SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3trh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3trh PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CARBOXYLTRANSFERASE
SUBUNIT
(Coxiella
burnetii) 		5 / 12 GLY A 118
ALA A  22
GLY A  86
THR A 115
ILE A  85
 None
 0.92A 1gtnL-3trhA:
undetectable
1gtnV-3trhA:
undetectable		 1gtnL-3trhA:
18.79
1gtnV-3trhA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3trh PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CARBOXYLTRANSFERASE
SUBUNIT
(Coxiella
burnetii) 		5 / 12 GLY A  86
THR A 115
ILE A  85
GLY A 118
ALA A  22
 None
 0.97A 1utdL-3trhA:
undetectable
1utdM-3trhA:
undetectable		 1utdL-3trhA:
18.79
1utdM-3trhA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3trh PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CARBOXYLTRANSFERASE
SUBUNIT
(Coxiella
burnetii) 		5 / 12 GLY A  86
THR A 115
ILE A  85
GLY A 118
ALA A  22
 None
 0.95A 1utdO-3trhA:
undetectable
1utdP-3trhA:
undetectable		 1utdO-3trhA:
18.79
1utdP-3trhA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3trh PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CARBOXYLTRANSFERASE
SUBUNIT
(Coxiella
burnetii) 		5 / 11 GLY A  86
THR A 115
ILE A  85
GLY A 118
ALA A  22
 None
 0.94A 1utdP-3trhA:
undetectable
1utdQ-3trhA:
undetectable		 1utdP-3trhA:
18.79
1utdQ-3trhA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)		 3trh PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CARBOXYLTRANSFERASE
SUBUNIT
(Coxiella
burnetii) 		5 / 12 GLY A  67
ALA A  66
ASP A  15
GLY A 118
ILE A 117
 None
 1.06A 2b7zA-3trhA:
undetectable		 2b7zA-3trhA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_2
(HIV-1 PROTEASE)		 3trh PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CARBOXYLTRANSFERASE
SUBUNIT
(Coxiella
burnetii) 		5 / 12 GLY A  67
ALA A  66
ASP A  15
GLY A 118
ILE A 117
 None
 1.04A 2b7zB-3trhA:
undetectable		 2b7zB-3trhA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 3trh PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CARBOXYLTRANSFERASE
SUBUNIT
(Coxiella
burnetii) 		5 / 12 GLY A  67
ALA A  66
ASP A  15
GLY A 118
ILE A 117
 None
 1.04A 3d1zB-3trhA:
undetectable		 3d1zB-3trhA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 3trh PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CARBOXYLTRANSFERASE
SUBUNIT
(Coxiella
burnetii) 		5 / 10 GLY A  67
ALA A  66
ASP A  15
GLY A 118
ILE A 117
 None
 1.07A 3el9B-3trhA:
undetectable		 3el9B-3trhA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3trh PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CARBOXYLTRANSFERASE
SUBUNIT
(Coxiella
burnetii) 		5 / 11 ILE A  63
ALA A  64
ALA A  65
ALA A  73
ILE A 127
 None
 0.96A 3fc6A-3trhA:
undetectable		 3fc6A-3trhA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 3trh PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CARBOXYLTRANSFERASE
SUBUNIT
(Coxiella
burnetii) 		5 / 9 GLY A  67
ALA A  66
ASP A  15
GLY A 118
ILE A 117
 None
 0.92A 3ogpA-3trhA:
undetectable		 3ogpA-3trhA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 3trh PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CARBOXYLTRANSFERASE
SUBUNIT
(Coxiella
burnetii) 		5 / 12 GLY A  67
ALA A  66
ASP A  15
GLY A 118
ILE A 117
 None
 0.98A 3ogqB-3trhA:
undetectable		 3ogqB-3trhA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 3trh PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CARBOXYLTRANSFERASE
SUBUNIT
(Coxiella
burnetii) 		5 / 12 GLY A  67
ALA A  66
ASP A  15
GLY A 118
ILE A 117
 None
 1.02A 3ucbA-3trhA:
undetectable		 3ucbA-3trhA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3trh PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CARBOXYLTRANSFERASE
SUBUNIT
(Coxiella
burnetii) 		5 / 12 ALA A  66
GLY A  11
LEU A  68
ALA A  99
ALA A  64
 None
 1.40A 5jglB-3trhA:
undetectable		 5jglB-3trhA:
20.68