SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tu6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3tu6 PSEUDOAZURIN (BLUE
COPPER PROTEIN)
(Sinorhizobium
meliloti) 		4 / 4 HIS A  42
CYH A  80
HIS A  83
MET A  88
 CU  A 201 (-3.1A)
CU  A 201 (-2.2A)
CU  A 201 (-3.1A)
CU  A 201 (-2.5A)
 0.35A 1oe1A-3tu6A:
3.2		 1oe1A-3tu6A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3tu6 PSEUDOAZURIN (BLUE
COPPER PROTEIN)
(Sinorhizobium
meliloti) 		5 / 5 HIS A  42
CYH A  80
PRO A  82
HIS A  83
MET A  88
 CU  A 201 (-3.1A)
CU  A 201 (-2.2A)
None
CU  A 201 (-3.1A)
CU  A 201 (-2.5A)
 0.82A 1oe2A-3tu6A:
5.3		 1oe2A-3tu6A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3tu6 PSEUDOAZURIN (BLUE
COPPER PROTEIN)
(Sinorhizobium
meliloti) 		4 / 4 HIS A  42
CYH A  80
HIS A  83
MET A  88
 CU  A 201 (-3.1A)
CU  A 201 (-2.2A)
CU  A 201 (-3.1A)
CU  A 201 (-2.5A)
 0.37A 1oe3A-3tu6A:
undetectable		 1oe3A-3tu6A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 3tu6 PSEUDOAZURIN (BLUE
COPPER PROTEIN)
(Sinorhizobium
meliloti) 		5 / 10 TYR A  76
ALA A  51
TYR A  78
ILE A 123
ILE A 119
 None
 1.31A 2dm6A-3tu6A:
undetectable
2dm6B-3tu6A:
undetectable		 2dm6A-3tu6A:
19.82
2dm6B-3tu6A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3tu6 PSEUDOAZURIN (BLUE
COPPER PROTEIN)
(Sinorhizobium
meliloti) 		4 / 4 HIS A  42
CYH A  80
HIS A  83
MET A  88
 CU  A 201 (-3.1A)
CU  A 201 (-2.2A)
CU  A 201 (-3.1A)
CU  A 201 (-2.5A)
 0.49A 2fqdA-3tu6A:
undetectable		 2fqdA-3tu6A:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3tu6 PSEUDOAZURIN (BLUE
COPPER PROTEIN)
(Sinorhizobium
meliloti) 		4 / 4 HIS A  42
CYH A  80
HIS A  83
MET A  88
 CU  A 201 (-3.1A)
CU  A 201 (-2.2A)
CU  A 201 (-3.1A)
CU  A 201 (-2.5A)
 0.45A 2fqeA-3tu6A:
undetectable		 2fqeA-3tu6A:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3tu6 PSEUDOAZURIN (BLUE
COPPER PROTEIN)
(Sinorhizobium
meliloti) 		4 / 4 HIS A  42
CYH A  80
HIS A  83
MET A  88
 CU  A 201 (-3.1A)
CU  A 201 (-2.2A)
CU  A 201 (-3.1A)
CU  A 201 (-2.5A)
 0.43A 2fqfA-3tu6A:
undetectable		 2fqfA-3tu6A:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3tu6 PSEUDOAZURIN (BLUE
COPPER PROTEIN)
(Sinorhizobium
meliloti) 		4 / 4 HIS A  42
CYH A  80
HIS A  83
MET A  88
 CU  A 201 (-3.1A)
CU  A 201 (-2.2A)
CU  A 201 (-3.1A)
CU  A 201 (-2.5A)
 0.42A 2fqgA-3tu6A:
undetectable		 2fqgA-3tu6A:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3tu6 PSEUDOAZURIN (BLUE
COPPER PROTEIN)
(Sinorhizobium
meliloti) 		4 / 4 HIS A  42
CYH A  80
HIS A  83
MET A  88
 CU  A 201 (-3.1A)
CU  A 201 (-2.2A)
CU  A 201 (-3.1A)
CU  A 201 (-2.5A)
 0.37A 2xxgA-3tu6A:
5.0		 2xxgA-3tu6A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3tu6 PSEUDOAZURIN (BLUE
COPPER PROTEIN)
(Sinorhizobium
meliloti) 		5 / 5 HIS A  42
CYH A  80
PRO A  82
HIS A  83
MET A  88
 CU  A 201 (-3.1A)
CU  A 201 (-2.2A)
None
CU  A 201 (-3.1A)
CU  A 201 (-2.5A)
 0.87A 2xxgC-3tu6A:
5.1		 2xxgC-3tu6A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 3tu6 PSEUDOAZURIN (BLUE
COPPER PROTEIN)
(Sinorhizobium
meliloti) 		4 / 4 HIS A  42
CYH A  80
HIS A  83
MET A  88
 CU  A 201 (-3.1A)
CU  A 201 (-2.2A)
CU  A 201 (-3.1A)
CU  A 201 (-2.5A)
 0.40A 4ef3A-3tu6A:
undetectable		 4ef3A-3tu6A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3tu6 PSEUDOAZURIN (BLUE
COPPER PROTEIN)
(Sinorhizobium
meliloti) 		5 / 12 TYR A 108
GLY A  90
LEU A  46
SER A 112
ILE A  92
 None
 1.13A 4qtuB-3tu6A:
undetectable		 4qtuB-3tu6A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3tu6 PSEUDOAZURIN (BLUE
COPPER PROTEIN)
(Sinorhizobium
meliloti) 		5 / 12 GLY A  90
TYR A  76
SER A 112
ALA A  19
ALA A  23
 None
 1.29A 4ymgA-3tu6A:
undetectable		 4ymgA-3tu6A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 3tu6 PSEUDOAZURIN (BLUE
COPPER PROTEIN)
(Sinorhizobium
meliloti) 		5 / 12 VAL A  33
GLY A  50
VAL A 103
PRO A  97
GLY A  95
 None
 1.12A 6brdC-3tu6A:
undetectable		 6brdC-3tu6A:
19.20