SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ts9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 3ts9 INTERFERON-INDUCED
HELICASE C
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 6 ILE A  80
TYR A  83
PHE A  10
PHE A 121
 None
 1.38A 1e73M-3ts9A:
undetectable		 1e73M-3ts9A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ts9 INTERFERON-INDUCED
HELICASE C
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 5 MET A  18
LEU A  15
PRO A  29
SER A  28
 None
 1.39A 4kmmB-3ts9A:
undetectable		 4kmmB-3ts9A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 3ts9 INTERFERON-INDUCED
HELICASE C
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		5 / 11 ILE A  17
HIS A  63
LEU A  64
LEU A 117
LEU A  86
 None
 1.09A 4p65E-3ts9A:
undetectable
4p65F-3ts9A:
undetectable
4p65J-3ts9A:
undetectable
4p65L-3ts9A:
undetectable		 4p65E-3ts9A:
6.57
4p65F-3ts9A:
19.75
4p65J-3ts9A:
19.75
4p65L-3ts9A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_I_IPHI101_0
(INSULIN)		 3ts9 INTERFERON-INDUCED
HELICASE C
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		5 / 12 LEU A 117
LEU A  86
ILE A  17
HIS A  63
LEU A  64
 None
 0.99A 4p65B-3ts9A:
undetectable
4p65D-3ts9A:
undetectable
4p65I-3ts9A:
undetectable
4p65J-3ts9A:
undetectable		 4p65B-3ts9A:
19.75
4p65D-3ts9A:
19.75
4p65I-3ts9A:
6.57
4p65J-3ts9A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)		 3ts9 INTERFERON-INDUCED
HELICASE C
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		5 / 12 LEU A  86
LEU A 117
ILE A  17
HIS A  63
LEU A  64
 None
 0.99A 4p65F-3ts9A:
undetectable
4p65H-3ts9A:
undetectable
4p65K-3ts9A:
undetectable
4p65L-3ts9A:
undetectable		 4p65F-3ts9A:
19.75
4p65H-3ts9A:
19.75
4p65K-3ts9A:
6.57
4p65L-3ts9A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ts9 INTERFERON-INDUCED
HELICASE C
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 7 LYS A 125
LEU A 128
PHE A  10
LEU A  14
 None
 0.84A 5b3sP-3ts9A:
undetectable		 5b3sP-3ts9A:
16.39