SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tt1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.12A 1usqA-3tt1H:
undetectable		 1usqA-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.80A 1usqB-3tt1H:
undetectable		 1usqB-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.79A 1usqC-3tt1H:
undetectable		 1usqC-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.80A 1usqD-3tt1H:
undetectable		 1usqD-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.80A 1usqE-3tt1H:
undetectable		 1usqE-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.11A 1usqF-3tt1H:
undetectable		 1usqF-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.87A 2jkjA-3tt1H:
undetectable		 2jkjA-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.86A 2jkjB-3tt1H:
undetectable		 2jkjB-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.87A 2jkjC-3tt1H:
undetectable		 2jkjC-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.13A 2jkjE-3tt1H:
undetectable		 2jkjE-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.13A 2jklA-3tt1H:
undetectable		 2jklA-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.86A 2jklB-3tt1H:
undetectable		 2jklB-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.14A 2jklC-3tt1H:
undetectable		 2jklC-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.13A 2jklD-3tt1H:
undetectable		 2jklD-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.13A 2jklE-3tt1H:
undetectable		 2jklE-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.13A 2jklF-3tt1H:
undetectable		 2jklF-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		4 / 5 ILE H  34
PRO H  53
TYR H  52
TYR H  33
 None
 0.98A 3d9lA-3tt1H:
undetectable
3d9lY-3tt1H:
undetectable		 3d9lA-3tt1H:
18.26
3d9lY-3tt1H:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_E_C2FE995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		5 / 11 GLN H   6
GLN H  82
LEU H  20
THR H 115
LEU H  70
 None
 1.47A 3fsuE-3tt1H:
undetectable		 3fsuE-3tt1H:
20.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  98
TYR H 110
 None
 0.28A 4m7kH-3tt1H:
26.1		 4m7kH-3tt1H:
67.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		5 / 12 ALA H  16
PHE H 154
TYR H 153
THR H  41
THR H  87
 None
 1.19A 5tl8A-3tt1H:
undetectable		 5tl8A-3tt1H:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		3 / 3 TYR H  27
ARG H  77
THR H  30
 None
 0.82A 5z84J-3tt1H:
undetectable		 5z84J-3tt1H:
16.13