SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u02'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		6 / 11 ASP A   8
GLY A  56
ALA A  57
GLY A  22
ILE A  21
VAL A  96
 None
TPO  A  18 ( 4.6A)
None
TPO  A  18 ( 3.7A)
TPO  A  18 ( 4.2A)
None
 1.40A 1hxwB-3u02A:
undetectable		 1hxwB-3u02A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		6 / 12 ILE A  21
VAL A  80
ALA A  33
SER A  30
GLY A   6
LEU A   2
 TPO  A  18 ( 4.2A)
None
None
None
None
None
 1.39A 1nbhB-3u02A:
undetectable		 1nbhB-3u02A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 12 GLY A 146
ALA A 149
ALA A 123
ASP A   8
ILE A 144
 None
 1.16A 1nt2A-3u02A:
undetectable		 1nt2A-3u02A:
25.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		4 / 8 LEU A  83
GLU A  82
ILE A  24
TYR A  20
 None
 1.12A 1qvtA-3u02A:
undetectable		 1qvtA-3u02A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		6 / 10 ASP A   8
GLY A  56
ALA A  57
GLY A  22
ILE A  21
VAL A  96
 None
TPO  A  18 ( 4.6A)
None
TPO  A  18 ( 3.7A)
TPO  A  18 ( 4.2A)
None
 1.44A 1t3rA-3u02A:
undetectable		 1t3rA-3u02A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 12 ALA A 123
GLY A   6
GLY A 146
ILE A 143
ILE A   5
 None
 1.11A 1x1aA-3u02A:
undetectable		 1x1aA-3u02A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_B_STIB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		4 / 6 LEU A 111
VAL A 134
VAL A 126
ILE A 150
 None
 1.10A 2hyyB-3u02A:
undetectable		 2hyyB-3u02A:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		4 / 8 LEU A  44
LEU A 106
VAL A  96
GLY A   6
 None
 0.87A 2po5A-3u02A:
undetectable		 2po5A-3u02A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		4 / 8 LEU A  44
LEU A 106
VAL A  96
GLY A   6
 None
 0.73A 2po5B-3u02A:
undetectable		 2po5B-3u02A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_1
(PROTEASE RETROPEPSIN)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 11 ASP A   9
ASP A   8
GLY A  22
ILE A  24
ILE A  95
 TPO  A  18 ( 4.7A)
None
TPO  A  18 ( 3.7A)
None
None
 1.03A 2qhcA-3u02A:
undetectable		 2qhcA-3u02A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 11 GLY A 142
ASP A   8
ALA A  57
ALA A  59
ALA A 123
 None
 0.98A 3g88A-3u02A:
undetectable		 3g88A-3u02A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 11 GLY A 146
GLY A 142
ASP A   8
ALA A  59
ALA A 123
 None
 1.09A 3g88A-3u02A:
undetectable		 3g88A-3u02A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 11 GLY A 142
ASP A   8
ALA A  57
ALA A  59
ALA A 123
 None
 1.00A 3g88B-3u02A:
undetectable		 3g88B-3u02A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 11 GLY A 146
GLY A 142
ASP A   8
ALA A  59
ALA A 123
 None
 1.11A 3g88B-3u02A:
undetectable		 3g88B-3u02A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 12 GLY A 146
GLY A 142
ASP A   8
ALA A  59
ALA A 123
 None
 1.09A 3g89A-3u02A:
undetectable		 3g89A-3u02A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 11 GLY A 146
GLY A 142
ASP A   8
ALA A  59
ALA A 123
 None
 1.10A 3g89B-3u02A:
undetectable		 3g89B-3u02A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 12 GLY A 146
GLY A 142
ASP A   8
ALA A  59
ALA A 123
 None
 1.04A 3g8bA-3u02A:
undetectable		 3g8bA-3u02A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 12 GLY A 146
ALA A 149
ALA A 123
ASP A   8
ILE A 144
 None
 1.08A 3id6C-3u02A:
undetectable		 3id6C-3u02A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_A_STIA2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		4 / 6 LEU A 111
VAL A 134
VAL A 126
ILE A 150
 None
 1.07A 3k5vA-3u02A:
undetectable		 3k5vA-3u02A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_B_STIB2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		4 / 6 LEU A 111
VAL A 134
VAL A 126
ILE A 150
 None
 1.01A 3k5vB-3u02A:
undetectable		 3k5vB-3u02A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		6 / 10 ASP A   8
GLY A  56
ALA A  57
GLY A  22
ILE A  21
VAL A  96
 None
TPO  A  18 ( 4.6A)
None
TPO  A  18 ( 3.7A)
TPO  A  18 ( 4.2A)
None
 1.35A 3lzvA-3u02A:
undetectable		 3lzvA-3u02A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 12 GLY A  56
ALA A  57
GLY A  22
ILE A  21
VAL A  96
 TPO  A  18 ( 4.6A)
None
TPO  A  18 ( 3.7A)
