SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ts7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 11 SER A  84
LEU A  85
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 0.89A 1rqjA-3ts7A:
36.7		 1rqjA-3ts7A:
47.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 11 SER A  84
LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.74A 1rqjA-3ts7A:
36.7		 1rqjA-3ts7A:
47.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 11 SER A  84
LEU A  85
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 0.89A 1rqjB-3ts7A:
36.5		 1rqjB-3ts7A:
47.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 11 SER A  84
LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.72A 1rqjB-3ts7A:
36.5		 1rqjB-3ts7A:
47.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 11 LEU A  85
ASP A  88
ASP A  94
LYS A 185
THR A 186
 None
 1.13A 1yhlA-3ts7A:
24.9		 1yhlA-3ts7A:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 11 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.78A 1yhlA-3ts7A:
24.9		 1yhlA-3ts7A:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 11 LEU A  85
ASP A  88
ASP A  94
GLN A 162
LYS A 185
THR A 186
 None
 1.35A 1yq7A-3ts7A:
23.9		 1yq7A-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 11 LEU A  85
ASP A  94
ARG A  99
GLN A 162
LYS A 185
THR A 186
 None
 1.06A 1yq7A-3ts7A:
23.9		 1yq7A-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 10 LEU A  85
ASP A  88
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 1.18A 1yv5A-3ts7A:
24.0		 1yv5A-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 10 LEU A  85
ASP A  88
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.96A 1yv5A-3ts7A:
24.0		 1yv5A-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 9 ASP A  88
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 1.34A 1zw5A-3ts7A:
24.4		 1zw5A-3ts7A:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 9 ASP A  88
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 1.18A 1zw5A-3ts7A:
24.4		 1zw5A-3ts7A:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 12 GLY A 220
GLY A 187
GLN A 224
THR A 186
ILE A 296
 None
 1.27A 2azxA-3ts7A:
undetectable		 2azxA-3ts7A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 12 GLY A 220
GLY A 187
GLN A 224
THR A 186
ILE A 296
 None
 1.30A 2azxB-3ts7A:
undetectable		 2azxB-3ts7A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		4 / 8 ALA A  74
ALA A  21
LEU A 129
VAL A 128
 None
 0.91A 2bxgA-3ts7A:
2.0		 2bxgA-3ts7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR2_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 11 GLY A 220
GLY A 187
GLN A 224
THR A 186
ILE A 296
 None
 1.27A 2dr2A-3ts7A:
undetectable		 2dr2A-3ts7A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 9 ASP A  88
ASP A  94
GLN A 162
LYS A 185
THR A 186
 None
 1.27A 2e91B-3ts7A:
18.8		 2e91B-3ts7A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 9 ASP A  94
ARG A  99
GLN A 162
LYS A 185
THR A 186
 None
 1.04A 2e91B-3ts7A:
18.8		 2e91B-3ts7A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 11 LEU A  85
ASP A  88
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 1.20A 2f8cF-3ts7A:
24.8		 2f8cF-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 11 LEU A  85
ASP A  88
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 1.03A 2f8cF-3ts7A:
24.8		 2f8cF-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 10 LEU A  85
ASP A  88
ARG A  99
GLN A 162
LYS A 185
THR A 186
 None
 1.38A 2f8zF-3ts7A:
25.1		 2f8zF-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 10 LEU A  85
ASP A  94
ARG A  99
GLN A 162
LYS A 185
THR A 186
 None
 1.10A 2f8zF-3ts7A:
25.1		 2f8zF-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 12 LEU A  85
ASP A  88
ARG A  99
LYS A 185
THR A 186
 None
 0.98A 2f94F-3ts7A:
24.6		 2f94F-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 12 LEU A  85
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 0.60A 2f94F-3ts7A:
