SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3txy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3txy ISOCHORISMATASE
FAMILY PROTEIN
FAMILY
(Burkholderia
thailandensis) 		5 / 11 PHE A  45
ILE A   3
ALA A 187
LEU A 189
ALA A  44
 None
 1.17A 1jb0B-3txyA:
undetectable		 1jb0B-3txyA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3txy ISOCHORISMATASE
FAMILY PROTEIN
FAMILY
(Burkholderia
thailandensis) 		4 / 7 THR A 139
VAL A 157
GLY A 129
THR A  38
 None
 0.92A 2a1mA-3txyA:
undetectable		 2a1mA-3txyA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 3txy ISOCHORISMATASE
FAMILY PROTEIN
FAMILY
(Burkholderia
thailandensis) 		5 / 12 ALA A 131
GLY A 135
THR A 159
GLY A 177
LEU A 176
 EDO  A 196 ( 3.9A)
None
None
None
None
 1.04A 2hw2A-3txyA:
undetectable		 2hw2A-3txyA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3txy ISOCHORISMATASE
FAMILY PROTEIN
FAMILY
(Burkholderia
thailandensis) 		4 / 7 ALA A  11
TYR A 148
ILE A  53
ILE A 125
 None
 1.14A 2zm7A-3txyA:
undetectable		 2zm7A-3txyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3txy ISOCHORISMATASE
FAMILY PROTEIN
FAMILY
(Burkholderia
thailandensis) 		5 / 11 PHE A  45
ILE A   3
ALA A 187
LEU A 189
ALA A  44
 None
 1.17A 3pcqB-3txyA:
undetectable		 3pcqB-3txyA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 3txy ISOCHORISMATASE
FAMILY PROTEIN
FAMILY
(Burkholderia
thailandensis) 		3 / 3 ASP A  97
LEU A  91
GLY A  92
 None
 0.56A 4xmfA-3txyA:
undetectable		 4xmfA-3txyA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 3txy ISOCHORISMATASE
FAMILY PROTEIN
FAMILY
(Burkholderia
thailandensis) 		4 / 6 PHE A  54
GLY A  92
ALA A  39
ARG A  46
 None
 1.24A 4yshB-3txyA:
undetectable		 4yshB-3txyA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3txy ISOCHORISMATASE
FAMILY PROTEIN
FAMILY
(Burkholderia
thailandensis) 		4 / 6 ALA A 131
THR A 132
VAL A 136
VAL A  34
 EDO  A 196 ( 3.9A)
None
None
None
 0.91A 5eclD-3txyA:
undetectable		 5eclD-3txyA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3txy ISOCHORISMATASE
FAMILY PROTEIN
FAMILY
(Burkholderia
thailandensis) 		5 / 12 VAL A 185
SER A 154
GLN A 178
ILE A 172
ALA A 168
 None
 1.09A 5n0sB-3txyA:
1.9		 5n0sB-3txyA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3txy ISOCHORISMATASE
FAMILY PROTEIN
FAMILY
(Burkholderia
thailandensis) 		4 / 6 GLY A 177
LEU A 176
VAL A 185
PHE A  45
 None
 0.97A 6h7lA-3txyA:
undetectable		 6h7lA-3txyA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3txy ISOCHORISMATASE
FAMILY PROTEIN
FAMILY
(Burkholderia
thailandensis) 		4 / 6 GLY A 177
LEU A 176
VAL A 185
PHE A  45
 None
 0.97A 6h7lB-3txyA:
undetectable		 6h7lB-3txyA:
20.51