SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tuf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)		 3tuf STAGE III
SPORULATION PROTEIN
AH
(Bacillus
subtilis) 		4 / 5 TYR A 109
ALA A 211
ALA A 170
TYR A 167
 None
 1.17A 3d91A-3tufA:
undetectable		 3d91A-3tufA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 3tuf STAGE III
SPORULATION PROTEIN
AH
(Bacillus
subtilis) 		4 / 7 LEU A 161
ILE A 179
ILE A 181
VAL A 172
 None
 0.80A 4ojbA-3tufA:
undetectable		 4ojbA-3tufA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3tuf STAGE III
SPORULATION PROTEIN
AH
(Bacillus
subtilis) 		5 / 12 VAL A 151
GLU A 152
ALA A 147
ARG A 117
LEU A 124
 None
 1.47A 5m54B-3tufA:
undetectable		 5m54B-3tufA:
20.17