SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ty1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 5 SER A 338
THR A 337
GLU A 346
GLY A 141
 None
 1.10A 1icrA-3ty1A:
undetectable
1icrB-3ty1A:
undetectable		 1icrA-3ty1A:
18.49
1icrB-3ty1A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 5 GLU A 346
GLY A 141
SER A 338
THR A 337
 None
 1.12A 1icrA-3ty1A:
undetectable
1icrB-3ty1A:
undetectable		 1icrA-3ty1A:
18.49
1icrB-3ty1A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 6 SER A 338
THR A 337
GLU A 346
GLY A 141
 None
 1.11A 1icuA-3ty1A:
undetectable
1icuB-3ty1A:
undetectable		 1icuA-3ty1A:
18.49
1icuB-3ty1A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 6 GLU A 346
GLY A 141
SER A 338
THR A 337
 None
 1.11A 1icuA-3ty1A:
undetectable
1icuB-3ty1A:
undetectable		 1icuA-3ty1A:
18.49
1icuB-3ty1A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 6 SER A 338
THR A 337
GLU A 346
GLY A 141
 None
 1.09A 1icuC-3ty1A:
undetectable
1icuD-3ty1A:
undetectable		 1icuC-3ty1A:
18.49
1icuD-3ty1A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 5 SER A 338
THR A 337
GLU A 346
GLY A 141
 None
 1.12A 1icvC-3ty1A:
undetectable
1icvD-3ty1A:
undetectable		 1icvC-3ty1A:
18.49
1icvD-3ty1A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 5 GLU A 346
GLY A 141
SER A 338
THR A 337
 None
 1.12A 1icvC-3ty1A:
undetectable
1icvD-3ty1A:
undetectable		 1icvC-3ty1A:
18.49
1icvD-3ty1A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 6 SER A 338
THR A 337
GLU A 346
GLY A 141
 None
 1.11A 1kqbA-3ty1A:
undetectable
1kqbB-3ty1A:
undetectable		 1kqbA-3ty1A:
19.18
1kqbB-3ty1A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 5 GLU A 346
GLY A 141
SER A 338
THR A 337
 None
 1.11A 1kqbA-3ty1A:
undetectable
1kqbB-3ty1A:
undetectable		 1kqbA-3ty1A:
19.18
1kqbB-3ty1A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 6 SER A 338
THR A 337
GLU A 346
GLY A 141
 None
 1.13A 1kqbC-3ty1A:
undetectable
1kqbD-3ty1A:
undetectable		 1kqbC-3ty1A:
19.18
1kqbD-3ty1A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 6 GLU A 346
GLY A 141
SER A 338
THR A 337
 None
 1.12A 1kqbC-3ty1A:
undetectable
1kqbD-3ty1A:
undetectable		 1kqbC-3ty1A:
19.18
1kqbD-3ty1A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 8 LEU A 210
THR A 195
LEU A 199
VAL A 183
 None
 0.82A 1sn5C-3ty1A:
undetectable		 1sn5C-3ty1A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 7 LEU A 210
THR A 195
LEU A 199
VAL A 183
 None
 0.84A 1tyrB-3ty1A:
undetectable		 1tyrB-3ty1A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 8 ASP A 255
LYS A 258
GLY A 260
THR A 322
 CL  A 504 ( 4.3A)
None
None
None
 1.00A 2aouA-3ty1A:
undetectable		 2aouA-3ty1A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 6 ALA A  20
ASP A 171
GLU A 168
ARG A 180
 None
 1.34A 2ouzA-3ty1A:
undetectable		 2ouzA-3ty1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 7 SER A 360
LYS A 184
LEU A 196
THR A 215
 None
 0.54A 3cfqA-3ty1A:
undetectable
3cfqB-3ty1A:
undetectable		 3cfqA-3ty1A:
16.15
3cfqB-3ty1A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		3 / 3 ILE A 114
VAL A 109
ARG A  85
 None
 0.58A 3p73A-3ty1A:
undetectable		 3p73A-3ty1A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 8 LEU A 210
THR A 195
LEU A 199
VAL A 183
 None
 0.83A 4ik6B-3ty1A:
undetectable		 4ik6B-3ty1A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 8 LEU A 210
THR A 195
LEU A 199
VAL A 183
 None
 0.76A 4ik7B-3ty1A:
undetectable		 4ik7B-3ty1A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 7 LYS A 184
LEU A 182
LEU A 196
SER A 360
 None
 0.81A 4ikjA-3ty1A:
undetectable
4ikjB-3ty1A:
undetectable		 4ikjA-3ty1A:
17.45
4ikjB-3ty1A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 7 LYS A 184
LEU A 196
THR A 215
SER A 360
 None
 0.44A 4ikjA-3ty1A:
undetectable
4ikjB-3ty1A:
undetectable		 4ikjA-3ty1A:
17.45
4ikjB-3ty1A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 7 SER A 360
LYS A 184
LEU A 182
LEU A 196
 None
 1.01A 4ikkA-3ty1A:
undetectable
4ikkB-3ty1A:
undetectable		 4ikkA-3ty1A:
17.45
4ikkB-3ty1A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 7 SER A 360
LYS A 184
LEU A 196
THR A 215
 None
 0.78A 4ikkA-3ty1A:
undetectable
4ikkB-3ty1A:
undetectable		 4ikkA-3ty1A:
17.45
4ikkB-3ty1A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 7 LYS A 184
LEU A 196
THR A 215
SER A 360
 None
 0.45A 4iklA-3ty1A:
undetectable
4iklB-3ty1A:
undetectable		 4iklA-3ty1A:
17.45
4iklB-3ty1A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 8 SER A 360
LYS A 184
LEU A 196
THR A 215
 None
 0.76A 4iklA-3ty1A:
undetectable
4iklB-3ty1A:
undetectable		 4iklA-3ty1A:
17.45
4iklB-3ty1A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A 306
TYR A 137
LEU A 355
LEU A 193
LEU A 313
 None
 1.12A 4j03A-3ty1A:
undetectable		 4j03A-3ty1A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 8 LEU A 316
PHE A 243
TRP A 264
GLN A 387
 None
 1.21A 4j7uD-3ty1A:
undetectable		 4j7uD-3ty1A:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 7 PHE A 363
ASP A 364
GLN A 312
PRO A 314
 None
None
SO4  A 511 (-3.9A)
None
 1.07A 4pcuA-3ty1A:
undetectable		 4pcuA-3ty1A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		5 / 12 LEU A 210
ASP A 212
THR A 195
LEU A 313
GLY A 336
 None
 1.38A 5utuF-3ty1A:
undetectable		 5utuF-3ty1A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 5 GLN A 290
THR A 291
THR A 337
LEU A 365
 None
 1.32A 6aphA-3ty1A:
undetectable		 6aphA-3ty1A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 8 HIS A 229
ASN A 129
TRP A 101
GLU A 130
 SO4  A 513 (-3.9A)
None
None
None
 1.12A 6b94A-3ty1A:
undetectable		 6b94A-3ty1A:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_2
(-)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 4 GLN A 290
THR A 291
THR A 337
LEU A 365
 None
 1.33A 6f3mA-3ty1A:
undetectable		 6f3mA-3ty1A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_2
(-)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 4 GLN A 290
THR A 291
THR A 337
LEU A 365
 None
 1.32A 6f3mC-3ty1A:
undetectable		 6f3mC-3ty1A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE
(Klebsiella
pneumoniae) 		4 / 5 GLN A 290
THR A 291
THR A 337
LEU A 365
 None
 1.36A 6gbnB-3ty1A:
undetectable		 6gbnB-3ty1A:
21.98