SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tqs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 9 LEU A  21
ILE A  24
VAL A 104
GLY A 105
LEU A  50
None
1.25A 1e7aB-3tqsA:
undetectable
1e7aB-3tqsA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 11 GLY A  40
GLY A  42
GLU A  61
LEU A  66
ASP A  86
None
0.95A 1jg3A-3tqsA:
9.6
1jg3A-3tqsA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 11 GLY A  40
GLY A  42
GLU A  61
LEU A  66
LEU A 107
None
0.95A 1jg3A-3tqsA:
9.6
1jg3A-3tqsA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 11 GLY A  40
GLY A  42
GLU A  61
LEU A  66
ASP A  86
None
0.92A 1jg3B-3tqsA:
9.7
1jg3B-3tqsA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 11 GLY A  40
GLY A  42
GLU A  61
LEU A  66
LEU A 107
None
0.96A 1jg3B-3tqsA:
9.7
1jg3B-3tqsA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
4 / 8 GLU A  38
GLY A  40
GLU A  61
LEU A  66
None
0.62A 1jg4A-3tqsA:
9.7
1jg4A-3tqsA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
4 / 7 PHE A 250
ALA A 210
ILE A 236
ILE A 226
None
0.91A 1oniD-3tqsA:
undetectable
1oniF-3tqsA:
undetectable
1oniD-3tqsA:
20.65
1oniF-3tqsA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
10 / 12 PHE A  14
GLU A  38
GLY A  40
GLY A  42
ASP A  63
LEU A  66
ASP A  86
ASN A 106
PRO A 108
ILE A 111
None
0.92A 1qaoA-3tqsA:
23.5
1qaoA-3tqsA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
10 / 12 PHE A  14
GLU A  38
GLY A  40
ILE A  62
ASP A  63
LEU A  66
ASP A  86
ASN A 106
PRO A 108
ILE A 111
None
0.90A 1qaoA-3tqsA:
23.5
1qaoA-3tqsA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 ILE A  39
GLY A  42
ALA A  45
ASN A 106
PRO A 108
None
0.97A 1sg9C-3tqsA:
11.5
1sg9C-3tqsA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
7 / 12 HIS A  13
GLY A  42
LEU A  66
ASP A  86
ILE A 111
MET A 132
SER A 182
None
0.85A 1zq9A-3tqsA:
27.6
1zq9A-3tqsA:
28.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
7 / 12 HIS A  13
GLY A  42
LEU A  66
PRO A 108
ILE A 111
MET A 132
SER A 182
None
0.60A 1zq9A-3tqsA:
27.6
1zq9A-3tqsA:
28.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
3 / 3 GLY A  40
GLU A  61
ASN A 106
None
0.25A 1zq9A-3tqsA:
27.4
1zq9A-3tqsA:
28.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
6 / 12 GLY A  40
GLY A  42
LEU A  66
ASP A  86
ASN A 106
PHE A 174
None
0.81A 1zq9B-3tqsA:
26.8
1zq9B-3tqsA:
28.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
9 / 12 HIS A  13
GLY A  40
GLY A  42
LEU A  66
ASN A 106
LEU A 107
PRO A 108
ILE A 111
PHE A 174
None
0.89A 1zq9B-3tqsA:
26.8
1zq9B-3tqsA:
28.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 11 GLU A  38
GLU A  61
ILE A  62
ASP A  63
ASP A  86
None
0.50A 2admA-3tqsA:
7.4
2admA-3tqsA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 GLY A 105
VAL A  25
GLY A  44
VAL A  20
ILE A  24
None
0.84A 2avoB-3tqsA:
undetectable
2avoB-3tqsA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 GLY A 105
VAL A  25
GLY A  44
VAL A  20
ILE A  24
None
0.85A 2bpxB-3tqsA:
undetectable
2bpxB-3tqsA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 11 LEU A  21
ILE A  24
LYS A  73
VAL A 104
GLY A 105
None
1.21A 2bxeA-3tqsA:
