SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tyg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSF_B_PZIB802_0 (GLUTAMATE RECEPTOR 2)	3tyg	ENVELOPE GLYCOPROTEIN GP160 (Human immunodeficiency virus 1)	3 / 3	SER A 154 ASP A 27 ASN A 83	None	1.00A	3lsfB-3tygA: undetectable 3lsfE-3tygA: undetectable	3lsfB-3tygA: 20.08 3lsfE-3tygA: 20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSF_E_PZIE802_0 (GLUTAMATE RECEPTOR 2)	3tyg	ENVELOPE GLYCOPROTEIN GP160 (Human immunodeficiency virus 1)	3 / 3	ASP A 27 ASN A 83 SER A 154	None	0.93A	3lsfB-3tygA: undetectable 3lsfE-3tygA: undetectable	3lsfB-3tygA: 20.08 3lsfE-3tygA: 20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K39_A_SAMA504_0 (ANAEROBIC SULFATASE-MATURATING ENZYME)	3tyg	ENVELOPE GLYCOPROTEIN GP160 (Human immunodeficiency virus 1)	5 / 12	PHE A 180 ASN A 121 VAL A 95 ILE A 19 LEU A 22	None NAG A 200 (-1.9A) None None None	1.32A	4k39A-3tygA: undetectable	4k39A-3tygA: 17.16