SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tqi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 9 LEU A 392
GLY A 237
VAL A 383
ILE A 336
GLY A 334
 None
 0.89A 1hpvA-3tqiA:
undetectable		 1hpvA-3tqiA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		4 / 8 GLY A  88
ILE A  55
LEU A  83
ASP A  14
 None
 0.92A 1jg4A-3tqiA:
2.4		 1jg4A-3tqiA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		3 / 3 THR A 185
PRO A 188
THR A 187
 None
 0.84A 1mnvD-3tqiA:
undetectable		 1mnvD-3tqiA:
2.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		4 / 5 SER A 235
PHE A 319
VAL A 285
PHE A 277
 None
 1.10A 1oipA-3tqiA:
undetectable		 1oipA-3tqiA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		4 / 7 ILE A  54
GLY A  53
PHE A  49
ASN A  50
 None
 0.82A 1oniG-3tqiA:
undetectable
1oniI-3tqiA:
undetectable		 1oniG-3tqiA:
14.90
1oniI-3tqiA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		3 / 3 THR A 185
PRO A 188
THR A 187
 None
 0.87A 1ovfB-3tqiA:
undetectable		 1ovfB-3tqiA:
2.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		4 / 4 GLY A 236
SER A 240
VAL A 273
LEU A 265
 None
 1.33A 1yajB-3tqiA:
2.5		 1yajB-3tqiA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_B_GBNB914_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 10 PHE A 319
GLY A 236
THR A 243
ALA A 244
ALA A 241
 None
 1.16A 2ej3B-3tqiA:
undetectable		 2ej3B-3tqiA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		4 / 6 ASP A 145
SER A 142
SER A  17
GLY A  59
 None
 1.03A 2j2pA-3tqiA:
undetectable
2j2pC-3tqiA:
undetectable		 2j2pA-3tqiA:
19.19
2j2pC-3tqiA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		4 / 9 ILE A  10
ALA A 195
VAL A 198
CYH A 204
 None
 1.00A 2vufB-3tqiA:
undetectable		 2vufB-3tqiA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 LEU A 246
GLY A 332
SER A 217
LEU A 375
LEU A 378
 None
 1.10A 2zbpA-3tqiA:
3.3		 2zbpA-3tqiA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		3 / 3 LYS A 224
ILE A 336
PHE A 379
 None
 0.94A 3j7zS-3tqiA:
undetectable
3j7za-3tqiA:
undetectable		 3j7zS-3tqiA:
11.70
3j7za-3tqiA:
3.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		4 / 7 VAL A  82
ILE A  46
MET A  92
ARG A  28
 None
 1.20A 3ms9B-3tqiA:
undetectable		 3ms9B-3tqiA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 PHE A 176
ALA A 167
LEU A 121
LEU A  83
THR A 157
 None
 1.08A 3nrrA-3tqiA:
undetectable		 3nrrA-3tqiA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		4 / 7 ARG A  26
ILE A  23
LEU A 178
ARG A 192
 None
 0.99A 3nxuA-3tqiA:
undetectable		 3nxuA-3tqiA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 9 PHE A 122
PHE A 180
ILE A 193
GLY A 190
THR A 187
 None
 1.40A 3t3rC-3tqiA:
undetectable		 3t3rC-3tqiA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 9 LEU A 234
PHE A 277
THR A 245
VAL A 247
LEU A 255
 None
 1.47A 3uncA-3tqiA:
undetectable		 3uncA-3tqiA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 9 LEU A 234
PHE A 277
THR A 245
VAL A 247
LEU A 255
 None
 1.46A 3uncB-3tqiA:
1.2		 3uncB-3tqiA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		3 / 3 LEU A 178
MET A 141
ASP A 138
 None
 0.87A 3v5wA-3tqiA:
undetectable		 3v5wA-3tqiA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		4 / 4 LEU A 178
ILE A  55
GLY A 177
PHE A 197
 None
 1.04A 4dc3A-3tqiA:
undetectable		 4dc3A-3tqiA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 5 PHE A 122
PHE A 180
ILE A 193
GLY A 190
THR A 187
 None
 1.35A 4ejjC-3tqiA:
undetectable		 4ejjC-3tqiA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 LEU A 116
GLY A 190
PHE A 122
THR A 157
THR A 187
 None
 1.40A 4mubA-3tqiA:
2.0		 4mubA-3tqiA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 LEU A 390
GLY A 387
THR A 210
ILE A 213
LEU A 378
 None
 1.15A 4o5fA-3tqiA:
undetectable
4o5fB-3tqiA:
undetectable		 4o5fA-3tqiA:
21.94
4o5fB-3tqiA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 LEU A 378
LEU A 390
GLY A 387
THR A 210
ILE A 213
 None
 1.19A 4o5fA-3tqiA:
undetectable
4o5fB-3tqiA:
undetectable		 4o5fA-3tqiA:
21.94
4o5fB-3tqiA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 11 GLY A 263
LEU A 265
PHE A 294
LEU A 298
ALA A 311
 None
 0.88A 4wnuA-3tqiA:
undetectable		 4wnuA-3tqiA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		3 / 3 LEU A 386
VAL A 238
ASP A 239
 None
 0.54A 4y8wC-3tqiA:
undetectable		 4y8wC-3tqiA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		3 / 3 LEU A 390
VAL A 238
ASP A 239
 None
 0.65A 4y8wC-3tqiA:
undetectable		 4y8wC-3tqiA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		3 / 3 VAL A 340
THR A 335
ARG A 376
 None
 0.49A 5b2sB-3tqiA:
undetectable		 5b2sB-3tqiA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		3 / 3 VAL A 340
THR A 335
ARG A 376
 None
 0.45A 5b2tB-3tqiA:
2.8		 5b2tB-3tqiA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 LEU A 390
GLY A 387
THR A 210
ILE A 213
LEU A 378
 None
 1.16A 5b8hA-3tqiA:
undetectable
5b8hB-3tqiA:
undetectable		 5b8hA-3tqiA:
20.38
5b8hB-3tqiA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 LEU A 378
LEU A 390
GLY A 387
THR A 210
ILE A 213
 None
 1.14A 5b8hA-3tqiA:
undetectable
5b8hB-3tqiA:
undetectable		 5b8hA-3tqiA:
20.38
5b8hB-3tqiA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHN_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  88
PHE A 122
PHE A 180
GLN A 179
 None
