SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tqq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 3tqq METHIONYL-TRNA
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 7 PHE A 258
SER A 272
ALA A 274
ILE A 279
 None
 0.99A 1fxhA-3tqqA:
undetectable
1fxhB-3tqqA:
undetectable		 1fxhA-3tqqA:
19.38
1fxhB-3tqqA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 3tqq METHIONYL-TRNA
FORMYLTRANSFERASE
(Coxiella
burnetii) 		3 / 3 ASN A 107
PHE A   7
VAL A  87
 None
 0.87A 1kijA-3tqqA:
undetectable		 1kijA-3tqqA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 3tqq METHIONYL-TRNA
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 8 PHE A 258
SER A 272
ALA A 274
ILE A 279
 None
 1.05A 1pnlA-3tqqA:
undetectable
1pnlB-3tqqA:
undetectable		 1pnlA-3tqqA:
19.38
1pnlB-3tqqA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 3tqq METHIONYL-TRNA
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 11 TRP A 215
ILE A 273
LEU A 263
LEU A 306
MET A 244
 None
 1.19A 2a15A-3tqqA:
undetectable		 2a15A-3tqqA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 3tqq METHIONYL-TRNA
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 12 PHE A 298
GLY A 270
HIS A 283
ASP A 265
PHE A 239
 None
 1.48A 3a25A-3tqqA:
undetectable		 3a25A-3tqqA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 3tqq METHIONYL-TRNA
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 6 ILE A 273
MET A 244
ILE A 246
HIS A 283
 None
 1.06A 3eteA-3tqqA:
3.0
3eteE-3tqqA:
3.3		 3eteA-3tqqA:
21.27
3eteE-3tqqA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 3tqq METHIONYL-TRNA
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 5 ILE A 273
MET A 244
ILE A 246
HIS A 283
 None
 1.05A 3eteB-3tqqA:
3.1
3eteC-3tqqA:
3.1		 3eteB-3tqqA:
21.27
3eteC-3tqqA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 3tqq METHIONYL-TRNA
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 7 MET A 244
ILE A 246
HIS A 283
ILE A 273
 None
 1.07A 3eteD-3tqqA:
3.1
3eteF-3tqqA:
3.1		 3eteD-3tqqA:
21.27
3eteF-3tqqA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3tqq METHIONYL-TRNA
FORMYLTRANSFERASE
(Coxiella
burnetii) 		3 / 3 ASP A  82
ARG A  27
LYS A   4
 None
 1.22A 3wipG-3tqqA:
undetectable		 3wipG-3tqqA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 3tqq METHIONYL-TRNA
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 6 LEU A 306
MET A 244
LEU A 282
VAL A 252
 None
 1.15A 4okbA-3tqqA:
undetectable		 4okbA-3tqqA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3tqq METHIONYL-TRNA
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 8 THR A 237
LEU A 280
VAL A 264
LEU A 263
 None
 0.79A 4r38A-3tqqA:
undetectable		 4r38A-3tqqA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3tqq METHIONYL-TRNA
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 7 ASN A  99
LYS A  96
TYR A  32
PHE A   7
 None
 1.17A 4yv5B-3tqqA:
undetectable		 4yv5B-3tqqA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3tqq METHIONYL-TRNA
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 8 SER A  24
HIS A  26
LEU A 179
LEU A 178
 K  A 315 (-4.5A)
None
None
None
 1.20A 5dzkd-3tqqA:
undetectable
5dzkr-3tqqA:
undetectable		 5dzkd-3tqqA:
23.20
5dzkr-3tqqA:
1.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3tqq METHIONYL-TRNA
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 6 SER A  24
HIS A  26
LEU A 179
LEU A 178
 K  A 315 (-4.5A)
None
None
None
 1.22A 5dzke-3tqqA:
undetectable
5dzks-3tqqA:
undetectable		 5dzke-3tqqA:
23.20
5dzks-3tqqA:
1.77