SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tr7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 7 TYR A  69
VAL A  82
ILE A  95
GLY A 111
 None
 0.89A 11gsA-3tr7A:
undetectable		 11gsA-3tr7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		3 / 3 GLN A 175
ILE A  59
HIS A 157
 None
 0.57A 1fm9A-3tr7A:
undetectable		 1fm9A-3tr7A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		3 / 3 GLN A 175
ILE A  59
HIS A 157
 None
 0.58A 1k74A-3tr7A:
undetectable		 1k74A-3tr7A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		3 / 3 GLN A   8
HIS A 157
ARG A 181
 None
 1.01A 1zlqA-3tr7A:
undetectable		 1zlqA-3tr7A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		5 / 10 TYR A  69
PHE A 205
LEU A 113
LEU A 123
ILE A  63
 None
 1.10A 2bxeB-3tr7A:
undetectable		 2bxeB-3tr7A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		5 / 12 LEU A 176
ILE A 177
LEU A 124
VAL A  62
LEU A  64
 None
 1.10A 2bxfB-3tr7A:
undetectable		 2bxfB-3tr7A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 8 TYR A  69
VAL A  82
ILE A  95
GLY A 111
 None
 0.88A 2gssA-3tr7A:
undetectable		 2gssA-3tr7A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 8 TYR A  69
VAL A  82
ILE A  95
GLY A 111
 None
 0.88A 2gssB-3tr7A:
undetectable		 2gssB-3tr7A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		5 / 9 ALA A  75
TYR A  41
ALA A 132
GLY A 133
ILE A  40
 None
 1.13A 2v7bA-3tr7A:
undetectable		 2v7bA-3tr7A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_B_BEZB1529_0
(BENZOATE-COENZYME A
LIGASE)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		5 / 9 ALA A  75
TYR A  41
ALA A 132
GLY A 133
ILE A  40
 None
 1.13A 2v7bB-3tr7A:
undetectable		 2v7bB-3tr7A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_A_PFNA1372_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		5 / 11 LEU A  78
LEU A 123
LYS A 115
HIS A 110
PRO A 108
 None
 1.47A 2x7hA-3tr7A:
undetectable
2x7hB-3tr7A:
1.7		 2x7hA-3tr7A:
22.01
2x7hB-3tr7A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 7 TYR A  69
VAL A  82
ILE A  95
GLY A 111
 None
 0.87A 3gssA-3tr7A:
undetectable		 3gssA-3tr7A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 7 TYR A  69
VAL A  82
ILE A  95
GLY A 111
 None
 0.87A 3gssB-3tr7A:
undetectable		 3gssB-3tr7A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		3 / 3 ILE A  63
PHE A 205
HIS A 189
 None
 0.65A 3h0aA-3tr7A:
undetectable		 3h0aA-3tr7A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 8 TYR A  69
VAL A  82
ILE A  95
GLY A 111
 None
 0.91A 3hjoA-3tr7A:
undetectable		 3hjoA-3tr7A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		3 / 3 LYS A 173
ILE A  26
PHE A  29
 None
 0.95A 3j7zS-3tr7A:
undetectable
3j7za-3tr7A:
undetectable		 3j7zS-3tr7A:
17.78
3j7za-3tr7A:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		5 / 9 ALA A 208
VAL A 121
ILE A  95
LEU A 113
ILE A  63
 None
 1.21A 3jw3B-3tr7A:
undetectable		 3jw3B-3tr7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 5 ILE A 141
PHE A  29
ASP A  28
GLU A  25
 None
 1.05A 3kp6A-3tr7A:
undetectable
3kp6B-3tr7A:
undetectable		 3kp6A-3tr7A:
24.58
3kp6B-3tr7A:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 8 TYR A  69
VAL A  82
ILE A  95
GLY A 111
 None
 0.92A 3n9jA-3tr7A:
undetectable		 3n9jA-3tr7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 5 GLU A 114
LEU A 113
HIS A 110
GLY A 111
 None
 1.18A 3pp1A-3tr7A:
undetectable		 3pp1A-3tr7A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		5 / 12 ILE A  47
GLN A  44
ILE A 141
ALA A 127
ILE A  40
 None
 1.10A 4rp8C-3tr7A:
undetectable		 4rp8C-3tr7A:
18.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		5 / 8 GLY A  65
TYR A  69
PHE A  80
SER A  91
ASN A 125
 None
 0.74A 4wryA-3tr7A:
31.1		 4wryA-3tr7A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		5 / 8 GLY A  65
TYR A  69
PHE A  80
SER A  91
ASN A 125
 None
 0.79A 4wrzA-3tr7A:
30.6		 4wrzA-3tr7A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 8 TYR A  69
PHE A  80
SER A  91
HIS A 189
 None
 0.75A 4wrzA-3tr7A:
30.6		 4wrzA-3tr7A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 7 GLN A  66
TYR A  69
PHE A  80
ASN A 125
 None
 1.04A 4ws0A-3tr7A:
30.5		 4ws0A-3tr7A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 7 GLY A  65
TYR A  69
PHE A  80
ASN A 125
 None
 0.65A 4ws0A-3tr7A:
30.5		 4ws0A-3tr7A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		5 / 8 GLN A  66
TYR A  69
PHE A  80
SER A  91
ASN A 125
 None
 1.13A 4ws1A-3tr7A:
30.6		 4ws1A-3tr7A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		5 / 8 GLY A  65
TYR A  69
PHE A  80
SER A  91
ASN A 125
 None
 0.83A 4ws1A-3tr7A:
30.6		 4ws1A-3tr7A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 8 TYR A  69
PHE A  80
SER A  91
HIS A 189
 None
 0.78A 4ws1A-3tr7A:
30.6		 4ws1A-3tr7A:
41.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA609_0
(ACETYLCHOLINESTERASE)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 6 ASP A  67
TRP A 143
HIS A 138
TYR A  22
 None
 1.36A 5ov9A-3tr7A:
undetectable		 5ov9A-3tr7A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		4 / 7 ASP A  67
TRP A 143
HIS A 138
TYR A  22
 None
 1.42A 5ov9B-3tr7A:
0.9		 5ov9B-3tr7A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		3 / 3 GLN A 175
ILE A  59
HIS A 157
 None
 0.56A 5z12B-3tr7A:
undetectable		 5z12B-3tr7A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3tr7 URACIL-DNA
GLYCOSYLASE
(Coxiella
burnetii) 		3 / 3 ASN A 125
VAL A  30
HIS A 138
 None
 0.87A 6a5yD-3tr7A:
undetectable		 6a5yD-3tr7A:
16.38