1etb1-3tqfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 3tqf HPR(SER) KINASE
(Coxiella
burnetii) 		4 / 6 LYS A 141
LEU A 143
GLU A 132
LEU A 128
 None
 0.95A 1etb2-3tqfA:
undetectable		 1etb2-3tqfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3tqf HPR(SER) KINASE
(Coxiella
burnetii) 		4 / 8 ASP A  57
ILE A  86
GLY A  85
GLY A  39
 None
None
None
PO4  A 201 (-3.4A)
 0.63A 1me7A-3tqfA:
undetectable		 1me7A-3tqfA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 3tqf HPR(SER) KINASE
(Coxiella
burnetii) 		4 / 5 GLU A 157
LEU A 155
LEU A 154
LEU A 159
 None
 1.17A 1np1A-3tqfA:
undetectable		 1np1A-3tqfA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 3tqf HPR(SER) KINASE
(Coxiella
burnetii) 		4 / 6 LYS A 141
LEU A 143
GLU A 132
LEU A 128
 None
 0.93A 2roxB-3tqfA:
undetectable		 2roxB-3tqfA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 3tqf HPR(SER) KINASE
(Coxiella
burnetii) 		5 / 12 GLY A  79
ASN A  78
LEU A  94
PHE A  95
LEU A  97
 None
 1.01A 3p2kC-3tqfA:
undetectable		 3p2kC-3tqfA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3tqf HPR(SER) KINASE
(Coxiella
burnetii) 		4 / 8 GLU A  65
HIS A 104
GLN A  64
LEU A  62
 None
 0.92A 5w3jB-3tqfA:
undetectable		 5w3jB-3tqfA:
16.30