SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3txx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.22A 1c9sM-3txxA:
undetectable
1c9sN-3txxA:
undetectable		 1c9sM-3txxA:
11.21
1c9sN-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.19A 1c9sS-3txxA:
undetectable
1c9sT-3txxA:
undetectable		 1c9sS-3txxA:
11.21
1c9sT-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.20A 1gtfA-3txxA:
undetectable
1gtfB-3txxA:
undetectable		 1gtfA-3txxA:
11.21
1gtfB-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.19A 1gtfO-3txxA:
undetectable
1gtfP-3txxA:
undetectable		 1gtfO-3txxA:
11.21
1gtfP-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 1gtfT-3txxA:
undetectable
1gtfU-3txxA:
undetectable		 1gtfT-3txxA:
11.21
1gtfU-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 11 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.17A 1gtfU-3txxA:
undetectable
1gtfV-3txxA:
undetectable		 1gtfU-3txxA:
11.21
1gtfV-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.19A 1gtfL-3txxA:
undetectable
1gtfV-3txxA:
undetectable		 1gtfL-3txxA:
11.21
1gtfV-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.22A 1gtnG-3txxA:
undetectable
1gtnH-3txxA:
undetectable		 1gtnG-3txxA:
11.21
1gtnH-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.17A 1gtnL-3txxA:
undetectable
1gtnM-3txxA:
undetectable		 1gtnL-3txxA:
11.21
1gtnM-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 11 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 1gtnM-3txxA:
undetectable
1gtnN-3txxA:
undetectable		 1gtnM-3txxA:
11.21
1gtnN-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 1gtnN-3txxA:
undetectable
1gtnO-3txxA:
undetectable		 1gtnN-3txxA:
11.21
1gtnO-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.22A 1gtnR-3txxA:
undetectable
1gtnS-3txxA:
undetectable		 1gtnR-3txxA:
11.21
1gtnS-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.21A 1gtnS-3txxA:
undetectable
1gtnT-3txxA:
undetectable		 1gtnS-3txxA:
11.21
1gtnT-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 1gtnU-3txxA:
undetectable
1gtnV-3txxA:
undetectable		 1gtnU-3txxA:
11.21
1gtnV-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 11 GLU A  71
PHE A  59
GLY A  70
LEU A 304
PRO A 120
 None
 1.22A 1mjqA-3txxA:
0.5
1mjqB-3txxA:
0.6		 1mjqA-3txxA:
14.48
1mjqB-3txxA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 11 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.19A 1utdM-3txxA:
undetectable
1utdN-3txxA:
undetectable		 1utdM-3txxA:
11.21
1utdN-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.21A 1utdQ-3txxA:
undetectable
1utdR-3txxA:
undetectable		 1utdQ-3txxA:
11.21
1utdR-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 1utdR-3txxA:
undetectable
1utdS-3txxA:
undetectable		 1utdR-3txxA:
11.21
1utdS-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 1utdT-3txxA:
undetectable
1utdU-3txxA:
undetectable		 1utdT-3txxA:
11.21
1utdU-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.17A 1utdU-3txxA:
undetectable
1utdV-3txxA:
undetectable		 1utdU-3txxA:
11.21
1utdV-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		4 / 5 ILE A  99
ARG A 302
MET A  63
THR A  61
 None
 1.38A 3abkN-3txxA:
undetectable
3abkW-3txxA:
undetectable		 3abkN-3txxA:
20.80
3abkW-3txxA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		4 / 5 ILE A 122
ARG A 302
MET A  63
THR A  61
 None
 1.25A 3abkN-3txxA:
undetectable
3abkW-3txxA:
undetectable		 3abkN-3txxA:
20.80
3abkW-3txxA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 12 SER A  58
MET A  46
MET A 101
PHE A  48
LEU A 270
 None
 1.47A 3aocC-3txxA:
undetectable		 3aocC-3txxA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		4 / 6 ALA A 114
ILE A 110
HIS A 107
ASN A 123
 None
 1.15A 3nneG-3txxA:
2.1		 3nneG-3txxA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		4 / 4 LEU A 169
LEU A 138
GLN A 164
GLU A   9
 None
 1.16A 4i41A-3txxA:
undetectable		 4i41A-3txxA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 12 ALA A  62
ALA A  29
ILE A  30
ASN A 310
GLY A  67
 None
 1.23A 4r38A-3txxA:
undetectable		 4r38A-3txxA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 12 GLN A  50
GLU A 105
ASP A 127
