SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u0f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 11 ALA A 204
ASP A 304
GLY A 303
TYR A 220
ALA A 326
 None
 1.08A 1b02A-3u0fA:
undetectable		 1b02A-3u0fA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.27A 1c9sA-3u0fA:
undetectable
1c9sK-3u0fA:
undetectable		 1c9sA-3u0fA:
10.22
1c9sK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.24A 1c9sB-3u0fA:
undetectable
1c9sC-3u0fA:
undetectable		 1c9sB-3u0fA:
10.22
1c9sC-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.27A 1c9sC-3u0fA:
undetectable
1c9sD-3u0fA:
undetectable		 1c9sC-3u0fA:
10.22
1c9sD-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 1c9sD-3u0fA:
undetectable
1c9sE-3u0fA:
undetectable		 1c9sD-3u0fA:
10.22
1c9sE-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.24A 1c9sE-3u0fA:
undetectable
1c9sF-3u0fA:
undetectable		 1c9sE-3u0fA:
10.22
1c9sF-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.24A 1c9sF-3u0fA:
undetectable
1c9sG-3u0fA:
undetectable		 1c9sF-3u0fA:
10.22
1c9sG-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 1c9sG-3u0fA:
undetectable
1c9sH-3u0fA:
undetectable		 1c9sG-3u0fA:
10.22
1c9sH-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.25A 1c9sH-3u0fA:
undetectable
1c9sI-3u0fA:
undetectable		 1c9sH-3u0fA:
10.22
1c9sI-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.25A 1c9sJ-3u0fA:
undetectable
1c9sK-3u0fA:
undetectable		 1c9sJ-3u0fA:
10.22
1c9sK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 SER A 164
VAL A 340
GLY A 339
GLY A 234
SER A  14
 None
 1.06A 1fduC-3u0fA:
undetectable		 1fduC-3u0fA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.26A 1gtfA-3u0fA:
undetectable
1gtfK-3u0fA:
undetectable		 1gtfA-3u0fA:
10.22
1gtfK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.27A 1gtfB-3u0fA:
undetectable
1gtfC-3u0fA:
undetectable		 1gtfB-3u0fA:
10.22
1gtfC-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 1gtfC-3u0fA:
undetectable
1gtfD-3u0fA:
undetectable		 1gtfC-3u0fA:
10.22
1gtfD-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.24A 1gtfE-3u0fA:
undetectable
1gtfF-3u0fA:
undetectable		 1gtfE-3u0fA:
10.22
1gtfF-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.24A 1gtfG-3u0fA:
undetectable
1gtfH-3u0fA:
undetectable		 1gtfG-3u0fA:
10.22
1gtfH-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 1gtfH-3u0fA:
undetectable
1gtfI-3u0fA:
undetectable		 1gtfH-3u0fA:
10.22
1gtfI-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 1gtfI-3u0fA:
undetectable
1gtfJ-3u0fA:
undetectable		 1gtfI-3u0fA:
10.22
1gtfJ-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.32A 1gtfL-3u0fA:
undetectable
1gtfV-3u0fA:
undetectable		 1gtfL-3u0fA:
10.22
1gtfV-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 GLY A 332
HIS A 333
ALA A 219
THR A 327
ALA A 297
 None
 1.42A 1gtnO-3u0fA:
undetectable
1gtnP-3u0fA:
undetectable		 1gtnO-3u0fA:
10.22
1gtnP-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLY A 332
HIS A 333
ALA A 219
THR A 327
ALA A 297
 None
 1.41A 1gtnQ-3u0fA:
undetectable
1gtnR-3u0fA:
undetectable		 1gtnQ-3u0fA:
10.22
1gtnR-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		4 / 6 ASN A 165
ILE A 344
SER A 346
ASN A 294
 None
None
None
NA  A 410 (-3.4A)
 0.98A 1h7xA-3u0fA:
undetectable		 1h7xA-3u0fA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		4 / 6 ASN A 165
ILE A 344
SER A 346
ASN A 294
 None
None
None
NA  A 410 (-3.4A)
 0.97A 1h7xB-3u0fA:
undetectable		 1h7xB-3u0fA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		4 / 6 ASN A 165
ILE A 344
SER A 346
ASN A 294
 None
None
None
NA  A 410 (-3.4A)
 0.99A 1h7xC-3u0fA:
undetectable		 1h7xC-3u0fA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		4 / 6 ASN A 165
ILE A 344
SER A 346
