SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ty9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		3 / 3 HIS A 532
MET A 609
MET A 738
 AMP  A 900 (-4.6A)
None
None
 0.83A 2vj1A-3ty9A:
undetectable		 2vj1A-3ty9A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		5 / 12 MET A 574
ILE A 581
VAL A 541
ILE A 540
ILE A 561
 None
 1.11A 2yzqA-3ty9A:
undetectable		 2yzqA-3ty9A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		5 / 9 VAL A 602
VAL A 843
GLY A 711
ILE A 706
LEU A 707
 None
 0.95A 2z0yB-3ty9A:
undetectable		 2z0yB-3ty9A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWU_A_ADNA501_1
(DNA LIGASE)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		6 / 12 GLU A 529
ARG A 565
GLU A 607
VAL A 772
LYS A 774
LYS A 792
 AMP  A 900 (-4.0A)
None
AMP  A 900 (-3.0A)
AMP  A 900 ( 4.8A)
AMP  A 900 (-3.2A)
AMP  A 900 (-2.8A)
 0.82A 3qwuA-3ty9A:
10.6		 3qwuA-3ty9A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWU_A_ADNA501_1
(DNA LIGASE)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		6 / 12 GLU A 529
GLU A 607
PHE A 704
VAL A 772
LYS A 774
LYS A 792
 AMP  A 900 (-4.0A)
AMP  A 900 (-3.0A)
AMP  A 900 (-3.3A)
AMP  A 900 ( 4.8A)
AMP  A 900 (-3.2A)
AMP  A 900 (-2.8A)
 0.54A 3qwuA-3ty9A:
10.6		 3qwuA-3ty9A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWU_A_ADNA501_1
(DNA LIGASE)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		6 / 12 GLU A 529
LYS A 531
ARG A 565
GLU A 607
VAL A 772
LYS A 774
 AMP  A 900 (-4.0A)
AMP  A 900 (-1.5A)
None
AMP  A 900 (-3.0A)
AMP  A 900 ( 4.8A)
AMP  A 900 (-3.2A)
 0.95A 3qwuA-3ty9A:
10.6		 3qwuA-3ty9A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWU_A_ADNA501_1
(DNA LIGASE)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		6 / 12 GLU A 529
LYS A 531
GLU A 607
PHE A 704
VAL A 772
LYS A 774
 AMP  A 900 (-4.0A)
AMP  A 900 (-1.5A)
AMP  A 900 (-3.0A)
AMP  A 900 (-3.3A)
AMP  A 900 ( 4.8A)
AMP  A 900 (-3.2A)
 0.71A 3qwuA-3ty9A:
10.6		 3qwuA-3ty9A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWU_B_ADNB501_1
(DNA LIGASE)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		6 / 11 GLU A 529
LYS A 531
ARG A 565
GLU A 607
VAL A 772
LYS A 774
 AMP  A 900 (-4.0A)
AMP  A 900 (-1.5A)
None
AMP  A 900 (-3.0A)
AMP  A 900 ( 4.8A)
AMP  A 900 (-3.2A)
 0.87A 3qwuB-3ty9A:
10.9		 3qwuB-3ty9A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWU_B_ADNB501_1
(DNA LIGASE)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		6 / 11 GLU A 529
LYS A 531
GLU A 607
PHE A 704
VAL A 772
LYS A 774
 AMP  A 900 (-4.0A)
AMP  A 900 (-1.5A)
AMP  A 900 (-3.0A)
AMP  A 900 (-3.3A)
AMP  A 900 ( 4.8A)
AMP  A 900 (-3.2A)
 0.49A 3qwuB-3ty9A:
10.9		 3qwuB-3ty9A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		4 / 7 GLU A 513
GLU A 516
TYR A 517
ARG A 521
 None
 1.03A 4fgzA-3ty9A:
undetectable		 4fgzA-3ty9A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		3 / 3 TYR A 491
PHE A 704
ARG A 536
 None
AMP  A 900 (-3.3A)
AMP  A 900 (-4.3A)
 1.22A 4g19D-3ty9A:
undetectable		 4g19D-3ty9A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		4 / 5 TYR A 807
ARG A 796
GLU A 509
VAL A 773
 None
 1.10A 4nkvB-3ty9A:
undetectable		 4nkvB-3ty9A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		4 / 7 GLU A 577
ASP A 485
ALA A 484
TYR A 563
 None
 1.20A 4zz8A-3ty9A:
undetectable		 4zz8A-3ty9A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		3 / 3 GLU A 513
TYR A 517
ARG A 521
 None
 0.79A 5uunB-3ty9A:
undetectable		 5uunB-3ty9A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3ty9 POLYNUCLEOTIDE
2',3'-CYCLIC
PHOSPHATE
PHOSPHODIESTERASE /
POLYNUCLEOTIDE
5'-HYDROXYL-KINASE /
POLYNUCLEOTIDE
3'-PHOSPHATASE
(Ruminiclostridiu
m
thermocellum) 		3 / 3 ASN A 718
VAL A 713
HIS A 714
 None
 0.85A 6a5yD-3ty9A:
undetectable		 6a5yD-3ty9A:
13.58