24.6		 2f94F-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 12 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.68A 2f94F-3ts7A:
24.6		 2f94F-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 0.93A 2f9kF-3ts7A:
24.6		 2f9kF-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.82A 2f9kF-3ts7A:
24.6		 2f9kF-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 9 LEU A  85
ASP A  88
ASP A  94
LYS A 185
THR A 186
 None
 1.12A 2o1oA-3ts7A:
23.9		 2o1oA-3ts7A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 9 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.68A 2o1oA-3ts7A:
23.9		 2o1oA-3ts7A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ASP A  94
ARG A  99
GLN A 162
 None
 1.33A 2o1oB-3ts7A:
24.6		 2o1oB-3ts7A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 10 LEU A  85
ASP A  88
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 1.19A 2o1oB-3ts7A:
24.6		 2o1oB-3ts7A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ASP A  94
LYS A 185
THR A 186
 None
 1.27A 2q58A-3ts7A:
24.0		 2q58A-3ts7A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.97A 2q58A-3ts7A:
24.0		 2q58A-3ts7A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ASP A  94
ARG A  99
GLN A 162
 None
 1.28A 2qisA-3ts7A:
24.6		 2qisA-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ASP A  94
ARG A  99
LYS A 185
 None
 1.06A 2qisA-3ts7A:
24.6		 2qisA-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ASP A  94
LYS A 185
THR A 186
 None
 1.13A 3ez3D-3ts7A:
23.6		 3ez3D-3ts7A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.78A 3ez3D-3ts7A:
23.6		 3ez3D-3ts7A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 ASP A  88
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 1.12A 3ibaA-3ts7A:
24.7		 3ibaA-3ts7A:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		3 / 3 GLU A  19
LEU A  22
ASP A  23
 None
 0.36A 3ko0A-3ts7A:
undetectable		 3ko0A-3ts7A:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		3 / 3 GLU A  19
LEU A  22
ASP A  23
 None
 0.26A 3ko0T-3ts7A:
undetectable		 3ko0T-3ts7A:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 12 ARG A 100
GLY A 220
MET A  51
LEU A  55
ILE A 190
 PO4  A 324 (-3.8A)
None
PO4  A 323 (-3.8A)
None
None
 0.94A 3ku1A-3ts7A:
undetectable		 3ku1A-3ts7A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 12 ARG A 100
GLY A 220
MET A  51
LEU A  55
ILE A 190
 PO4  A 324 (-3.8A)
None
PO4  A 323 (-3.8A)
None
None
 0.88A 3ku1C-3ts7A:
undetectable		 3ku1C-3ts7A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 12 ARG A 100
GLY A 220
MET A  51
LEU A  55
ILE A 190
 PO4  A 324 (-3.8A)
None
PO4  A 323 (-3.8A)
None
None
 0.92A 3ku1H-3ts7A:
undetectable		 3ku1H-3ts7A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 11 LEU A  85
ASP A  88
ARG A  99
GLN A 162
THR A 186
 None
 1.35A 3n45F-3ts7A:
24.6		 3n45F-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 11 LEU A  85
ASP A  88
ARG A  99
LYS A 185
THR A 186
 None
 1.05A 3n45F-3ts7A:
24.6		 3n45F-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 11 LEU A  85
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 0.93A 3n45F-3ts7A:
24.6		 3n45F-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 11 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.81A 3n45F-3ts7A:
24.6		 3n45F-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ASP A  94
GLN A 162
THR A 186
 None
 1.28A 3n46F-3ts7A:
24.6		 3n46F-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ASP A  94
LYS A 185
THR A 186
 None
 1.07A 3n46F-3ts7A:
24.6		 3n46F-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 0.94A 3n46F-3ts7A:
24.6		 3n46F-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.82A 3n46F-3ts7A:
24.6		 3n46F-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		4 / 6 LEU A  69
VAL A  65
VAL A 137
PHE A 209
 None
 1.13A 3soaA-3ts7A:
undetectable		 3soaA-3ts7A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 12 TYR A  57
VAL A  18
SER A 134
VAL A 128
LEU A 129
 None
