SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tx3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MOG_A_RBFA200_1 (DODECIN)	3tx3	UNCHARACTERIZED PROTEIN INVOLVED IN CYSTEINE BIOSYNTHESIS (Idiomarina loihiensis)	3 / 3	PHE A 183 TRP A 236 GLU A 110	None	0.81A	1mogA-3tx3A: undetectable	1mogA-3tx3A: 13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PXX_B_DIFB1701_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3tx3	UNCHARACTERIZED PROTEIN INVOLVED IN CYSTEINE BIOSYNTHESIS (Idiomarina loihiensis)	5 / 9	VAL A 211 LEU A 20 VAL A 229 GLY A 231 ALA A 232	None	1.27A	1pxxB-3tx3A: undetectable	1pxxB-3tx3A: 17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_E_SORE1341_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3tx3	UNCHARACTERIZED PROTEIN INVOLVED IN CYSTEINE BIOSYNTHESIS (Idiomarina loihiensis)	4 / 7	ILE A 14 LEU A 11 GLY A 208 GLY A 210	None	0.86A	5a06E-3tx3A: undetectable	5a06E-3tx3A: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B8K_A_W9TA300_0 (GALECTIN-3)	3tx3	UNCHARACTERIZED PROTEIN INVOLVED IN CYSTEINE BIOSYNTHESIS (Idiomarina loihiensis)	4 / 7	HIS A 186 ASN A 185 GLU A 107 ARG A 111	None	1.29A	6b8kA-3tx3A: undetectable	6b8kA-3tx3A: 14.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MOG_A_RBFA200_1","DODECIN","3tx3","UNCHARACTERIZED PROTEIN INVOLVED IN CYSTEINE BIOSYNTHESIS","Idiomarina loihiensis",3,"PHE A 183;TRP A 236;GLU A 110","None","0.81A","1mogA-3tx3A:undetectable","1mogA-3tx3A:13.47"],["1PXX_B_DIFB1701_1","PROSTAGLANDIN G\/H SYNTHASE 2","3tx3","UNCHARACTERIZED PROTEIN INVOLVED IN CYSTEINE BIOSYNTHESIS","Idiomarina loihiensis",5,"VAL A 211;LEU A  20;VAL A 229;GLY A 231;ALA A 232","None","1.27A","1pxxB-3tx3A:undetectable","1pxxB-3tx3A:17.85"],["5A06_E_SORE1341_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3tx3","UNCHARACTERIZED PROTEIN INVOLVED IN CYSTEINE BIOSYNTHESIS","Idiomarina loihiensis",4,"ILE A  14;LEU A  11;GLY A 208;GLY A 210","None","0.86A","5a06E-3tx3A:undetectable","5a06E-3tx3A:19.55"],["6B8K_A_W9TA300_0","GALECTIN-3","3tx3","UNCHARACTERIZED PROTEIN INVOLVED IN CYSTEINE BIOSYNTHESIS","Idiomarina loihiensis",4,"HIS A 186;ASN A 185;GLU A 107;ARG A 111","None","1.29A","6b8kA-3tx3A:undetectable","6b8kA-3tx3A:14.77"]]