SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u04'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 3u04 PEPTIDE DEFORMYLASE
1
(Ehrlichia
chaffeensis) 		4 / 8 LEU A  45
HIS A 153
GLU A 154
HIS A 157
 BB2  A 210 (-4.1A)
ZN  A 200 ( 3.3A)
BB2  A 210 (-2.7A)
ZN  A 200 ( 3.3A)
 0.23A 2jihB-3u04A:
undetectable		 2jihB-3u04A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 3u04 PEPTIDE DEFORMYLASE
1
(Ehrlichia
chaffeensis) 		3 / 3 LYS A  56
LYS A  23
VAL A  21
 None
 0.81A 3brfA-3u04A:
undetectable		 3brfA-3u04A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 3u04 PEPTIDE DEFORMYLASE
1
(Ehrlichia
chaffeensis) 		5 / 12 MET A  35
LEU A  47
GLY A  46
LEU A 158
ILE A  92
 None
None
BB2  A 210 (-4.6A)
None
None
 1.28A 3h52A-3u04A:
undetectable		 3h52A-3u04A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 3u04 PEPTIDE DEFORMYLASE
1
(Ehrlichia
chaffeensis) 		3 / 3 HIS A 153
GLU A 154
HIS A 157
 ZN  A 200 ( 3.3A)
BB2  A 210 (-2.7A)
ZN  A 200 ( 3.3A)
 0.22A 3kecB-3u04A:
undetectable		 3kecB-3u04A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3u04 PEPTIDE DEFORMYLASE
1
(Ehrlichia
chaffeensis) 		4 / 7 LEU A  14
THR A   8
ILE A   6
GLY A  53
 None
 0.94A 4eqlA-3u04A:
undetectable		 4eqlA-3u04A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3u04 PEPTIDE DEFORMYLASE
1
(Ehrlichia
chaffeensis) 		4 / 7 LEU A  14
THR A   8
ILE A   6
GLY A  53
 None
 0.87A 4l39B-3u04A:
undetectable		 4l39B-3u04A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3u04 PEPTIDE DEFORMYLASE
1
(Ehrlichia
chaffeensis) 		4 / 5 MET A  39
TYR A  90
GLY A  88
GLY A  87
 None
 0.92A 5x7pA-3u04A:
undetectable		 5x7pA-3u04A:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3u04 PEPTIDE DEFORMYLASE
1
(Ehrlichia
chaffeensis) 		4 / 6 MET A  39
TYR A  90
GLY A  88
GLY A  87
 None
 0.95A 5x7pB-3u04A:
undetectable		 5x7pB-3u04A:
9.27