SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tqr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 11 LEU A 207
VAL A 200
ILE A 109
VAL A 184
PHE A 188
 None
 1.35A 1gx9A-3tqrA:
undetectable		 1gx9A-3tqrA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 8 ILE A  79
LEU A  75
PHE A  92
MET A  93
 None
 1.08A 1os6A-3tqrA:
undetectable		 1os6A-3tqrA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 12 ILE A 111
ILE A 180
VAL A 184
PHE A 188
LEU A  86
 None
 1.00A 1uduB-3tqrA:
undetectable		 1uduB-3tqrA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 12 ILE A 111
ILE A 180
VAL A 184
PHE A 188
LEU A  86
 None
 0.89A 1xozA-3tqrA:
undetectable		 1xozA-3tqrA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_3
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 12 ILE A  55
GLY A  14
ASN A  40
LEU A  75
VAL A  88
 None
 1.28A 2nyrB-3tqrA:
4.0		 2nyrB-3tqrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 12 LEU A  19
ALA A  44
ASP A  43
VAL A  10
ILE A  12
 None
 1.15A 2o4lA-3tqrA:
undetectable		 2o4lA-3tqrA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 12 ALA A  44
GLY A  91
THR A  57
VAL A  37
ASN A  15
 None
 0.99A 2okcA-3tqrA:
2.5		 2okcA-3tqrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 10 VAL A 140
ILE A 153
LEU A   6
LEU A 193
ALA A 189
 None
 1.22A 2xf3A-3tqrA:
undetectable		 2xf3A-3tqrA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 6 SER A  13
PHE A  92
PHE A  71
HIS A  62
 None
 1.43A 3lskB-3tqrA:
3.7		 3lskB-3tqrA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 6 SER A  13
PHE A  92
PHE A  71
HIS A  62
 None
 1.42A 3lskD-3tqrA:
1.6		 3lskD-3tqrA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 12 VAL A 143
MET A 108
LEU A  89
ILE A  60
PHE A  71
 None
 1.27A 3mnoA-3tqrA:
undetectable		 3mnoA-3tqrA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 12 VAL A 143
MET A 108
LEU A  89
ILE A  60
PHE A  71
 None
 1.28A 3mnpA-3tqrA:
undetectable		 3mnpA-3tqrA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 6 SER A 210
LEU A 116
HIS A 112
ARG A 157
 None
 1.31A 3thrB-3tqrA:
undetectable		 3thrB-3tqrA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		3 / 3 PHE A 214
CYH A 154
HIS A 212
 None
 0.98A 3u9fF-3tqrA:
undetectable		 3u9fF-3tqrA:
25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		3 / 3 PHE A 214
CYH A 154
HIS A 212
 None
 1.04A 3u9fG-3tqrA:
undetectable		 3u9fG-3tqrA:
25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		3 / 3 PHE A 214
CYH A 154
HIS A 212
 None
 1.06A 3u9fL-3tqrA:
undetectable		 3u9fL-3tqrA:
25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		3 / 3 PHE A 214
CYH A 154
HIS A 212
 None
 1.09A 3u9fS-3tqrA:
undetectable		 3u9fS-3tqrA:
25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 12 GLU A 177
ILE A 111
LEU A  89
GLY A  91
VAL A  88
 None
 1.06A 4fqsA-3tqrA:
undetectable		 4fqsA-3tqrA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 12 GLU A 177
ILE A 111
LEU A  89
GLY A  91
VAL A  88
 None
 1.07A 4fqsB-3tqrA:
undetectable		 4fqsB-3tqrA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 12 LEU A  19
VAL A  10
LEU A   6
ILE A  34
ILE A  23
 None
 1.01A 4ltwA-3tqrA:
undetectable		 4ltwA-3tqrA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 7 THR A 120
TYR A 119
THR A 124
SER A 114
 None
 1.26A 5b6iA-3tqrA:
1.8		 5b6iA-3tqrA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_B_ADNB302_1
(FLUORINASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		4 / 6 THR A 120
TYR A 119
THR A 124
SER A 114
 None
 1.25A 5b6iB-3tqrA:
2.2		 5b6iB-3tqrA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Coxiella
burnetii) 		5 / 12 LEU A 158
GLY A 137
HIS A 136
VAL A 184
VAL A 140
 None
 1.28A 6bxlB-3tqrA:
1.8		 6bxlB-3tqrA:
19.84