SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tvt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3tvt DISKS LARGE 1 TUMOR
SUPPRESSOR PROTEIN
(Drosophila
melanogaster) 		4 / 7 TYR A 952
VAL A 788
ILE A 878
GLU A 805
 None
 0.97A 1j96B-3tvtA:
undetectable		 1j96B-3tvtA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 3tvt DISKS LARGE 1 TUMOR
SUPPRESSOR PROTEIN
(Drosophila
melanogaster) 		3 / 3 ALA A 776
VAL A 969
TRP A 968
 None
 0.87A 1jo3A-3tvtA:
undetectable		 1jo3A-3tvtA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 3tvt DISKS LARGE 1 TUMOR
SUPPRESSOR PROTEIN
(Drosophila
melanogaster) 		3 / 3 ALA A 776
VAL A 969
TRP A 968
 None
 0.88A 1jo3B-3tvtA:
undetectable		 1jo3B-3tvtA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 3tvt DISKS LARGE 1 TUMOR
SUPPRESSOR PROTEIN
(Drosophila
melanogaster) 		3 / 3 ALA A 776
VAL A 969
TRP A 968
 None
 0.93A 1jo4A-3tvtA:
undetectable		 1jo4A-3tvtA:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 3tvt DISKS LARGE 1 TUMOR
SUPPRESSOR PROTEIN
(Drosophila
melanogaster) 		3 / 3 ALA A 776
VAL A 969
TRP A 968
 None
 0.93A 1jo4B-3tvtA:
undetectable		 1jo4B-3tvtA:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 3tvt DISKS LARGE 1 TUMOR
SUPPRESSOR PROTEIN
(Drosophila
melanogaster) 		3 / 3 ALA A 898
VAL A 897
GLN A 962
 None
 0.41A 3of4B-3tvtA:
undetectable		 3of4B-3tvtA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 3tvt DISKS LARGE 1 TUMOR
SUPPRESSOR PROTEIN
(Drosophila
melanogaster) 		4 / 7 PRO A 787
ARG A 786
GLY A 964
PRO A 965
 None
 1.37A 3ucbB-3tvtA:
undetectable		 3ucbB-3tvtA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 3tvt DISKS LARGE 1 TUMOR
SUPPRESSOR PROTEIN
(Drosophila
melanogaster) 		5 / 12 GLU A 851
GLY A 883
SER A 882
LEU A 879
LEU A 894
 None
 1.19A 5w7pA-3tvtA:
undetectable		 5w7pA-3tvtA:
19.82