SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tqw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 3tqw METHIONINE-BINDING
PROTEIN
(Coxiella
burnetii) 		3 / 3 GLU A  11
ALA A   8
SER A  36
 MET  A 238 (-3.2A)
None
None
 0.70A 1errB-3tqwA:
undetectable		 1errB-3tqwA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 3tqw METHIONINE-BINDING
PROTEIN
(Coxiella
burnetii) 		4 / 8 ASP A  37
TYR A 172
TYR A  60
HIS A  57
 None
None
MET  A 238 (-3.7A)
MET  A 238 (-3.5A)
 1.48A 2ha2A-3tqwA:
undetectable		 2ha2A-3tqwA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 3tqw METHIONINE-BINDING
PROTEIN
(Coxiella
burnetii) 		4 / 8 ASP A  37
TYR A 172
TYR A  60
HIS A  57
 None
None
MET  A 238 (-3.7A)
MET  A 238 (-3.5A)
 1.47A 2ha2B-3tqwA:
undetectable		 2ha2B-3tqwA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 3tqw METHIONINE-BINDING
PROTEIN
(Coxiella
burnetii) 		5 / 9 ASP A  47
GLY A  48
ILE A  72
GLY A   5
ILE A  33
 None
 0.80A 3ogpA-3tqwA:
undetectable		 3ogpA-3tqwA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 3tqw METHIONINE-BINDING
PROTEIN
(Coxiella
burnetii) 		5 / 9 ASP A  47
GLY A  48
ILE A  72
GLY A   5
ILE A  33
 None
 0.86A 3ogpB-3tqwA:
undetectable		 3ogpB-3tqwA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3tqw METHIONINE-BINDING
PROTEIN
(Coxiella
burnetii) 		4 / 5 ASP A  51
VAL A  50
GLY A  48
ASP A 204
 None
 1.49A 3w9tA-3tqwA:
undetectable		 3w9tA-3tqwA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3tqw METHIONINE-BINDING
PROTEIN
(Coxiella
burnetii) 		4 / 5 ASP A  51
VAL A  50
GLY A  48
ASP A 204
 None
 1.48A 3w9tC-3tqwA:
undetectable		 3w9tC-3tqwA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 3tqw METHIONINE-BINDING
PROTEIN
(Coxiella
burnetii) 		4 / 5 ASP A  51
VAL A  50
GLY A  48
ASP A 204
 None
 1.49A 3w9tE-3tqwA:
undetectable		 3w9tE-3tqwA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 3tqw METHIONINE-BINDING
PROTEIN
(Coxiella
burnetii) 		4 / 5 ASP A  51
VAL A  50
GLY A  48
ASP A 204
 None
 1.49A 3w9tG-3tqwA:
undetectable		 3w9tG-3tqwA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 3tqw METHIONINE-BINDING
PROTEIN
(Coxiella
burnetii) 		3 / 3 ASP A  51
ARG A   3
ASP A  47
 None
 0.81A 4fp9D-3tqwA:
undetectable		 4fp9D-3tqwA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3tqw METHIONINE-BINDING
PROTEIN
(Coxiella
burnetii) 		3 / 3 ASP A  51
ARG A   3
ASP A  47
 None
 0.83A 5zvgA-3tqwA:
undetectable		 5zvgA-3tqwA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3tqw METHIONINE-BINDING
PROTEIN
(Coxiella
burnetii) 		3 / 3 ASP A  51
ARG A   3
ASP A  47
 None
 0.81A 5zvgB-3tqwA:
undetectable		 5zvgB-3tqwA:
23.38