SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)
3tz1 TROPONIN C
(Chlamys
nipponensis)
3 / 3 MET A 147
VAL A 138
GLU A 129
None
0.83A 3c6gA-3tz1A:
undetectable
3c6gA-3tz1A:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)
3tz1 TROPONIN C
TROPONIN I

(Chlamys
nipponensis;
Chlamys
nipponensis)
5 / 12 MET B 157
ILE B 156
VAL A  93
LEU A 107
PHE A 143
None
1.30A 5bykA-3tz1B:
undetectable
5bykA-3tz1B:
13.33