SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3trf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KVL_A_CLSA371_1 (BETA-LACTAMASE)	3trf	SHIKIMATE KINASE (Coxiella burnetii)	5 / 10	GLY A 83 LEU A 145 TYR A 146 THR A 81 GLY A 82	None	1.17A	1kvlA-3trfA: undetectable	1kvlA-3trfA: 20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_A_SAMA293_0 (GLYCINE N-METHYLTRANSFERASE)	3trf	SHIKIMATE KINASE (Coxiella burnetii)	5 / 12	ILE A 11 VAL A 86 ALA A 70 GLY A 82 SER A 36	None	1.12A	1nbiA-3trfA: undetectable	1nbiA-3trfA: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_B_SAMB1293_0 (GLYCINE N-METHYLTRANSFERASE)	3trf	SHIKIMATE KINASE (Coxiella burnetii)	5 / 12	ILE A 11 VAL A 86 ALA A 70 GLY A 82 SER A 36	None	1.11A	1nbiB-3trfA: undetectable	1nbiB-3trfA: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JZJ_A_ACRA405_1 (ACARBOSE/MALTOSE BINDING PROTEIN GACH)	3trf	SHIKIMATE KINASE (Coxiella burnetii)	5 / 12	GLU A 41 PHE A 52 GLY A 56 GLY A 83 ARG A 142	None	1.32A	3jzjA-3trfA: undetectable	3jzjA-3trfA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FNA_B_BEZB302_0 (14-3-3 PROTEIN ZETA/DELTA)	3trf	SHIKIMATE KINASE (Coxiella burnetii)	3 / 3	MET A 14 GLN A 111 ARG A 114	None	1.12A	6fnaB-3trfA: undetectable	6fnaB-3trfA: 24.69

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KVL_A_CLSA371_1","BETA-LACTAMASE","3trf","SHIKIMATE KINASE","Coxiella burnetii",5,"GLY A  83;LEU A 145;TYR A 146;THR A  81;GLY A  82","None","1.17A","1kvlA-3trfA:undetectable","1kvlA-3trfA:20.94"],["1NBI_A_SAMA293_0","GLYCINE N-METHYLTRANSFERASE","3trf","SHIKIMATE KINASE","Coxiella burnetii",5,"ILE A  11;VAL A  86;ALA A  70;GLY A  82;SER A  36","None","1.12A","1nbiA-3trfA:undetectable","1nbiA-3trfA:21.31"],["1NBI_B_SAMB1293_0","GLYCINE N-METHYLTRANSFERASE","3trf","SHIKIMATE KINASE","Coxiella burnetii",5,"ILE A  11;VAL A  86;ALA A  70;GLY A  82;SER A  36","None","1.11A","1nbiB-3trfA:undetectable","1nbiB-3trfA:21.31"],["3JZJ_A_ACRA405_1","ACARBOSE\/MALTOSE BINDING PROTEIN GACH","3trf","SHIKIMATE KINASE","Coxiella burnetii",5,"GLU A  41;PHE A  52;GLY A  56;GLY A  83;ARG A 142","None","1.32A","3jzjA-3trfA:undetectable","3jzjA-3trfA:17.19"],["6FNA_B_BEZB302_0","14-3-3 PROTEIN ZETA\/DELTA","3trf","SHIKIMATE KINASE","Coxiella burnetii",3,"MET A  14;GLN A 111;ARG A 114","None","1.12A","6fnaB-3trfA:undetectable","6fnaB-3trfA:24.69"]]