SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3txv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 8 GLU A  35
LEU A 296
ALA A 299
LEU A 300
 None
 0.93A 1hwiD-3txvA:
undetectable		 1hwiD-3txvA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A  96
GLY A  93
GLY A  92
LEU A  49
ILE A 174
 None
 0.90A 1mx1D-3txvA:
undetectable		 1mx1D-3txvA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 5 HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.09A 1os2A-3txvA:
undetectable		 1os2A-3txvA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 4 HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.08A 1os2D-3txvA:
undetectable		 1os2D-3txvA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		5 / 10 ALA A 200
HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.16A 1r55A-3txvA:
undetectable		 1r55A-3txvA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 4 HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.11A 1uttA-3txvA:
undetectable		 1uttA-3txvA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 4 HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.09A 1utzA-3txvA:
undetectable		 1utzA-3txvA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 4 HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.10A 1utzB-3txvA:
undetectable		 1utzB-3txvA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 4 HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.09A 2hu6A-3txvA:
undetectable		 2hu6A-3txvA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 4 HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.07A 2ow9B-3txvA:
undetectable		 2ow9B-3txvA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 4 HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.08A 2ozrC-3txvA:
undetectable		 2ozrC-3txvA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 4 HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.06A 2ozrD-3txvA:
undetectable		 2ozrD-3txvA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 4 HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.08A 2ozrE-3txvA:
undetectable		 2ozrE-3txvA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 6 THR A 132
LEU A 143
GLU A 139
CYH A 136
 None
 1.08A 3b6rB-3txvA:
undetectable		 3b6rB-3txvA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 300
ILE A  50
LEU A 292
VAL A 415
MET A  66
 None
 1.03A 3gwxB-3txvA:
undetectable		 3gwxB-3txvA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 5 HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.09A 3likA-3txvA:
undetectable		 3likA-3txvA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 4 HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.10A 3lilA-3txvA:
undetectable		 3lilA-3txvA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 5 HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.08A 3lkaA-3txvA:
undetectable		 3lkaA-3txvA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 7 GLY A 289
VAL A 288
ILE A  50
PHE A  71
 None
 0.83A 4fglC-3txvA:
undetectable		 4fglC-3txvA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		5 / 10 LEU A 410
LEU A 303
LEU A 373
ILE A 387
THR A 318
 None
 1.27A 4mk4A-3txvA:
undetectable		 4mk4A-3txvA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 289
GLY A 291
ASP A  94
THR A  64
ALA A  29
 None
 1.15A 4uckB-3txvA:
undetectable		 4uckB-3txvA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		3 / 3 LEU A  49
PHE A 423
ILE A  26
 None
 0.70A 5dzk1-3txvA:
undetectable
5dzkF-3txvA:
undetectable
5dzkM-3txvA:
undetectable		 5dzk1-3txvA:
2.20
5dzkF-3txvA:
19.38
5dzkM-3txvA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 8 PRO A  98
MET A 134
LEU A  96
LEU A 155
 None
 1.05A 5dzkF-3txvA:
undetectable
5dzkT-3txvA:
undetectable		 5dzkF-3txvA:
19.38
5dzkT-3txvA:
2.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 4 HIS A 265
GLU A 178
HIS A  95
HIS A 129
 None
 1.11A 5n5jA-3txvA:
undetectable		 5n5jA-3txvA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		4 / 6 ARG A 151
ARG A 154
ALA A 113
PRO A  98
 None
 1.28A 5odqA-3txvA:
undetectable		 5odqA-3txvA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE
(Sinorhizobium
meliloti) 		5 / 12 VAL A  33
PHE A  74
ILE A  34
ILE A  50
CYH A  27
 None
 1.36A 6gsdA-3txvA:
3.5		 6gsdA-3txvA:
11.03