 1.18A 3w68A-3ts7A:
2.4		 3w68A-3ts7A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 7 LEU A  55
THR A  62
ALA A  58
LEU A  54
SER A  14
 None
 1.26A 4d7bA-3ts7A:
undetectable		 4d7bA-3ts7A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		4 / 8 LEU A  55
THR A  62
ALA A  58
LEU A  54
 None
 0.96A 4ik6B-3ts7A:
undetectable		 4ik6B-3ts7A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 9 LEU A  85
ASP A  88
ASP A  94
GLN A 162
LYS A 185
 None
 1.40A 4kfaA-3ts7A:
24.3		 4kfaA-3ts7A:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 9 LEU A  85
ASP A  94
ARG A  99
GLN A 162
LYS A 185
 None
 1.08A 4kfaA-3ts7A:
24.3		 4kfaA-3ts7A:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 0.89A 4kpdA-3ts7A:
25.0		 4kpdA-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.76A 4kpdA-3ts7A:
25.0		 4kpdA-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 9 LEU A  85
ASP A  88
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 1.03A 4kpjA-3ts7A:
24.3		 4kpjA-3ts7A:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 0.92A 4kq5A-3ts7A:
24.3		 4kq5A-3ts7A:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.81A 4kq5A-3ts7A:
24.3		 4kq5A-3ts7A:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 10 LEU A  85
ASP A  88
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 1.21A 4kqsA-3ts7A:
24.8		 4kqsA-3ts7A:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 10 LEU A  85
ASP A  88
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 1.03A 4kqsA-3ts7A:
24.8		 4kqsA-3ts7A:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 12 LEU A  85
ASP A  88
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 1.03A 4ng6A-3ts7A:
24.5		 4ng6A-3ts7A:
25.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 10 LEU A  85
ASP A  88
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 1.19A 4nkeA-3ts7A:
24.4		 4nkeA-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 10 LEU A  85
ASP A  88
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 1.00A 4nkeA-3ts7A:
24.4		 4nkeA-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 9 LEU A  85
ASP A  88
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 1.04A 4nkfA-3ts7A:
24.6		 4nkfA-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ARG A  99
GLN A 162
THR A 186
 None
 1.29A 4nuaA-3ts7A:
24.6		 4nuaA-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ARG A  99
LYS A 185
THR A 186
 None
 0.98A 4nuaA-3ts7A:
24.6		 4nuaA-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 0.84A 4nuaA-3ts7A:
24.6		 4nuaA-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.71A 4nuaA-3ts7A:
24.6		 4nuaA-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 9 LEU A  85
ASP A  88
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 1.05A 4oguA-3ts7A:
24.5		 4oguA-3ts7A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 11 LEU A  85
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 0.87A 4p0wA-3ts7A:
24.9		 4p0wA-3ts7A:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 11 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.86A 4p0wA-3ts7A:
24.9		 4p0wA-3ts7A:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ARG A  99
GLN A 162
LYS A 185
 None
 1.44A 4q23A-3ts7A:
24.3		 4q23A-3ts7A:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
GLN A 162
LYS A 185
 None
 1.06A 4q23A-3ts7A:
24.3		 4q23A-3ts7A:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ARG A  99
GLN A 162
THR A 186
 None
 1.36A 4rxdA-3ts7A:
7.4		 4rxdA-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ARG A  99
LYS A 185
THR A 186
 None
 0.98A 4rxdA-3ts7A:
7.4		 4rxdA-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 0.90A 4rxdA-3ts7A:
7.4		 4rxdA-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.70A 4rxdA-3ts7A:
7.4		 4rxdA-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ARG A  99
GLN A 162
THR A 186
 None
 1.34A 4rxdB-3ts7A:
24.1		 4rxdB-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ARG A  99
LYS A 185
