SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tqo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 9 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.25A 1c9sS-3tqoA:
undetectable
1c9sT-3tqoA:
undetectable
1c9sS-3tqoA:
10.75
1c9sT-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 4 ARG A 341
ALA A 345
ALA A 357
GLU A 361
None
1.15A 1e7bA-3tqoA:
undetectable
1e7bA-3tqoA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 4 ARG A 341
ALA A 345
ALA A 357
GLU A 361
None
1.12A 1e7bB-3tqoA:
2.4
1e7bB-3tqoA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 9 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 1gtfO-3tqoA:
undetectable
1gtfP-3tqoA:
undetectable
1gtfO-3tqoA:
10.75
1gtfP-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 1gtfP-3tqoA:
undetectable
1gtfQ-3tqoA:
undetectable
1gtfP-3tqoA:
10.75
1gtfQ-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.21A 1gtfT-3tqoA:
undetectable
1gtfU-3tqoA:
undetectable
1gtfT-3tqoA:
10.75
1gtfU-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 11 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.21A 1gtfU-3tqoA:
undetectable
1gtfV-3tqoA:
undetectable
1gtfU-3tqoA:
10.75
1gtfV-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 SER A 214
HIS A 235
ALA A 212
HIS A 236
ILE A 208
None
ZN  A 461 (-3.4A)
None
None
None
1.21A 1gtfL-3tqoA:
undetectable
1gtfV-3tqoA:
undetectable
1gtfL-3tqoA:
10.75
1gtfV-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 11 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.15A 1gtnM-3tqoA:
undetectable
1gtnN-3tqoA:
undetectable
1gtnM-3tqoA:
10.75
1gtnN-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.17A 1gtnN-3tqoA:
undetectable
1gtnO-3tqoA:
undetectable
1gtnN-3tqoA:
10.75
1gtnO-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 9 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.21A 1gtnR-3tqoA:
undetectable
1gtnS-3tqoA:
undetectable
1gtnR-3tqoA:
10.75
1gtnS-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.20A 1gtnU-3tqoA:
undetectable
1gtnV-3tqoA:
undetectable
1gtnU-3tqoA:
10.75
1gtnV-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 11 GLY A  30
HIS A  38
HIS A  41
GLY A 228
LEU A 260
None
0.94A 1jzsA-3tqoA:
5.9
1jzsA-3tqoA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
3 / 3 GLU A 239
HIS A 236
HIS A 235
ZN  A 461 (-4.2A)
None
ZN  A 461 (-3.4A)
0.71A 1oe2A-3tqoA:
undetectable
1oe2A-3tqoA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 11 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.23A 1utdM-3tqoA:
undetectable
1utdN-3tqoA:
undetectable
1utdM-3tqoA:
10.75
1utdN-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.26A 1utdQ-3tqoA:
undetectable
1utdR-3tqoA:
undetectable
1utdQ-3tqoA:
10.75
1utdR-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.20A 1utdR-3tqoA:
undetectable
1utdS-3tqoA:
undetectable
1utdR-3tqoA:
10.75
1utdS-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.17A 1utdT-3tqoA:
undetectable
1utdU-3tqoA:
undetectable
1utdT-3tqoA:
10.75
1utdU-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.20A 1utdU-3tqoA:
undetectable
1utdV-3tqoA:
undetectable
1utdU-3tqoA:
10.75
1utdV-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 12 HIS A 298
ALA A 258
LEU A 261
GLY A 226
PHE A  48
None
1.08A 2f8lA-3tqoA:
2.1
2f8lA-3tqoA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 12 HIS A  38
GLY A  40
HIS A  41
ASP A 230
LEU A 261
None
0.95A 2x1lB-3tqoA:
28.0
2x1lB-3tqoA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 12 HIS A  38
GLY A  40
HIS A  41
GLY A 228
LEU A 261
None
0.75A 2x1lB-3tqoA:
28.0
2x1lB-3tqoA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 6 HIS A 235
ASP A  70
THR A  69
HIS A 225
ZN  A 461 (-3.4A)
None
None
None
1.43A 3ag1A-3tqoA:
undetectable
3ag1C-3tqoA:
undetectable
3ag1A-3tqoA:
20.14
3ag1C-3tqoA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 7 HIS A 235
ASP A  70
THR A  69
HIS A 225
ZN  A 461 (-3.4A)
None
None
None
1.43A 3ag4N-3tqoA:
undetectable
3ag4P-3tqoA:
undetectable
3ag4N-3tqoA:
20.14
3ag4P-3tqoA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 ALA A 281
LEU A 294
LEU A 290