 1.19A 5jhnB-3tqiA:
undetectable		 5jhnB-3tqiA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JIN_A_SAMA1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  88
PHE A 122
PHE A 180
GLN A 179
 None
 1.20A 5jinA-3tqiA:
undetectable		 5jinA-3tqiA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JJ0_A_SAMA1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  88
PHE A 122
PHE A 180
GLN A 179
 None
 1.16A 5jj0A-3tqiA:
undetectable		 5jj0A-3tqiA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JJ0_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  88
PHE A 122
PHE A 180
GLN A 179
 None
 1.20A 5jj0B-3tqiA:
undetectable		 5jj0B-3tqiA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T0K_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  84
PHE A 122
PHE A 180
GLN A 179
 None
 1.38A 5t0kA-3tqiA:
undetectable		 5t0kA-3tqiA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T0K_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  88
PHE A 122
PHE A 180
GLN A 179
 None
 1.21A 5t0kA-3tqiA:
undetectable		 5t0kA-3tqiA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T0K_B_SAMB1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  84
PHE A 122
PHE A 180
GLN A 179
 None
 1.42A 5t0kB-3tqiA:
undetectable		 5t0kB-3tqiA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T0K_B_SAMB1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  88
PHE A 122
PHE A 180
GLN A 179
 None
 1.22A 5t0kB-3tqiA:
undetectable		 5t0kB-3tqiA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T0M_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  84
PHE A 122
PHE A 180
GLN A 179
 None
 1.45A 5t0mB-3tqiA:
undetectable		 5t0mB-3tqiA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T0M_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  88
PHE A 122
PHE A 180
GLN A 179
 None
 1.25A 5t0mB-3tqiA:
undetectable		 5t0mB-3tqiA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TTF_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  84
PHE A 122
PHE A 180
GLN A 179
 None
 1.38A 5ttfB-3tqiA:
undetectable		 5ttfB-3tqiA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TTF_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  88
PHE A 122
PHE A 180
GLN A 179
 None
 1.16A 5ttfB-3tqiA:
undetectable		 5ttfB-3tqiA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUY_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  84
PHE A 122
PHE A 180
GLN A 179
 None
 1.39A 5tuyA-3tqiA:
undetectable		 5tuyA-3tqiA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUY_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  88
PHE A 122
PHE A 180
GLN A 179
 None
 1.18A 5tuyA-3tqiA:
undetectable		 5tuyA-3tqiA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUY_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  84
PHE A 122
PHE A 180
GLN A 179
 None
 1.41A 5tuyB-3tqiA:
undetectable		 5tuyB-3tqiA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUY_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  88
PHE A 122
PHE A 180
GLN A 179
 None
 1.20A 5tuyB-3tqiA:
undetectable		 5tuyB-3tqiA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V9I_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  84
PHE A 122
PHE A 180
GLN A 179
 None
 1.37A 5v9iA-3tqiA:
undetectable		 5v9iA-3tqiA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V9I_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  88
PHE A 122
PHE A 180
GLN A 179
 None
 1.14A 5v9iA-3tqiA:
undetectable		 5v9iA-3tqiA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		4 / 7 GLN A 254
GLY A 226
ILE A 221
TRP A 330
 None
 1.16A 5vlmC-3tqiA:
undetectable		 5vlmC-3tqiA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSC_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  84
PHE A 122
PHE A 180
GLN A 179
 None
 1.41A 5vscA-3tqiA:
undetectable		 5vscA-3tqiA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSC_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  84
PHE A 122
PHE A 180
GLN A 179
 None
 1.40A 5vscB-3tqiA:
undetectable		 5vscB-3tqiA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSE_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  84
PHE A 122
PHE A 180
GLN A 179
 None
 1.43A 5vseA-3tqiA:
undetectable		 5vseA-3tqiA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSE_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 MET A  89
GLY A  84
PHE A 122
PHE A 180
GLN A 179
 None
 1.41A 5vseB-3tqiA:
undetectable		 5vseB-3tqiA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		4 / 8 GLU A 342
SER A 240
PHE A 315
LEU A 265
 None
 1.07A 5y2tB-3tqiA:
undetectable		 5y2tB-3tqiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		4 / 6 PHE A  15
GLY A  88
THR A  91
GLN A  95
 None
 1.10A 6ag0A-3tqiA:
undetectable		 6ag0A-3tqiA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		5 / 12 VAL A 318
PHE A 294
LEU A 274
VAL A 273
GLY A 263
 None
 1.42A 6brdA-3tqiA:
undetectable		 6brdA-3tqiA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		4 / 7 ILE A  23
VAL A  27
PRO A 182
ILE A  10
 None
 0.89A 6cduF-3tqiA:
undetectable
6cduG-3tqiA:
undetectable		 6cduF-3tqiA:
20.79
6cduG-3tqiA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]
(Coxiella
burnetii) 		4 / 8 ILE A  23
VAL A  27
PRO A 182
ILE A  10
 None
 0.94A 6cduG-3tqiA:
undetectable
6cduH-3tqiA:
undetectable		 6cduG-3tqiA:
20.79
6cduH-3tqiA:
20.79