SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tsn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 11 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.86A 1c6yA-3tsnA:
undetectable		 1c6yA-3tsnA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.94A 1c6zA-3tsnA:
undetectable		 1c6zA-3tsnA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.90A 1c6zB-3tsnA:
undetectable		 1c6zB-3tsnA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		4 / 6 VAL A 171
GLY A 172
ALA A 304
LEU A 308
 None
 0.74A 1e7bB-3tsnA:
undetectable		 1e7bB-3tsnA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 11 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.95A 1n49C-3tsnA:
undetectable		 1n49C-3tsnA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		4 / 7 LEU A 164
VAL A 171
GLY A 172
ASP A 302
 None
 0.61A 1p2yA-3tsnA:
undetectable		 1p2yA-3tsnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 10 GLY A 172
VAL A 171
LEU A 308
LEU A 305
ALA A 298
 None
None
None
UNL  A 601 ( 4.5A)
None
 1.27A 1pbcA-3tsnA:
3.0		 1pbcA-3tsnA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		4 / 7 LEU A 164
VAL A 171
GLY A 172
ASP A 302
 None
 0.78A 1t88A-3tsnA:
undetectable		 1t88A-3tsnA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		4 / 4 SER A   7
ILE A   6
VAL A 330
THR A 334
 None
 1.05A 1u70A-3tsnA:
undetectable		 1u70A-3tsnA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.87A 2hs1A-3tsnA:
undetectable		 2hs1A-3tsnA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.97A 2nmyB-3tsnA:
undetectable		 2nmyB-3tsnA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.90A 2q64A-3tsnA:
undetectable		 2q64A-3tsnA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		3 / 3 TYR A 340
GLU A  17
THR A 334
 None
 0.88A 2y7hB-3tsnA:
undetectable		 2y7hB-3tsnA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZE2_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 10 ASN A  12
TYR A 108
PRO A 132
LEU A  16
TYR A 340
 None
 1.34A 2ze2A-3tsnA:
1.5		 2ze2A-3tsnA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 10 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.90A 3ekpD-3tsnA:
undetectable		 3ekpD-3tsnA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.90A 3ekqA-3tsnA:
undetectable		 3ekqA-3tsnA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 10 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 1.00A 3ekwA-3tsnA:
undetectable		 3ekwA-3tsnA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 11 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.95A 3ekxB-3tsnA:
undetectable		 3ekxB-3tsnA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		4 / 6 ILE A  57
THR A  31
PHE A  68
TYR A  80
 None
 1.30A 3elzB-3tsnA:
undetectable		 3elzB-3tsnA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.91A 3jvyB-3tsnA:
undetectable		 3jvyB-3tsnA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		4 / 8 LEU A 152
ALA A 160
SER A 320
ARG A 327
 None
 1.01A 3kp6A-3tsnA:
undetectable		 3kp6A-3tsnA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 11 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 1.02A 3lzvB-3tsnA:
undetectable		 3lzvB-3tsnA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 9 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.96A 3ndwB-3tsnA:
undetectable		 3ndwB-3tsnA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 10 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 1.00A 3nujA-3tsnA:
undetectable		 3nujA-3tsnA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_1
(PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 9 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 1.06A 3nuoA-3tsnA:
undetectable		 3nuoA-3tsnA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.94A 3oxcA-3tsnA:
undetectable		 3oxcA-3tsnA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		4 / 5 VAL A  20
LEU A  52
LEU A  45
ILE A  36
 None
 0.92A 4a9jA-3tsnA:
undetectable		 4a9jA-3tsnA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		4 / 5 VAL A  20
LEU A  52
LEU A  45
ILE A  36
 None
 0.86A 4a9jB-3tsnA:
undetectable		 4a9jB-3tsnA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		4 / 5 VAL A  20
LEU A  52
LEU A  45
ILE A  36
 None
 0.91A 4a9jC-3tsnA:
undetectable		 4a9jC-3tsnA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 ILE A 358
TYR A  34
LEU A  16
LEU A  41
LEU A 129
 None
 1.35A 4j03A-3tsnA:
undetectable		 4j03A-3tsnA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		4 / 7 VAL A 120
ALA A 116
PHE A  35
TYR A  80
 None
 0.98A 4lb2A-3tsnA:
undetectable		 4lb2A-3tsnA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 11 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.99A 4njtA-3tsnA:
undetectable		 4njtA-3tsnA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 11 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.93A 4njtC-3tsnA:
undetectable		 4njtC-3tsnA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 11 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 0.88A 4qgiB-3tsnA:
undetectable		 4qgiB-3tsnA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 PHE A 199
ILE A 161
PHE A 205
LEU A 360
HIS A 361
 None
 1.31A 5esgA-3tsnA:
undetectable		 5esgA-3tsnA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 9 ALA A  44
ILE A   8
GLY A  15
ILE A  14
ILE A  96
 None
 1.02A 5kr0A-3tsnA:
undetectable		 5kr0A-3tsnA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 ILE A 325
LEU A  86
THR A 130
LEU A 128
PHE A 113
 None
 1.13A 5xxiA-3tsnA:
undetectable		 5xxiA-3tsnA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 9 GLY A  15
TYR A 350
GLU A  17
GLY A   9
PRO A 132
 None
 1.21A 5zniA-3tsnA:
2.4		 5zniA-3tsnA:
10.77