THR A 186
 None
 0.98A 4rxdB-3ts7A:
24.1		 4rxdB-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 0.89A 4rxdB-3ts7A:
24.1		 4rxdB-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.71A 4rxdB-3ts7A:
24.1		 4rxdB-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ARG A  99
GLN A 162
THR A 186
 None
 1.35A 4rxdC-3ts7A:
24.2		 4rxdC-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  88
ARG A  99
LYS A 185
THR A 186
 None
 0.98A 4rxdC-3ts7A:
24.2		 4rxdC-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 0.90A 4rxdC-3ts7A:
24.2		 4rxdC-3ts7A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  85
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 0.70A 4rxdC-3ts7A:
24.2		 4rxdC-3ts7A:
24.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 8 ASP A  88
ASP A  94
ARG A  99
GLN A 162
LYS A 185
 None
 1.22A 4umjA-3ts7A:
38.0		 4umjA-3ts7A:
57.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 8 LEU A  85
ASP A  88
ASP A  94
ARG A  99
GLN A 162
 None
 1.08A 4umjA-3ts7A:
38.0		 4umjA-3ts7A:
57.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 8 SER A  84
ASP A  94
ARG A  99
MET A 158
GLN A 162
LYS A 185
 None
 0.71A 4umjA-3ts7A:
38.0		 4umjA-3ts7A:
57.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 8 SER A  84
LEU A  85
ASP A  94
ARG A  99
MET A 158
GLN A 162
 None
 0.45A 4umjA-3ts7A:
38.0		 4umjA-3ts7A:
57.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		7 / 9 LEU A  85
ASP A  88
ASP A  94
ARG A  99
GLN A 162
LYS A 185
THR A 186
 None
 1.09A 4umjB-3ts7A:
38.3		 4umjB-3ts7A:
57.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		8 / 9 SER A  84
LEU A  85
ASP A  94
ARG A  99
MET A 158
GLN A 162
LYS A 185
THR A 186
 None
 0.70A 4umjB-3ts7A:
38.3		 4umjB-3ts7A:
57.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		4 / 6 HIS A  81
GLY A  48
GLU A  78
ARG A  50
 PO4  A 324 ( 3.9A)
PO4  A 324 (-3.5A)
PO4  A 324 ( 4.9A)
None
 1.03A 4zbqA-3ts7A:
3.5		 4zbqA-3ts7A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 12 LEU A  85
ASP A  88
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 1.21A 5cg5A-3ts7A:
24.1		 5cg5A-3ts7A:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 12 LEU A  85
ASP A  88
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 1.02A 5cg5A-3ts7A:
24.1		 5cg5A-3ts7A:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 12 LEU A  85
ASP A  88
ASP A  94
ARG A  99
GLN A 162
THR A 186
 None
 1.21A 5cg6A-3ts7A:
24.7		 5cg6A-3ts7A:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		6 / 12 LEU A  85
ASP A  88
ASP A  94
ARG A  99
LYS A 185
THR A 186
 None
 1.01A 5cg6A-3ts7A:
24.7		 5cg6A-3ts7A:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		3 / 3 ASP A 227
LEU A  85
ARG A  99
 None
 0.60A 5e8qA-3ts7A:
undetectable		 5e8qA-3ts7A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 ASP A  88
ASP A  89
ASP A  94
ARG A  99
LYS A 185
 None
 1.15A 5eroC-3ts7A:
22.6		 5eroC-3ts7A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 GLY A 262
GLY A 259
LEU A 258
LEU A 178
TYR A 254
 None
 1.13A 5hwkA-3ts7A:
undetectable		 5hwkA-3ts7A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		5 / 10 GLY A 262
GLY A 259
LEU A 258
LEU A 178
TYR A 254
 None
 1.14A 5hwkB-3ts7A:
undetectable		 5hwkB-3ts7A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		4 / 6 VAL A  44
LEU A 121
LEU A 124
LEU A  36
 None
 1.05A 6f6sA-3ts7A:
undetectable
6f6sB-3ts7A:
undetectable		 6f6sA-3ts7A:
15.33
6f6sB-3ts7A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		4 / 7 LEU A  85
ASP A  94
ARG A  99
GLN A 162
 None
 0.67A 6g31D-3ts7A:
21.7		 6g31D-3ts7A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		4 / 6 LEU A  85
ASP A  88
ARG A  99
GLN A 162
 None
 1.36A 6g31J-3ts7A:
22.5		 6g31J-3ts7A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3ts7 GERANYLTRANSTRANSFER
ASE
(Methylococcus
capsulatus) 		4 / 6 LEU A  85
ASP A  94
ARG A  99
GLN A 162
 None
 0.73A 6g31J-3ts7A:
22.5		 6g31J-3ts7A:
15.81