SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tr8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 3tr8 OLIGORIBONUCLEASE
(Coxiella
burnetii) 		5 / 12 ALA A  45
LEU A  71
ILE A  26
ILE A  48
LEU A 159
 None
 1.11A 1xdkB-3tr8A:
undetectable		 1xdkB-3tr8A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3tr8 OLIGORIBONUCLEASE
(Coxiella
burnetii) 		4 / 5 ARG A 113
GLN A 111
LEU A 104
PHE A 127
 None
 1.12A 3ablC-3tr8A:
undetectable
3ablJ-3tr8A:
undetectable		 3ablC-3tr8A:
20.07
3ablJ-3tr8A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3tr8 OLIGORIBONUCLEASE
(Coxiella
burnetii) 		4 / 6 ARG A 113
GLN A 111
LEU A 104
PHE A 127
 None
 1.11A 3ablP-3tr8A:
undetectable
3ablW-3tr8A:
undetectable		 3ablP-3tr8A:
20.07
3ablW-3tr8A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 3tr8 OLIGORIBONUCLEASE
(Coxiella
burnetii) 		4 / 6 ASP A 133
ASP A 112
LEU A 116
TRP A  10
 None
MN  A 185 ( 4.3A)
None
None
 1.16A 3bj8C-3tr8A:
undetectable
3bj8D-3tr8A:
undetectable		 3bj8C-3tr8A:
22.22
3bj8D-3tr8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 3tr8 OLIGORIBONUCLEASE
(Coxiella
burnetii) 		5 / 9 ASP A  59
THR A  16
ASN A  62
GLY A  17
ASP A  19
 None
 1.34A 3sfuA-3tr8A:
undetectable		 3sfuA-3tr8A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 3tr8 OLIGORIBONUCLEASE
(Coxiella
burnetii) 		5 / 9 ASP A  59
THR A  16
ASN A  62
GLY A  17
ASP A  19
 None
 1.33A 3sfuB-3tr8A:
undetectable		 3sfuB-3tr8A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3tr8 OLIGORIBONUCLEASE
(Coxiella
burnetii) 		4 / 6 ARG A 113
GLN A 111
LEU A 104
PHE A 127
 None
 1.17A 5b1bC-3tr8A:
undetectable
5b1bJ-3tr8A:
undetectable		 5b1bC-3tr8A:
20.07
5b1bJ-3tr8A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3tr8 OLIGORIBONUCLEASE
(Coxiella
burnetii) 		4 / 4 LEU A  40
ARG A 172
ILE A  39
ILE A 168
 None
 1.36A 5dzk2-3tr8A:
undetectable
5dzkM-3tr8A:
undetectable
5dzkN-3tr8A:
undetectable		 5dzk2-3tr8A:
2.67
5dzkM-3tr8A:
24.66
5dzkN-3tr8A:
24.66