SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tx8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 276
VAL A 183
ILE A 181
LEU A 231
VAL A 212
 None
 1.12A 1cqpA-3tx8A:
3.2
1cqpB-3tx8A:
2.2		 1cqpA-3tx8A:
19.95
1cqpB-3tx8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 9 ALA A  42
LEU A  43
LEU A  48
HIS A 113
LEU A  18
 None
 1.50A 1ereA-3tx8A:
undetectable		 1ereA-3tx8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 9 ALA A  42
LEU A  43
LEU A  48
HIS A 113
LEU A  18
 None
 1.49A 1ereC-3tx8A:
undetectable		 1ereC-3tx8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 9 ALA A  42
LEU A  43
LEU A  48
HIS A 113
LEU A  18
 None
 1.48A 1ereD-3tx8A:
undetectable		 1ereD-3tx8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 10 ALA A  42
LEU A  43
LEU A  48
HIS A 113
LEU A  18
 None
 1.49A 1pcgB-3tx8A:
undetectable		 1pcgB-3tx8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 10 ALA A  42
LEU A  43
LEU A  48
HIS A 113
LEU A  18
 None
 1.45A 1qkuA-3tx8A:
undetectable		 1qkuA-3tx8A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 10 ALA A  42
LEU A  43
LEU A  48
HIS A 113
LEU A  18
 None
 1.46A 1qkuB-3tx8A:
undetectable		 1qkuB-3tx8A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 10 ALA A  42
LEU A  43
LEU A  48
HIS A 113
LEU A  18
 None
 1.46A 1qkuC-3tx8A:
undetectable		 1qkuC-3tx8A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 7 PRO A 166
GLY A 337
THR A  19
ILE A 356
GLY A 107
 None
 1.24A 1usqF-3tx8A:
undetectable		 1usqF-3tx8A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 8 GLU A 165
HIS A  77
ASP A 103
GLU A 137
 None
 0.76A 1v7zA-3tx8A:
4.3		 1v7zA-3tx8A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 8 GLU A 165
HIS A  77
ASP A 103
GLU A 137
 None
 0.76A 1v7zB-3tx8A:
4.4		 1v7zB-3tx8A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 8 GLU A 165
HIS A  77
ASP A 103
GLU A 137
 None
 0.77A 1v7zC-3tx8A:
4.3		 1v7zC-3tx8A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 8 GLU A 165
HIS A  77
ASP A 103
GLU A 137
 None
 0.77A 1v7zD-3tx8A:
4.4		 1v7zD-3tx8A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 8 GLU A 165
HIS A  77
ASP A 103
GLU A 137
 None
 0.77A 1v7zE-3tx8A:
4.4		 1v7zE-3tx8A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 8 GLU A 165
HIS A  77
ASP A 103
GLU A 137
 None
 0.77A 1v7zF-3tx8A:
4.3		 1v7zF-3tx8A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		3 / 3 THR A  19
GLU A 349
HIS A  77
 None
 0.84A 1xwfB-3tx8A:
undetectable		 1xwfB-3tx8A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		3 / 3 THR A  19
GLU A 349
HIS A  77
 None
 0.82A 1xwfC-3tx8A:
undetectable		 1xwfC-3tx8A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		3 / 3 THR A  19
GLU A 349
HIS A  77
 None
 0.82A 1xwfD-3tx8A:
undetectable		 1xwfD-3tx8A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 5 LEU A 108
LEU A 130
LEU A  61
LEU A 112
 None
 1.15A 1yajD-3tx8A:
undetectable		 1yajD-3tx8A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 12 VAL A  72
LEU A 160
LEU A  74
GLY A 304
LEU A 367
 None
 1.06A 2aylA-3tx8A:
undetectable		 2aylA-3tx8A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 7 PRO A 166
GLY A 337
THR A  19
ILE A 356
GLY A 107
 None
 1.23A 2jkjE-3tx8A:
undetectable		 2jkjE-3tx8A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 7 PRO A 166
GLY A 337
THR A  19
ILE A 356
GLY A 107
 None
 1.22A 2jklE-3tx8A:
undetectable		 2jklE-3tx8A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 7 VAL A 323
ALA A 333
PRO A 166
THR A 167
 None
 1.03A 2q6oA-3tx8A:
undetectable		 2q6oA-3tx8A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 12 GLY A 339
GLY A 164
GLU A 165
THR A 302
ILE A 171
 None
 0.89A 2wa2B-3tx8A:
undetectable		 2wa2B-3tx8A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		3 / 3 VAL A 286
ASN A 178
TRP A 320
 None
PO4  A 401 ( 4.8A)
None
 1.11A 2y00B-3tx8A:
undetectable		 2y00B-3tx8A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 8 GLU A 165
HIS A  77
ASP A 103
GLU A 137
 None
 0.78A 3a6jA-3tx8A:
4.3		 3a6jA-3tx8A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 7 GLU A 165
HIS A  77
ASP A 103
GLU A 137
 None
 0.75A 3a6jB-3tx8A:
4.1		 3a6jB-3tx8A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 8 GLU A 165
HIS A  77
ASP A 103
GLU A 137
 None
 0.75A 3a6jC-3tx8A:
4.0		 3a6jC-3tx8A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 8 GLU A 165
HIS A  77
ASP A 103
GLU A 137
 None
 0.78A 3a6jE-3tx8A:
