SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3trj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 3trj PHOSPHOHEPTOSE
ISOMERASE
(Francisella
tularensis) 		5 / 12 ILE A 180
VAL A 165
ILE A 173
SER A  54
LEU A 116
 None
 1.24A 1fm4A-3trjA:
undetectable		 1fm4A-3trjA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3trj PHOSPHOHEPTOSE
ISOMERASE
(Francisella
tularensis) 		3 / 3 MET A 155
ASN A 126
GLN A  99
 None
 0.98A 1xoqB-3trjA:
undetectable		 1xoqB-3trjA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3trj PHOSPHOHEPTOSE
ISOMERASE
(Francisella
tularensis) 		5 / 12 LEU A 115
CYH A  49
HIS A 177
LEU A 152
GLY A 122
 None
 1.36A 3okxA-3trjA:
undetectable		 3okxA-3trjA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3trj PHOSPHOHEPTOSE
ISOMERASE
(Francisella
tularensis) 		5 / 12 ILE A 180
VAL A 165
ILE A 173
SER A  54
LEU A 116
 None
 1.21A 4a84A-3trjA:
undetectable		 4a84A-3trjA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 3trj PHOSPHOHEPTOSE
ISOMERASE
(Francisella
tularensis) 		3 / 3 ARG A 164
TYR A 156
GLU A 162
 None
 0.65A 4zzbE-3trjA:
undetectable		 4zzbE-3trjA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 3trj PHOSPHOHEPTOSE
ISOMERASE
(Francisella
tularensis) 		3 / 3 THR A  62
ALA A  78
LYS A  45
 None
 0.77A 6fgcA-3trjA:
3.7		 6fgcA-3trjA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 3trj PHOSPHOHEPTOSE
ISOMERASE
(Francisella
tularensis) 		3 / 3 THR A  62
ALA A  78
LYS A  45
 None
 0.76A 6fgdA-3trjA:
3.8		 6fgdA-3trjA:
19.85