GLY A 124
GLU A 134
 None
 1.16A 4xe5A-3txxA:
undetectable		 4xe5A-3txxA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 12 ILE A 122
GLY A 303
PHE A  59
THR A  55
LEU A  19
 None
 1.17A 5byjA-3txxA:
2.0		 5byjA-3txxA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.18A 5eeuC-3txxA:
undetectable
5eeuD-3txxA:
undetectable		 5eeuC-3txxA:
11.21
5eeuD-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.20A 5eeuG-3txxA:
undetectable
5eeuH-3txxA:
undetectable		 5eeuG-3txxA:
11.21
5eeuH-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5eeuN-3txxA:
undetectable
5eeuO-3txxA:
undetectable		 5eeuN-3txxA:
11.21
5eeuO-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.21A 5eeuP-3txxA:
undetectable
5eeuQ-3txxA:
undetectable		 5eeuP-3txxA:
11.21
5eeuQ-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.20A 5eeuR-3txxA:
undetectable
5eeuS-3txxA:
undetectable		 5eeuR-3txxA:
11.21
5eeuS-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 5eeuS-3txxA:
undetectable
5eeuT-3txxA:
undetectable		 5eeuS-3txxA:
11.21
5eeuT-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.17A 5eeuU-3txxA:
undetectable
5eeuV-3txxA:
undetectable		 5eeuU-3txxA:
11.21
5eeuV-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.18A 5eevC-3txxA:
undetectable
5eevD-3txxA:
undetectable		 5eevC-3txxA:
11.21
5eevD-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.20A 5eevG-3txxA:
undetectable
5eevH-3txxA:
undetectable		 5eevG-3txxA:
11.21
5eevH-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5eevN-3txxA:
undetectable
5eevO-3txxA:
undetectable		 5eevN-3txxA:
11.21
5eevO-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.22A 5eevP-3txxA:
undetectable
5eevQ-3txxA:
undetectable		 5eevP-3txxA:
11.21
5eevQ-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.20A 5eevR-3txxA:
undetectable
5eevS-3txxA:
undetectable		 5eevR-3txxA:
11.21
5eevS-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 5eevS-3txxA:
undetectable
5eevT-3txxA:
undetectable		 5eevS-3txxA:
11.21
5eevT-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5eevU-3txxA:
undetectable
5eevV-3txxA:
undetectable		 5eevU-3txxA:
11.21
5eevV-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.18A 5eewC-3txxA:
undetectable
5eewD-3txxA:
undetectable		 5eewC-3txxA:
11.21
5eewD-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.19A 5eewG-3txxA:
undetectable
5eewH-3txxA:
undetectable		 5eewG-3txxA:
11.21
5eewH-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5eewN-3txxA:
undetectable
5eewO-3txxA:
undetectable		 5eewN-3txxA:
11.21
5eewO-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.21A 5eewP-3txxA:
undetectable
5eewQ-3txxA:
undetectable		 5eewP-3txxA:
11.21
5eewQ-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.20A 5eewR-3txxA:
undetectable
5eewS-3txxA:
undetectable		 5eewR-3txxA:
11.21
5eewS-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 5eewS-3txxA:
undetectable
5eewT-3txxA:
undetectable		 5eewS-3txxA:
11.21
5eewT-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5eewU-3txxA:
undetectable
5eewV-3txxA:
undetectable		 5eewU-3txxA:
11.21
5eewV-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.18A 5eexC-3txxA:
undetectable
5eexD-3txxA:
undetectable		 5eexC-3txxA:
11.21
5eexD-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.20A 5eexG-3txxA:
undetectable
5eexH-3txxA:
undetectable		 5eexG-3txxA:
11.21
5eexH-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 11 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.19A 5eexI-3txxA:
undetectable
5eexJ-3txxA:
undetectable		 5eexI-3txxA:
11.21
5eexJ-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.19A 5eexA-3txxA:
undetectable
5eexK-3txxA:
undetectable		 5eexA-3txxA:
11.21
5eexK-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5eexN-3txxA:
undetectable
5eexO-3txxA:
undetectable		 5eexN-3txxA:
11.21
5eexO-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.21A 5eexP-3txxA:
undetectable
5eexQ-3txxA:
undetectable		 5eexP-3txxA:
11.21
5eexQ-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.19A 5eexR-3txxA:
undetectable
5eexS-3txxA:
undetectable		 5eexR-3txxA:
11.21