4.1		 3a6jE-3tx8A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 8 GLU A 165
HIS A  77
ASP A 103
GLU A 137
 None
 0.76A 3a6jF-3tx8A:
4.2		 3a6jF-3tx8A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 6 ALA A  42
LEU A  43
ALA A 116
THR A 117
 None
 0.88A 3b6hA-3tx8A:
undetectable		 3b6hA-3tx8A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 6 ALA A  42
LEU A  43
ALA A 116
THR A 117
 None
 0.87A 3b6hB-3tx8A:
undetectable		 3b6hB-3tx8A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 4 LEU A 162
ASP A 358
VAL A 110
THR A 114
 None
 1.30A 3cyxB-3tx8A:
undetectable		 3cyxB-3tx8A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		3 / 3 LEU A 225
GLU A 172
ILE A 171
 None
 0.58A 3czhA-3tx8A:
undetectable		 3czhA-3tx8A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 8 ALA A  84
ILE A  83
ASN A  86
PRO A  28
 None
 0.86A 3fxrA-3tx8A:
undetectable		 3fxrA-3tx8A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		3 / 3 ASP A 288
ARG A 180
ARG A 325
 None
 0.97A 3k37A-3tx8A:
undetectable		 3k37A-3tx8A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M8P_A_65BA562_0
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 11 LEU A 297
VAL A 309
TYR A 366
PHE A 336
LEU A 334
 None
 1.36A 3m8pA-3tx8A:
4.0
3m8pB-3tx8A:
3.0		 3m8pA-3tx8A:
20.25
3m8pB-3tx8A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_B_ESTB600_1
(ESTROGEN RECEPTOR)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 10 ALA A  42
LEU A  43
LEU A  48
HIS A 113
LEU A  18
 None
 1.48A 3uudB-3tx8A:
undetectable		 3uudB-3tx8A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 12 GLN A 365
ASP A 358
ILE A 362
ALA A 308
VAL A 309
 None
 1.08A 4dx5B-3tx8A:
4.7		 4dx5B-3tx8A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_D_15UD402_1
(PROTHROMBIN)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A  22
ILE A 356
ALA A  75
ALA A 132
GLY A 164
 None
 0.93A 4hfpD-3tx8A:
undetectable		 4hfpD-3tx8A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 11 GLY A 291
ALA A 266
LEU A 179
GLY A 289
ILE A 209
 None
 1.11A 4kt0A-3tx8A:
undetectable
4kt0J-3tx8A:
undetectable		 4kt0A-3tx8A:
19.53
4kt0J-3tx8A:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 12 GLY A  98
ASN A  86
ASP A  24
ILE A  95
GLN A 350
 None
 1.16A 4pooB-3tx8A:
undetectable		 4pooB-3tx8A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		7 / 11 HIS A  77
ASP A 103
GLU A 136
GLU A 137
GLU A 165
GLY A 319
HIS A 345
 None
None
None
None
None
PO4  A 401 (-4.1A)
None
 0.92A 4pqaA-3tx8A:
32.8		 4pqaA-3tx8A:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 12 VAL A 270
LEU A 274
MET A 251
VAL A 183
LEU A 179
 None
 1.13A 4rrwA-3tx8A:
undetectable		 4rrwA-3tx8A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 12 VAL A 270
LEU A 274
MET A 251
VAL A 183
LEU A 179
 None
 1.13A 4rrwB-3tx8A:
undetectable		 4rrwB-3tx8A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 12 VAL A 270
LEU A 274
MET A 251
VAL A 183
LEU A 179
 None
 1.13A 4rrzA-3tx8A:
undetectable		 4rrzA-3tx8A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 12 VAL A 270
LEU A 274
MET A 251
VAL A 183
LEU A 179
 None
 1.13A 4rrzB-3tx8A:
undetectable		 4rrzB-3tx8A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 9 VAL A  72
LEU A 160
LEU A  74
GLY A 304
LEU A 367
 None
 1.10A 4rs0A-3tx8A:
undetectable		 4rs0A-3tx8A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 12 GLN A 365
ASP A 358
ILE A 362
ALA A 308
VAL A 309
 None
 1.10A 4u8vB-3tx8A:
6.5		 4u8vB-3tx8A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A 112
THR A  64
ALA A  62
VAL A  60
ALA A 132
 None
 1.16A 4x1kD-3tx8A:
2.7		 4x1kD-3tx8A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 5 LEU A 163
GLY A 164
ASP A  79
ILE A  78
 None
 1.01A 5ik1A-3tx8A:
undetectable		 5ik1A-3tx8A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 12 GLY A 337
THR A 167
GLY A 168
THR A  19
LEU A  18
 None
 1.15A 5ybbA-3tx8A:
undetectable		 5ybbA-3tx8A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 12 GLY A 337
THR A 167
GLY A 169
THR A  19
LEU A  18
 None
 1.02A 5ybbA-3tx8A:
undetectable		 5ybbA-3tx8A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		5 / 12 GLY A 337
THR A 167
GLY A 169
THR A  19
LEU A  22
 None
 0.95A 5ybbA-3tx8A:
undetectable		 5ybbA-3tx8A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Corynebacterium
glutamicum) 		4 / 6 PHE A 257
ILE A 267
ASN A 264
ASP A 262
 None
 1.36A 6dhbA-3tx8A:
undetectable		 6dhbA-3tx8A:
14.60