SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tyt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 3tyt HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN L
(Mus
musculus) 		3 / 3 GLU A 511
LYS A 530
VAL A 529
 None
 0.98A 1l2iA-3tytA:
undetectable		 1l2iA-3tytA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 3tyt HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN L
(Mus
musculus) 		5 / 12 LEU A 553
LEU A 556
MET A 391
VAL A 396
LEU A 386
 None
 1.06A 2q7kA-3tytA:
undetectable		 2q7kA-3tytA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3tyt HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN L
(Mus
musculus) 		5 / 12 LEU A 575
PRO A 526
VAL A 529
VAL A 523
GLU A 520
 None
None
None
EDO  A 641 ( 4.8A)
None
 1.18A 3w1wB-3tytA:
undetectable		 3w1wB-3tytA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 3tyt HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN L
(Mus
musculus) 		3 / 3 CYH A 578
ASN A 491
LYS A 576
 None
 1.06A 4k50A-3tytA:
undetectable		 4k50A-3tytA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_NPSA602_1
(SERUM ALBUMIN)		 3tyt HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN L
(Mus
musculus) 		5 / 12 LEU A 575
ASN A 560
LEU A 402
ARG A 481
LEU A 500
 None
 1.42A 5dbyA-3tytA:
undetectable		 5dbyA-3tytA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3tyt HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN L
(Mus
musculus) 		3 / 3 LEU A 402
PHE A 482
ILE A 493
 None
 0.77A 5dzk1-3tytA:
undetectable
5dzkF-3tytA:
undetectable
5dzkM-3tytA:
undetectable		 5dzk1-3tytA:
1.18
5dzkF-3tytA:
20.80
5dzkM-3tytA:
21.82