undetectable
2bxeA-3tqsA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 11 LEU A  21
ILE A  24
VAL A 104
GLY A 105
LEU A  50
None
1.18A 2bxeA-3tqsA:
undetectable
2bxeA-3tqsA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 ILE A  24
LYS A  73
VAL A 104
GLY A 105
LEU A  50
None
1.12A 2bxeB-3tqsA:
undetectable
2bxeB-3tqsA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 LEU A  21
ILE A  24
LYS A  73
VAL A 104
GLY A 105
None
1.22A 2bxeB-3tqsA:
undetectable
2bxeB-3tqsA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 GLY A 105
VAL A  25
GLY A  44
VAL A  20
ILE A  24
None
0.84A 2f8gB-3tqsA:
undetectable
2f8gB-3tqsA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 11 LEU A 115
LEU A 116
LEU A 153
ILE A  39
THR A 142
None
1.22A 2qd3A-3tqsA:
3.0
2qd3A-3tqsA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 ILE A 141
ILE A 126
LEU A 119
PHE A 131
HIS A 130
None
1.15A 2qo5A-3tqsA:
undetectable
2qo5A-3tqsA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
3 / 3 ARG A 214
ARG A 241
PRO A 242
None
0.93A 2wljA-3tqsA:
undetectable
2wljA-3tqsA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
4 / 7 THR A  47
GLN A  77
ILE A  80
ASP A  48
None
1.21A 2xytI-3tqsA:
undetectable
2xytI-3tqsA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 GLY A 105
VAL A  25
GLY A  44
VAL A  20
ILE A  24
None
0.69A 3bvbA-3tqsA:
undetectable
3bvbA-3tqsA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 11 GLU A  38
GLY A  40
GLU A  61
ASP A  86
ALA A  87
None
0.91A 3dxyA-3tqsA:
10.8
3dxyA-3tqsA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 11 GLU A  38
GLY A  40
GLY A  42
ASP A  86
ALA A  87
None
0.78A 3dxyA-3tqsA:
10.8
3dxyA-3tqsA:
23.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
6 / 12 GLY A  40
GLY A  42
GLU A  61
ASP A  63
ALA A  87
ILE A 111
None
0.81A 3fuuA-3tqsA:
26.4
3fuuA-3tqsA:
33.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
6 / 12 GLY A  40
GLY A  42
GLU A  61
ASP A  63
ASP A  86
ALA A  87
None
0.68A 3fuuA-3tqsA:
26.4
3fuuA-3tqsA:
33.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
3 / 3 SER A  93
GLN A 122
PHE A  92
None
0.76A 3g4lC-3tqsA:
undetectable
3g4lC-3tqsA:
21.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
10 / 11 GLY A  40
GLY A  42
GLU A  61
ILE A  62
ASP A  63
LEU A  66
ASP A  86
ALA A  87
ASN A 106
ILE A 111
None
0.98A 3grvA-3tqsA:
14.4
3grvA-3tqsA:
31.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
6 / 11 GLY A  40
GLY A  42
LEU A  70
ASP A  86
ALA A  87
ASN A 106
None
1.43A 3grvA-3tqsA:
14.4
3grvA-3tqsA:
31.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
7 / 11 GLY A  42
GLU A  61
ASP A  63
LEU A  66
ASN A 106
PRO A 108
ILE A 111
None
0.97A 3grvA-3tqsA:
14.4
3grvA-3tqsA:
31.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
10 / 12 LEU A  15
GLU A  38
GLY A  40
GLY A  42
GLU A  61
ILE A  62
ASP A  63
LEU A  66
ASP A  86
ALA A  87
None
0.80A 3gryA-3tqsA:
27.7
3gryA-3tqsA:
31.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
10 / 12 LEU A  15
GLU A  38
GLY A  42
GLU A  61
ILE A  62
ASP A  63
LEU A  66
ASP A  86
ALA A  87
ASN A 106
None
0.79A 3gryA-3tqsA:
27.7
3gryA-3tqsA:
