SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tyj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_B_CAMB502_0
(CYTOCHROME P450-CAM)		 3tyj BCLA PROTEIN
(Bacillus
anthracis) 		5 / 9 THR A 142
LEU A 198
VAL A 193
GLY A 150
VAL A 138
 None
 1.48A 1dz8B-3tyjA:
undetectable		 1dz8B-3tyjA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 3tyj BCLA PROTEIN
(Bacillus
anthracis) 		5 / 11 LEU A 167
ILE A 174
VAL A 105
LEU A 200
SER A 146
 None
 1.21A 2bxeA-3tyjA:
undetectable		 2bxeA-3tyjA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 3tyj BCLA PROTEIN
(Bacillus
anthracis) 		5 / 12 LEU A 167
ILE A 174
VAL A 105
LEU A 200
SER A 146
 None
 1.21A 2bxeB-3tyjA:
undetectable		 2bxeB-3tyjA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3tyj BCLA PROTEIN
(Bacillus
anthracis) 		5 / 11 ALA A 140
ILE A 139
PHE A 126
LEU A  87
ILE A 136
 None
 1.12A 2h42A-3tyjA:
undetectable		 2h42A-3tyjA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 3tyj BCLA PROTEIN
(Bacillus
anthracis) 		5 / 12 ILE A 208
ILE A 118
SER A 119
PRO A  84
ILE A 209
 None
 1.07A 3cd2A-3tyjA:
undetectable		 3cd2A-3tyjA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 3tyj BCLA PROTEIN
(Bacillus
anthracis) 		5 / 12 LEU A  97
LEU A 151
GLY A 149
SER A 146
SER A 205
 None
 1.48A 4zbrA-3tyjA:
undetectable		 4zbrA-3tyjA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 3tyj BCLA PROTEIN
(Bacillus
anthracis) 		4 / 5 ASN A 108
VAL A 193
LEU A 198
SER A 205
 None
 1.19A 6a7pA-3tyjA:
undetectable		 6a7pA-3tyjA:
12.65