SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tw5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		3 / 3 ARG A 438
ILE A 442
TRP A 441
 None
 1.06A 1m8eB-3tw5A:
undetectable		 1m8eB-3tw5A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		5 / 12 ILE A 457
GLY A 201
ALA A 321
SER A 324
TRP A 215
 None
 1.36A 1nbhA-3tw5A:
undetectable		 1nbhA-3tw5A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		5 / 12 ILE A 457
GLY A 201
ALA A 321
SER A 324
TRP A 215
 None
 1.35A 1nbhD-3tw5A:
undetectable		 1nbhD-3tw5A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		3 / 3 ARG A 438
ILE A 442
TRP A 441
 None
 0.96A 1nodB-3tw5A:
undetectable		 1nodB-3tw5A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		3 / 3 ARG A 438
ILE A 442
TRP A 441
 None
 1.07A 1qomA-3tw5A:
undetectable		 1qomA-3tw5A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		4 / 4 HIS A 491
ASP A 169
ASN A 167
ASP A 361
 None
 1.38A 1wg8A-3tw5A:
undetectable		 1wg8A-3tw5A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		5 / 11 VAL A 517
ALA A 321
PRO A 303
ILE A 289
ALA A 296
 None
 1.19A 2admB-3tw5A:
undetectable		 2admB-3tw5A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		3 / 3 ARG A 438
ILE A 442
TRP A 441
 None
 0.93A 2nodB-3tw5A:
undetectable		 2nodB-3tw5A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		3 / 3 ARG A 438
ILE A 442
TRP A 441
 None
 0.97A 3e68A-3tw5A:
undetectable		 3e68A-3tw5A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		3 / 3 ARG A 438
ILE A 442
TRP A 441
 None
 1.01A 3e6tB-3tw5A:
undetectable		 3e6tB-3tw5A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		3 / 3 ARG A 438
ILE A 442
TRP A 441
 None
 1.11A 3e7iB-3tw5A:
undetectable		 3e7iB-3tw5A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		3 / 3 ARG A 438
ILE A 442
TRP A 441
 None
 1.05A 3nw2B-3tw5A:
undetectable		 3nw2B-3tw5A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		3 / 3 ASP A 385
GLU A 391
GLY A 389
 None
 0.56A 3w9tA-3tw5A:
undetectable		 3w9tA-3tw5A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		4 / 7 SER A 249
ASP A 248
GLY A 252
SER A 242
 None
 1.04A 4ac9C-3tw5A:
undetectable		 4ac9C-3tw5A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		4 / 8 ASN A 165
GLU A 477
ILE A 478
ASN A 373
 None
 1.05A 4d33A-3tw5A:
undetectable		 4d33A-3tw5A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		4 / 7 ASN A 165
GLU A 477
ILE A 478
ASN A 373
 None
 1.08A 4d33B-3tw5A:
undetectable		 4d33B-3tw5A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		4 / 8 ASN A 165
GLU A 477
ILE A 478
ASN A 373
 None
 1.09A 4d39A-3tw5A:
undetectable		 4d39A-3tw5A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_D_SAMD800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		5 / 10 ILE A 478
ALA A 365
GLU A 163
GLY A 338
ASN A 165
 None
 1.36A 4e47D-3tw5A:
undetectable		 4e47D-3tw5A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J83_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		5 / 11 ILE A 478
ALA A 365
GLU A 163
GLY A 338
ASN A 165
 None
 1.36A 4j83A-3tw5A:
undetectable		 4j83A-3tw5A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_D_SAMD401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		5 / 11 ILE A 478
ALA A 365
GLU A 163
GLY A 338
ASN A 165
 None
 1.35A 4jdsD-3tw5A:
undetectable		 4jdsD-3tw5A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		5 / 11 ILE A 478
ALA A 365
GLU A 163
GLY A 338
ASN A 165
 None
 1.31A 4jlgB-3tw5A:
undetectable		 4jlgB-3tw5A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		5 / 12 SER A 197
SER A 290
GLU A 444
LEU A 439
THR A 461
 None
 1.44A 4zjlA-3tw5A:
undetectable		 4zjlA-3tw5A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		5 / 12 GLY A 481
TYR A 468
HIS A 368
GLU A 182
ILE A 170
 None
 1.20A 5igwA-3tw5A:
undetectable		 5igwA-3tw5A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 3tw5 TRANSGLUTAMINASE
ELICITOR
(Phytophthora
sojae) 		5 / 12 TYR A 468
LEU A 185
HIS A 368
LEU A 472
GLU A 404
 None
None
None
None
CXS  A   1 (-2.8A)
 1.15A 5v0vA-3tw5A:
undetectable		 5v0vA-3tw5A:
21.72