SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3tul CELL INVASION
PROTEIN SIPB
(Salmonella
enterica) 		5 / 9 ALA A 205
THR A 206
ALA A 208
VAL A 156
ALA A 201
 None
 1.16A 4qvnK-3tulA:
undetectable
4qvnL-3tulA:
undetectable		 4qvnK-3tulA:
21.36
4qvnL-3tulA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3tul CELL INVASION
PROTEIN SIPB
(Salmonella
enterica) 		5 / 9 ALA A 205
THR A 206
ALA A 208
VAL A 156
ALA A 201
 None
 1.16A 4qvnY-3tulA:
undetectable
4qvnZ-3tulA:
undetectable		 4qvnY-3tulA:
21.36
4qvnZ-3tulA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 3tul CELL INVASION
PROTEIN SIPB
(Salmonella
enterica) 		4 / 7 GLN A 130
LEU A 133
ALA A 139
LEU A 142
 None
 1.07A 5nwvA-3tulA:
undetectable		 5nwvA-3tulA:
9.62