5eexS-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 5eexS-3txxA:
undetectable
5eexT-3txxA:
undetectable		 5eexS-3txxA:
11.21
5eexT-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5eexU-3txxA:
undetectable
5eexV-3txxA:
undetectable		 5eexU-3txxA:
11.21
5eexV-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.18A 5eeyC-3txxA:
undetectable
5eeyD-3txxA:
undetectable		 5eeyC-3txxA:
11.21
5eeyD-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.19A 5eeyG-3txxA:
undetectable
5eeyH-3txxA:
undetectable		 5eeyG-3txxA:
11.21
5eeyH-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 11 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.19A 5eeyI-3txxA:
undetectable
5eeyJ-3txxA:
undetectable		 5eeyI-3txxA:
11.21
5eeyJ-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5eeyN-3txxA:
undetectable
5eeyO-3txxA:
undetectable		 5eeyN-3txxA:
11.21
5eeyO-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.21A 5eeyP-3txxA:
undetectable
5eeyQ-3txxA:
undetectable		 5eeyP-3txxA:
11.21
5eeyQ-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.19A 5eeyR-3txxA:
undetectable
5eeyS-3txxA:
undetectable		 5eeyR-3txxA:
11.21
5eeyS-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 5eeyS-3txxA:
undetectable
5eeyT-3txxA:
undetectable		 5eeyS-3txxA:
11.21
5eeyT-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5eeyU-3txxA:
undetectable
5eeyV-3txxA:
undetectable		 5eeyU-3txxA:
11.21
5eeyV-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.18A 5eezC-3txxA:
undetectable
5eezD-3txxA:
undetectable		 5eezC-3txxA:
11.21
5eezD-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.19A 5eezG-3txxA:
undetectable
5eezH-3txxA:
undetectable		 5eezG-3txxA:
11.21
5eezH-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 11 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.18A 5eezI-3txxA:
undetectable
5eezJ-3txxA:
undetectable		 5eezI-3txxA:
11.21
5eezJ-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5eezN-3txxA:
undetectable
5eezO-3txxA:
undetectable		 5eezN-3txxA:
11.21
5eezO-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.21A 5eezP-3txxA:
undetectable
5eezQ-3txxA:
undetectable		 5eezP-3txxA:
11.21
5eezQ-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.19A 5eezR-3txxA:
undetectable
5eezS-3txxA:
undetectable		 5eezR-3txxA:
11.21
5eezS-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 5eezS-3txxA:
undetectable
5eezT-3txxA:
undetectable		 5eezS-3txxA:
11.21
5eezT-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5eezU-3txxA:
undetectable
5eezV-3txxA:
undetectable		 5eezU-3txxA:
11.21
5eezV-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.18A 5ef0C-3txxA:
undetectable
5ef0D-3txxA:
undetectable		 5ef0C-3txxA:
11.21
5ef0D-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.19A 5ef0G-3txxA:
undetectable
5ef0H-3txxA:
undetectable		 5ef0G-3txxA:
11.21
5ef0H-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 11 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.19A 5ef0I-3txxA:
undetectable
5ef0J-3txxA:
undetectable		 5ef0I-3txxA:
11.21
5ef0J-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.19A 5ef0A-3txxA:
undetectable
5ef0K-3txxA:
undetectable		 5ef0A-3txxA:
11.21
5ef0K-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5ef0N-3txxA:
undetectable
5ef0O-3txxA:
undetectable		 5ef0N-3txxA:
11.21
5ef0O-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.21A 5ef0P-3txxA:
undetectable
5ef0Q-3txxA:
undetectable		 5ef0P-3txxA:
11.21
5ef0Q-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.19A 5ef0R-3txxA:
undetectable
5ef0S-3txxA:
undetectable		 5ef0R-3txxA:
11.21
5ef0S-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 5ef0S-3txxA:
undetectable
5ef0T-3txxA:
undetectable		 5ef0S-3txxA:
11.21
5ef0T-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5ef0U-3txxA:
undetectable
5ef0V-3txxA:
undetectable		 5ef0U-3txxA:
11.21
5ef0V-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.18A 5ef1C-3txxA:
undetectable
5ef1D-3txxA:
undetectable		 5ef1C-3txxA:
11.21
5ef1D-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.19A 5ef1G-3txxA:
undetectable
5ef1H-3txxA:
undetectable		 5ef1G-3txxA:
11.21
