SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tt3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 3tt3 MOUSE MONOCLONAL
1GG1 FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		4 / 6 ARG H  74
SER H  76
PHE H  29
PRO H  53
 None
 1.49A 3jqaC-3tt3H:
undetectable		 3jqaC-3tt3H:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 3tt3 MOUSE MONOCLONAL
1GG1 FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		4 / 6 ARG H  74
SER H  76
PHE H  29
PRO H  53
 None
 1.49A 3jqaD-3tt3H:
undetectable		 3jqaD-3tt3H:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3tt3 MOUSE MONOCLONAL
1GG1 FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		3 / 3 ARG H  98
HIS H  32
TYR H 108
 None
 1.24A 4fu8A-3tt3H:
undetectable		 4fu8A-3tt3H:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3tt3 MOUSE MONOCLONAL
1GG1 FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		3 / 3 ARG H  98
HIS H  32
TYR H 108
 None
 1.23A 4fu9A-3tt3H:
undetectable		 4fu9A-3tt3H:
21.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 3tt3 MOUSE MONOCLONAL
1GG1 FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		5 / 5 SER H 118
ALA H 120
PHE H 152
LEU H 176
ASP H 179
 None
 0.54A 5mthA-3tt3H:
28.8		 5mthA-3tt3H:
81.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 3tt3 MOUSE MONOCLONAL
1GG1 FAB FRAGMENT,
KAPPA LIGHT CHAIN
(Mus
musculus) 		5 / 12 ALA H  16
PHE H 152
TYR H 151
LEU H 114
THR H  87
 None
 1.16A 5tl8A-3tt3H:
undetectable		 5tl8A-3tt3H:
21.20