TPO  A  18 ( 4.2A)
None
 1.15A 3n3iA-3u02A:
undetectable		 3n3iA-3u02A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		6 / 12 ASP A   8
GLY A  56
ALA A  57
GLY A  22
ILE A  21
VAL A  96
 None
TPO  A  18 ( 4.6A)
None
TPO  A  18 ( 3.7A)
TPO  A  18 ( 4.2A)
None
 1.43A 3ndtB-3u02A:
undetectable		 3ndtB-3u02A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 10 GLY A  56
ALA A  57
GLY A  22
ILE A  21
VAL A  96
 TPO  A  18 ( 4.6A)
None
TPO  A  18 ( 3.7A)
TPO  A  18 ( 4.2A)
None
 1.11A 3nu9B-3u02A:
undetectable		 3nu9B-3u02A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		6 / 10 ASP A   8
GLY A  56
ALA A  57
GLY A  22
ILE A  21
VAL A  96
 None
TPO  A  18 ( 4.6A)
None
TPO  A  18 ( 3.7A)
TPO  A  18 ( 4.2A)
None
 1.34A 3oy4B-3u02A:
undetectable		 3oy4B-3u02A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 11 ASP A   8
GLY A  22
ILE A  24
ILE A  77
ILE A  95
 None
TPO  A  18 ( 3.7A)
None
None
None
 1.18A 3s53B-3u02A:
undetectable		 3s53B-3u02A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		6 / 9 ARG A  81
ASP A   8
GLY A  22
ILE A  24
ILE A  77
ILE A  95
 None
None
TPO  A  18 ( 3.7A)
None
None
None
 1.50A 3s56B-3u02A:
undetectable		 3s56B-3u02A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 12 TYR A  79
PHE A  97
ILE A   3
VAL A  72
ILE A  69
 None
 0.91A 4aztA-3u02A:
undetectable		 4aztA-3u02A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		6 / 10 ASP A   8
GLY A  56
ALA A  57
GLY A  22
ILE A  21
VAL A  96
 None
TPO  A  18 ( 4.6A)
None
TPO  A  18 ( 3.7A)
TPO  A  18 ( 4.2A)
None
 1.37A 4dqfB-3u02A:
undetectable		 4dqfB-3u02A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		6 / 11 ASP A   8
GLY A  56
ALA A  57
GLY A  22
ILE A  21
VAL A  96
 None
TPO  A  18 ( 4.6A)
None
TPO  A  18 ( 3.7A)
TPO  A  18 ( 4.2A)
None
 1.34A 4q1xA-3u02A:
undetectable		 4q1xA-3u02A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		6 / 10 ASP A   8
GLY A  56
ALA A  57
GLY A  22
ILE A  21
VAL A  96
 None
TPO  A  18 ( 4.6A)
None
TPO  A  18 ( 3.7A)
TPO  A  18 ( 4.2A)
None
 1.33A 4q1yA-3u02A:
undetectable		 4q1yA-3u02A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		5 / 12 TYR A  79
PHE A  97
ILE A   3
VAL A  72
ILE A  69
 None
 1.00A 4uw0A-3u02A:
undetectable		 4uw0A-3u02A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		4 / 4 LEU A   2
ILE A  64
GLY A 100
ILE A  69
 None
 0.84A 5dzk3-3u02A:
undetectable
5dzkm-3u02A:
undetectable		 5dzk3-3u02A:
1.44
5dzkm-3u02A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		4 / 5 ILE A  64
GLY A 100
ILE A  69
LEU A   2
 None
 0.76A 5dzkB-3u02A:
undetectable
5dzkI-3u02A:
undetectable
5dzkW-3u02A:
undetectable		 5dzkB-3u02A:
21.84
5dzkI-3u02A:
21.69
5dzkW-3u02A:
1.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		4 / 5 ILE A  64
GLY A 100
ILE A  69
LEU A   2
 None
 0.74A 5dzki-3u02A:
undetectable
5dzkj-3u02A:
undetectable
5dzkx-3u02A:
undetectable		 5dzki-3u02A:
21.69
5dzkj-3u02A:
21.69
5dzkx-3u02A:
1.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		4 / 5 ILE A  64
GLY A 100
ILE A  69
LEU A   2
 None
 0.78A 5dzkd-3u02A:
undetectable
5dzkk-3u02A:
undetectable
5dzky-3u02A:
undetectable		 5dzkd-3u02A:
21.84
5dzkk-3u02A:
21.69
5dzky-3u02A:
1.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		4 / 4 ILE A  64
GLY A 100
ILE A  69
LEU A   2
 None
 0.74A 5dzkl-3u02A:
undetectable
5dzkz-3u02A:
undetectable		 5dzkl-3u02A:
21.69
5dzkz-3u02A:
1.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		6 / 12 ARG A  81
ASP A   8
GLY A  22
ILE A  24
ILE A  77
ILE A  95
 None
None
TPO  A  18 ( 3.7A)
None
None
None
 1.32A 5e5jB-3u02A:
undetectable		 5e5jB-3u02A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		3 / 3 ILE A  69
ILE A  32
MET A   1
 None
 0.71A 5i9yA-3u02A:
undetectable		 5i9yA-3u02A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		4 / 6 ILE A  24
GLY A   6
MET A  60
ILE A  21
 None
None
None
TPO  A  18 ( 4.2A)
 0.94A 5j4nB-3u02A:
undetectable		 5j4nB-3u02A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 3u02 PUTATIVE
TRANSCRIPTION-ASSOCI
ATED PROTEIN TFIIS
(Pyrococcus
furiosus) 		4 / 8 ILE A   3
ALA A  33
LEU A  75
ILE A  69
 None
 0.84A 5uihA-3u02A:
undetectable		 5uihA-3u02A:
15.48