ARG A 314
LEU A 261
None
1.47A 3erdB-3tqoA:
undetectable
3erdB-3tqoA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
3 / 3 TYR A  54
GLU A 384
TYR A 338
None
0.82A 3ug8A-3tqoA:
undetectable
3ug8A-3tqoA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 12 SER A 285
LEU A 282
ILE A 263
ILE A  39
LEU A 294
None
1.26A 3w67D-3tqoA:
undetectable
3w67D-3tqoA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 5 HIS A 207
HIS A 225
GLU A 239
HIS A 236
None
None
ZN  A 461 (-4.2A)
None
1.18A 4a7bB-3tqoA:
undetectable
4a7bB-3tqoA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 5 GLY A 205
ILE A 208
TRP A 185
VAL A 143
None
1.22A 4d33A-3tqoA:
undetectable
4d33A-3tqoA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 5 GLY A 205
ILE A 208
TRP A 185
VAL A 143
None
1.23A 4d33B-3tqoA:
undetectable
4d33B-3tqoA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DMG_A_SAMA401_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 12 TYR A 134
ASP A 131
GLU A 248
ALA A 245
ASP A 146
None
1.19A 4dmgA-3tqoA:
undetectable
4dmgA-3tqoA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 4 ASN A 390
GLY A 393
ASP A 349
ASP A  49
None
1.33A 4n49A-3tqoA:
undetectable
4n49A-3tqoA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.17A 5eeuN-3tqoA:
undetectable
5eeuO-3tqoA:
undetectable
5eeuN-3tqoA:
10.75
5eeuO-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.21A 5eeuP-3tqoA:
undetectable
5eeuQ-3tqoA:
undetectable
5eeuP-3tqoA:
10.75
5eeuQ-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5eeuR-3tqoA:
undetectable
5eeuS-3tqoA:
undetectable
5eeuR-3tqoA:
10.75
5eeuS-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5eeuS-3tqoA:
undetectable
5eeuT-3tqoA:
undetectable
5eeuS-3tqoA:
10.75
5eeuT-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.24A 5eeuT-3tqoA:
undetectable
5eeuU-3tqoA:
undetectable
5eeuT-3tqoA:
10.75
5eeuU-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5eeuU-3tqoA:
undetectable
5eeuV-3tqoA:
undetectable
5eeuU-3tqoA:
10.75
5eeuV-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.18A 5eevN-3tqoA:
undetectable
5eevO-3tqoA:
undetectable
5eevN-3tqoA:
10.75
5eevO-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.21A 5eevP-3tqoA:
undetectable
5eevQ-3tqoA:
undetectable
5eevP-3tqoA:
10.75
5eevQ-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.23A 5eevR-3tqoA:
undetectable
5eevS-3tqoA:
undetectable
5eevR-3tqoA:
10.75
5eevS-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5eevS-3tqoA:
undetectable
5eevT-3tqoA:
undetectable
5eevS-3tqoA:
10.75
5eevT-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.24A 5eevT-3tqoA:
undetectable
5eevU-3tqoA:
undetectable
5eevT-3tqoA:
10.75
5eevU-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.23A 5eevU-3tqoA:
undetectable
5eevV-3tqoA:
undetectable
5eevU-3tqoA:
10.75
5eevV-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.18A 5eewN-3tqoA:
undetectable
5eewO-3tqoA:
undetectable
5eewN-3tqoA:
10.75
5eewO-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5eewP-3tqoA:
undetectable
5eewQ-3tqoA:
undetectable
5eewP-3tqoA:
10.75
5eewQ-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5eewR-3tqoA:
undetectable
5eewS-3tqoA:
undetectable
5eewR-3tqoA:
10.75
5eewS-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5eewS-3tqoA:
undetectable
5eewT-3tqoA:
undetectable
5eewS-3tqoA:
10.75
5eewT-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.24A 5eewT-3tqoA:
undetectable
5eewU-3tqoA:
undetectable
5eewT-3tqoA:
10.75
5eewU-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.23A 5eewU-3tqoA:
undetectable
5eewV-3tqoA:
undetectable
5eewU-3tqoA:
10.75
5eewV-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.18A 5eexN-3tqoA:
undetectable
5eexO-3tqoA:
undetectable
5eexN-3tqoA:
10.75
5eexO-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.21A 5eexP-3tqoA:
undetectable
5eexQ-3tqoA:
undetectable
5eexP-3tqoA:
10.75
5eexQ-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5eexR-3tqoA:
undetectable
5eexS-3tqoA:
undetectable
5eexR-3tqoA:
10.75
5eexS-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5eexS-3tqoA:
