SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tri'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TW4_A_CHDA130_0 (FATTY ACID-BINDING PROTEIN)	3tri	PYRROLINE-5-CARBOXYL ATE REDUCTASE (Coxiella burnetii)	5 / 12	LEU A 93 LEU A 87 ALA A 61 THR A 35 ILE A 151	None	1.11A	1tw4A-3triA: undetectable	1tw4A-3triA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB2_A_SAMA1101_0 (STRUCTURAL PROTEIN VP3)	3tri	PYRROLINE-5-CARBOXYL ATE REDUCTASE (Coxiella burnetii)	5 / 12	PRO A 178 GLY A 133 VAL A 161 ILE A 167 GLU A 164	None	1.41A	3jb2A-3triA: undetectable	3jb2A-3triA: 15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KR2_A_ROCA101_1 (PROTEASE PR5-SQV)	3tri	PYRROLINE-5-CARBOXYL ATE REDUCTASE (Coxiella burnetii)	5 / 9	ASN A 63 ALA A 64 ILE A 9 ILE A 32 THR A 54	PO4 A 283 (-3.1A) PO4 A 283 (-3.5A) None None None	1.13A	5kr2A-3triA: undetectable	5kr2A-3triA: 17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KR2_C_ROCC101_1 (PROTEASE PR5-SQV)	3tri	PYRROLINE-5-CARBOXYL ATE REDUCTASE (Coxiella burnetii)	5 / 9	ASN A 63 ALA A 64 ILE A 9 ILE A 32 THR A 54	PO4 A 283 (-3.1A) PO4 A 283 (-3.5A) None None None	1.02A	5kr2C-3triA: undetectable	5kr2C-3triA: 17.20

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TW4_A_CHDA130_0","FATTY ACID-BINDING PROTEIN","3tri","PYRROLINE-5-CARBOXYLATE REDUCTASE","Coxiella burnetii",5,"LEU A  93;LEU A  87;ALA A  61;THR A  35;ILE A 151","None","1.11A","1tw4A-3triA:undetectable","1tw4A-3triA:18.75"],["3JB2_A_SAMA1101_0","STRUCTURAL PROTEIN VP3","3tri","PYRROLINE-5-CARBOXYLATE REDUCTASE","Coxiella burnetii",5,"PRO A 178;GLY A 133;VAL A 161;ILE A 167;GLU A 164","None","1.41A","3jb2A-3triA:undetectable","3jb2A-3triA:15.07"],["5KR2_A_ROCA101_1","PROTEASE PR5-SQV","3tri","PYRROLINE-5-CARBOXYLATE REDUCTASE","Coxiella burnetii",5,"ASN A  63;ALA A  64;ILE A   9;ILE A  32;THR A  54","PO4 A 283 (-3.1A);PO4 A 283 (-3.5A);None;None;None","1.13A","5kr2A-3triA:undetectable","5kr2A-3triA:17.20"],["5KR2_C_ROCC101_1","PROTEASE PR5-SQV","3tri","PYRROLINE-5-CARBOXYLATE REDUCTASE","Coxiella burnetii",5,"ASN A  63;ALA A  64;ILE A   9;ILE A  32;THR A  54","PO4 A 283 (-3.1A);PO4 A 283 (-3.5A);None;None;None","1.02A","5kr2C-3triA:undetectable","5kr2C-3triA:17.20"]]