5ef1H-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 11 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.18A 5ef1I-3txxA:
undetectable
5ef1J-3txxA:
undetectable		 5ef1I-3txxA:
11.21
5ef1J-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5ef1N-3txxA:
undetectable
5ef1O-3txxA:
undetectable		 5ef1N-3txxA:
11.21
5ef1O-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.21A 5ef1P-3txxA:
undetectable
5ef1Q-3txxA:
undetectable		 5ef1P-3txxA:
11.21
5ef1Q-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.19A 5ef1R-3txxA:
undetectable
5ef1S-3txxA:
undetectable		 5ef1R-3txxA:
11.21
5ef1S-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 5ef1S-3txxA:
undetectable
5ef1T-3txxA:
undetectable		 5ef1S-3txxA:
11.21
5ef1T-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5ef1U-3txxA:
undetectable
5ef1V-3txxA:
undetectable		 5ef1U-3txxA:
11.21
5ef1V-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.18A 5ef2C-3txxA:
undetectable
5ef2D-3txxA:
undetectable		 5ef2C-3txxA:
11.21
5ef2D-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.19A 5ef2G-3txxA:
undetectable
5ef2H-3txxA:
undetectable		 5ef2G-3txxA:
11.21
5ef2H-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 11 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.18A 5ef2I-3txxA:
undetectable
5ef2J-3txxA:
undetectable		 5ef2I-3txxA:
11.21
5ef2J-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5ef2N-3txxA:
undetectable
5ef2O-3txxA:
undetectable		 5ef2N-3txxA:
11.21
5ef2O-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.21A 5ef2P-3txxA:
undetectable
5ef2Q-3txxA:
undetectable		 5ef2P-3txxA:
11.21
5ef2Q-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.19A 5ef2R-3txxA:
undetectable
5ef2S-3txxA:
undetectable		 5ef2R-3txxA:
11.21
5ef2S-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.18A 5ef2S-3txxA:
undetectable
5ef2T-3txxA:
undetectable		 5ef2S-3txxA:
11.21
5ef2T-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5ef2U-3txxA:
undetectable
5ef2V-3txxA:
undetectable		 5ef2U-3txxA:
11.21
5ef2V-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.18A 5ef3C-3txxA:
undetectable
5ef3D-3txxA:
undetectable		 5ef3C-3txxA:
11.21
5ef3D-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.19A 5ef3G-3txxA:
undetectable
5ef3H-3txxA:
undetectable		 5ef3G-3txxA:
11.21
5ef3H-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 11 SER A  58
GLY A 124
HIS A 130
THR A 132
ILE A 122
 None
 1.18A 5ef3I-3txxA:
undetectable
5ef3J-3txxA:
undetectable		 5ef3I-3txxA:
11.21
5ef3J-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.19A 5ef3A-3txxA:
undetectable
5ef3K-3txxA:
undetectable		 5ef3A-3txxA:
11.21
5ef3K-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5ef3N-3txxA:
undetectable
5ef3O-3txxA:
undetectable		 5ef3N-3txxA:
11.21
5ef3O-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.21A 5ef3P-3txxA:
undetectable
5ef3Q-3txxA:
undetectable		 5ef3P-3txxA:
11.21
5ef3Q-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.19A 5ef3R-3txxA:
undetectable
5ef3S-3txxA:
undetectable		 5ef3R-3txxA:
11.21
5ef3S-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.17A 5ef3S-3txxA:
undetectable
5ef3T-3txxA:
undetectable		 5ef3S-3txxA:
11.21
5ef3T-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 10 GLY A 124
HIS A 130
THR A 132
ILE A 122
SER A  58
 None
 1.16A 5ef3U-3txxA:
undetectable
5ef3V-3txxA:
undetectable		 5ef3U-3txxA:
11.21
5ef3V-3txxA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 12 GLN A 133
ILE A 301
THR A 132
PHE A  59
SER A  52
 None
None
None
None
SO4  A 340 (-3.0A)
 1.38A 5l8oB-3txxA:
undetectable		 5l8oB-3txxA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 12 GLY A 285
SER A 288
LYS A 286
ASN A 253
GLN A 251
 None
 1.24A 5nwwA-3txxA:
undetectable		 5nwwA-3txxA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		4 / 7 SER A  52
HIS A 130
GLY A 124
ARG A 297
 SO4  A 340 (-3.0A)
None
None
None
 1.15A 6btxA-3txxA:
1.2		 6btxA-3txxA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 3txx PUTRESCINE
CARBAMOYLTRANSFERASE
(Enterococcus
faecalis) 		3 / 3 ASP A   4
SER A  90
SER A  94
 None
 0.66A 6mxtA-3txxA:
undetectable		 6mxtA-3txxA:
22.34