SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3tqz DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Coxiella
burnetii) 		4 / 8 ILE A 125
LEU A 123
VAL A  86
GLY A  87
 None
 0.86A 3w1wA-3tqzA:
undetectable		 3w1wA-3tqzA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 3tqz DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Coxiella
burnetii) 		3 / 3 ARG A  13
PHE A  18
PRO A  19
 None
 0.62A 3zoaB-3tqzA:
undetectable		 3zoaB-3tqzA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3tqz DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Coxiella
burnetii) 		5 / 10 LEU A  33
ASP A  32
LEU A  20
LEU A   7
ILE A  57
 None
 0.97A 4odoA-3tqzA:
undetectable		 4odoA-3tqzA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3tqz DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Coxiella
burnetii) 		5 / 10 LEU A  33
ASP A  32
LEU A  20
LEU A   7
ILE A  57
 None
 1.07A 4odoC-3tqzA:
undetectable		 4odoC-3tqzA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 3tqz DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Coxiella
burnetii) 		5 / 11 LEU A  33
ASP A  32
LEU A  20
LEU A   7
ILE A  57
 None
 0.92A 4odrA-3tqzA:
undetectable
4odrB-3tqzA:
undetectable		 4odrA-3tqzA:
23.87
4odrB-3tqzA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 3tqz DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Coxiella
burnetii) 		3 / 3 MET A  98
GLN A  94
TYR A  58
 None
 1.01A 4udcA-3tqzA:
undetectable		 4udcA-3tqzA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3tqz DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Coxiella
burnetii) 		4 / 7 LEU A  33
THR A  53
PRO A  21
LEU A  10
 None
 0.90A 5fxtA-3tqzA:
undetectable		 5fxtA-3tqzA:
19.89