undetectable
5eexT-3tqoA:
undetectable
5eexS-3tqoA:
10.75
5eexT-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.24A 5eexT-3tqoA:
undetectable
5eexU-3tqoA:
undetectable
5eexT-3tqoA:
10.75
5eexU-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5eexU-3tqoA:
undetectable
5eexV-3tqoA:
undetectable
5eexU-3tqoA:
10.75
5eexV-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.18A 5eeyN-3tqoA:
undetectable
5eeyO-3tqoA:
undetectable
5eeyN-3tqoA:
10.75
5eeyO-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.21A 5eeyP-3tqoA:
undetectable
5eeyQ-3tqoA:
undetectable
5eeyP-3tqoA:
10.75
5eeyQ-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5eeyR-3tqoA:
undetectable
5eeyS-3tqoA:
undetectable
5eeyR-3tqoA:
10.75
5eeyS-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5eeyS-3tqoA:
undetectable
5eeyT-3tqoA:
undetectable
5eeyS-3tqoA:
10.75
5eeyT-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.24A 5eeyT-3tqoA:
undetectable
5eeyU-3tqoA:
undetectable
5eeyT-3tqoA:
10.75
5eeyU-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.23A 5eeyU-3tqoA:
undetectable
5eeyV-3tqoA:
undetectable
5eeyU-3tqoA:
10.75
5eeyV-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.18A 5eezN-3tqoA:
undetectable
5eezO-3tqoA:
undetectable
5eezN-3tqoA:
10.75
5eezO-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.21A 5eezP-3tqoA:
undetectable
5eezQ-3tqoA:
undetectable
5eezP-3tqoA:
10.75
5eezQ-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5eezR-3tqoA:
undetectable
5eezS-3tqoA:
undetectable
5eezR-3tqoA:
10.75
5eezS-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5eezS-3tqoA:
undetectable
5eezT-3tqoA:
undetectable
5eezS-3tqoA:
10.75
5eezT-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.25A 5eezT-3tqoA:
undetectable
5eezU-3tqoA:
undetectable
5eezT-3tqoA:
10.75
5eezU-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.23A 5eezU-3tqoA:
undetectable
5eezV-3tqoA:
undetectable
5eezU-3tqoA:
10.75
5eezV-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.18A 5ef0N-3tqoA:
undetectable
5ef0O-3tqoA:
undetectable
5ef0N-3tqoA:
10.75
5ef0O-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.21A 5ef0P-3tqoA:
undetectable
5ef0Q-3tqoA:
undetectable
5ef0P-3tqoA:
10.75
5ef0Q-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5ef0R-3tqoA:
undetectable
5ef0S-3tqoA:
undetectable
5ef0R-3tqoA:
10.75
5ef0S-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5ef0S-3tqoA:
undetectable
5ef0T-3tqoA:
undetectable
5ef0S-3tqoA:
10.75
5ef0T-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.25A 5ef0T-3tqoA:
undetectable
5ef0U-3tqoA:
undetectable
5ef0T-3tqoA:
10.75
5ef0U-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.23A 5ef0U-3tqoA:
undetectable
5ef0V-3tqoA:
undetectable
5ef0U-3tqoA:
10.75
5ef0V-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.18A 5ef1N-3tqoA:
undetectable
5ef1O-3tqoA:
undetectable
5ef1N-3tqoA:
10.75
5ef1O-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.21A 5ef1P-3tqoA:
undetectable
5ef1Q-3tqoA:
undetectable
5ef1P-3tqoA:
10.75
5ef1Q-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5ef1R-3tqoA:
undetectable
5ef1S-3tqoA:
undetectable
5ef1R-3tqoA:
10.75
5ef1S-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5ef1S-3tqoA:
undetectable
5ef1T-3tqoA:
undetectable
5ef1S-3tqoA:
10.75
5ef1T-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.24A 5ef1T-3tqoA:
undetectable
5ef1U-3tqoA:
undetectable
5ef1T-3tqoA:
10.75
5ef1U-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5ef1U-3tqoA:
undetectable
5ef1V-3tqoA:
undetectable
5ef1U-3tqoA:
10.75
5ef1V-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.18A 5ef2N-3tqoA:
undetectable
5ef2O-3tqoA:
undetectable
5ef2N-3tqoA:
10.75
5ef2O-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.21A 5ef2P-3tqoA:
undetectable
5ef2Q-3tqoA:
undetectable
5ef2P-3tqoA:
10.75
5ef2Q-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5ef2R-3tqoA:
undetectable
5ef2S-3tqoA:
undetectable
5ef2R-3tqoA:
10.75
5ef2S-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5ef2S-3tqoA:
undetectable
5ef2T-3tqoA:
undetectable
5ef2S-3tqoA:
10.75