31.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
6 / 12 LEU A  15
GLY A  40
GLY A  42
LEU A  70
ASP A  86
ALA A  87
None
1.44A 3gryA-3tqsA:
27.7
3gryA-3tqsA:
31.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
7 / 12 LEU A  15
GLY A  42
GLU A  61
ASP A  63
LEU A  66
ASN A 106
PRO A 108
None
0.98A 3gryA-3tqsA:
27.7
3gryA-3tqsA:
31.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
6 / 12 LEU A  15
GLY A  42
LEU A  70
ASP A  86
ALA A  87
ASN A 106
None
1.36A 3gryA-3tqsA:
27.7
3gryA-3tqsA:
31.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
8 / 12 LEU A  46
GLY A  42
GLU A  61
ILE A  62
ASP A  63
LEU A  66
ASP A  86
ALA A  87
None
1.35A 3gryA-3tqsA:
27.7
3gryA-3tqsA:
31.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 LEU A 115
LEU A 116
LEU A 153
ILE A  39
THR A 142
None
1.29A 4f4dA-3tqsA:
undetectable
4f4dA-3tqsA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
3 / 3 GLU A  61
ASP A  63
ASP A  86
None
0.34A 4gc9A-3tqsA:
26.7
4gc9A-3tqsA:
28.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 ALA A 143
ALA A 157
LEU A 153
SER A 154
LEU A 133
None
1.16A 4lnwA-3tqsA:
undetectable
4lnwA-3tqsA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 ALA A 143
ALA A 157
LEU A 153
SER A 154
LEU A 133
None
1.15A 4lnxA-3tqsA:
undetectable
4lnxA-3tqsA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 10 LEU A 115
LEU A 116
LEU A 153
ILE A  39
THR A 142
None
1.27A 4mk4A-3tqsA:
3.6
4mk4A-3tqsA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 LEU A  21
LYS A  73
VAL A 104
GLY A 105
LEU A  50
None
1.18A 4ot2A-3tqsA:
undetectable
4ot2A-3tqsA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
3 / 3 PRO A 242
VAL A 206
HIS A 205
None
0.65A 4pevC-3tqsA:
3.5
4pevC-3tqsA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
4 / 8 HIS A 205
SER A 212
ARG A 152
TRP A 231
None
1.01A 4uhxA-3tqsA:
1.6
4uhxA-3tqsA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 VAL A  25
GLU A  38
GLY A 105
TYR A  49
ILE A  39
None
1.36A 4xucA-3tqsA:
13.3
4xucA-3tqsA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 VAL A  25
GLU A  38
GLY A 105
TYR A  49
ILE A  39
None
1.36A 4xudA-3tqsA:
13.4
4xudA-3tqsA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
4 / 6 SER A 112
GLY A 105
ASN A 106
ILE A 185
None
1.09A 5j4nA-3tqsA:
undetectable
5j4nA-3tqsA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 11 GLY A  40
GLU A  61
ASP A  86
ALA A  87
LEU A 115
None
0.91A 5x6yA-3tqsA:
4.3
5x6yA-3tqsA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 10 GLY A  40
GLU A  61
ASP A  86
ALA A  87
LEU A 115
None
0.84A 5x6yB-3tqsA:
5.1
5x6yB-3tqsA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 11 GLY A  40
GLU A  61
ASP A  86
ALA A  87
LEU A 115
None
0.89A 5x6yC-3tqsA:
4.5
5x6yC-3tqsA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
5 / 12 GLY A 105
VAL A  25
GLY A  44
VAL A  20
ILE A  24
None
0.63A 6dj1A-3tqsA:
undetectable
6dj1A-3tqsA:
19.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Coxiella
burnetii)
9 / 12 PHE A  14
LEU A  15
GLU A  38
ILE A  39
GLY A  40
GLY A  42
ALA A  45
ASP A  63
LEU A  66
None
0.73A 6iftA-3tqsA:
27.9
6iftA-3tqsA:
32.53