5ef2T-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.24A 5ef2T-3tqoA:
undetectable
5ef2U-3tqoA:
undetectable
5ef2T-3tqoA:
10.75
5ef2U-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5ef2U-3tqoA:
undetectable
5ef2V-3tqoA:
undetectable
5ef2U-3tqoA:
10.75
5ef2V-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.17A 5ef3N-3tqoA:
undetectable
5ef3O-3tqoA:
undetectable
5ef3N-3tqoA:
10.75
5ef3O-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.21A 5ef3P-3tqoA:
undetectable
5ef3Q-3tqoA:
undetectable
5ef3P-3tqoA:
10.75
5ef3Q-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5ef3R-3tqoA:
undetectable
5ef3S-3tqoA:
undetectable
5ef3R-3tqoA:
10.75
5ef3S-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5ef3S-3tqoA:
undetectable
5ef3T-3tqoA:
undetectable
5ef3S-3tqoA:
10.75
5ef3T-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.25A 5ef3T-3tqoA:
undetectable
5ef3U-3tqoA:
undetectable
5ef3T-3tqoA:
10.75
5ef3U-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 10 HIS A 235
ALA A 212
HIS A 236
ILE A 208
SER A 214
ZN  A 461 (-3.4A)
None
None
None
None
1.22A 5ef3U-3tqoA:
undetectable
5ef3V-3tqoA:
undetectable
5ef3U-3tqoA:
10.75
5ef3V-3tqoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 12 PHE A  48
ILE A  47
TYR A 299
GLY A 228
HIS A 158
None
1.22A 5esgA-3tqoA:
undetectable
5esgA-3tqoA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 12 PHE A  48
ILE A  47
TYR A 299
GLY A 228
HIS A 158
None
1.20A 5eslA-3tqoA:
undetectable
5eslA-3tqoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 12 HIS A  38
GLY A  40
HIS A  41
TYR A  34
GLY A 228
None
0.91A 5hg0B-3tqoA:
5.4
5hg0B-3tqoA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 6 PHE A  48
VAL A  51
ILE A   5
ASP A 349
None
0.97A 5iwuA-3tqoA:
undetectable
5iwuA-3tqoA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 11 ASN A  -1
VAL A   3
SER A   2
TYR A  60
LEU A  55
None
1.19A 5jh7B-3tqoA:
undetectable
5jh7B-3tqoA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 11 ASN A  -1
VAL A   3
SER A   2
TYR A  60
LEU A  55
None
1.17A 5jh7D-3tqoA:
undetectable
5jh7D-3tqoA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 12 PHE A  48
ILE A  47
TYR A 299
GLY A 228
HIS A 158
None
1.15A 5jlcA-3tqoA:
undetectable
5jlcA-3tqoA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 12 PHE A 150
TYR A 153
LEU A 129
ALA A 245
LEU A 156
None
1.36A 5ljbA-3tqoA:
undetectable
5ljbA-3tqoA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 8 SER A   8
HIS A 236
HIS A 225
VAL A  28
None
1.00A 5m8rB-3tqoA:
undetectable
5m8rB-3tqoA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 12 PHE A  48
ILE A  47
TYR A 299
GLY A 228
HIS A 158
None
1.33A 5v5zA-3tqoA:
undetectable
5v5zA-3tqoA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 9 TYR A 118
ILE A 122
ILE A 126
LEU A 129
None
0.74A 5vkqB-3tqoA:
undetectable
5vkqC-3tqoA:
undetectable
5vkqB-3tqoA:
14.63
5vkqC-3tqoA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
3 / 3 GLU A 101
LEU A 104
ARG A 291
None
0.69A 6d8fA-3tqoA:
3.0
6d8fA-3tqoA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
3 / 3 HIS A  98
ARG A 114
ILE A  94
None
0.85A 6fgdA-3tqoA:
2.8
6fgdA-3tqoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
3 / 3 TRP A 195
ILE A  71
GLU A 192
None
0.78A 6hcxA-3tqoA:
undetectable
6hcxA-3tqoA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
5 / 12 VAL A  65
ILE A 208
ILE A 217
PHE A 222
PHE A 251
None
1.40A 6j20A-3tqoA:
undetectable
6j20A-3tqoA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 7 ARG A 114
ALA A 115
ILE A  94
ALA A  90
None
0.96A 6ma7A-3tqoA:
undetectable
6ma7A-3tqoA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 4 ASP A  35
ILE A  75
PRO A  86
LEU A  89
None
1.27A 6mkeB-3tqoA:
undetectable
6mkeB-3tqoA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 4 ASP A  35
ILE A  75
PRO A  86
LEU A  89
None
1.31A 6mkeA-3tqoA:
undetectable
6mkeA-3tqoA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))
3tqo CYSTEINYL-TRNA
SYNTHETASE

(Coxiella
burnetii)
4 / 7 GLY A 297
ASN A 309
GLU A 311
GLY A 313
None
0.84A 6n7fA-3tqoA:
undetectable
6n7fA-3tqoA:
9.31