ASN A 294
 None
None
None
NA  A 410 (-3.4A)
 0.98A 1h7xD-3u0fA:
undetectable		 1h7xD-3u0fA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 11 GLY A 106
PRO A 107
GLU A 189
GLY A 231
ILE A  11
 07L  A 411 (-3.5A)
None
07L  A 411 ( 4.0A)
None
None
 1.03A 1jzsA-3u0fA:
undetectable		 1jzsA-3u0fA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		4 / 7 SER A 104
PRO A 107
SER A 138
ALA A 140
 None
 1.02A 1k5qA-3u0fA:
undetectable
1k5qB-3u0fA:
undetectable		 1k5qA-3u0fA:
20.72
1k5qB-3u0fA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 GLY A 303
ALA A 219
SER A 299
GLY A 392
HIS A 333
 None
 1.30A 1nbiC-3u0fA:
undetectable		 1nbiC-3u0fA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 GLY A 303
ALA A 219
SER A 299
GLY A 392
HIS A 333
 None
 1.30A 1nbiD-3u0fA:
undetectable		 1nbiD-3u0fA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.23A 1utdA-3u0fA:
undetectable
1utdB-3u0fA:
undetectable		 1utdA-3u0fA:
10.22
1utdB-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.25A 1utdC-3u0fA:
undetectable
1utdD-3u0fA:
undetectable		 1utdC-3u0fA:
10.22
1utdD-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.25A 1utdG-3u0fA:
undetectable
1utdH-3u0fA:
undetectable		 1utdG-3u0fA:
10.22
1utdH-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.25A 1utdA-3u0fA:
undetectable
1utdK-3u0fA:
undetectable		 1utdA-3u0fA:
10.22
1utdK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		3 / 3 GLN A 341
ILE A 344
TYR A 345
 None
 0.73A 1vifA-3u0fA:
undetectable		 1vifA-3u0fA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		4 / 4 GLY A  50
SER A  34
VAL A 228
LEU A 191
 None
None
None
MOH  A 412 ( 4.0A)
 1.26A 1yajB-3u0fA:
undetectable		 1yajB-3u0fA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 8 GLY A 169
GLY A 259
THR A 399
ALA A 398
ALA A 260
 None
 0.96A 2ej3A-3u0fA:
undetectable		 2ej3A-3u0fA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_B_GBNB914_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 GLY A 169
GLY A 259
THR A 399
ALA A 398
ALA A 260
 None
 0.94A 2ej3B-3u0fA:
undetectable		 2ej3B-3u0fA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		4 / 6 ARG A 277
SER A 271
GLY A 395
THR A 396
 None
 1.15A 2f7fA-3u0fA:
undetectable		 2f7fA-3u0fA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		3 / 3 ASP A 225
ARG A 224
ARG A 218
 None
 1.00A 2j9dA-3u0fA:
undetectable
2j9dC-3u0fA:
undetectable		 2j9dA-3u0fA:
16.53
2j9dC-3u0fA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 ILE A 168
PHE A 227
MET A 205
ALA A  36
LEU A 191
 None
None
None
MOH  A 412 ( 4.9A)
MOH  A 412 ( 4.0A)
 1.32A 2x2nD-3u0fA:
undetectable		 2x2nD-3u0fA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 0.92A 3fhjA-3u0fA:
undetectable		 3fhjA-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 0.89A 3fhjB-3u0fA:
undetectable		 3fhjB-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 0.88A 3fhjC-3u0fA:
undetectable		 3fhjC-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 0.89A 3fhjE-3u0fA:
undetectable		 3fhjE-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 0.92A 3fi0A-3u0fA:
undetectable		 3fi0A-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 0.89A 3fi0C-3u0fA:
undetectable		 3fi0C-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 0.99A 3fi0D-3u0fA:
undetectable		 3fi0D-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 0.90A 3fi0F-3u0fA:
undetectable		 3fi0F-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 0.87A 3fi0H-3u0fA:
undetectable		 3fi0H-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 0.98A 3fi0J-3u0fA:
undetectable		 3fi0J-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 0.90A 3fi0K-3u0fA:
undetectable		 3fi0K-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 1.00A 3fi0L-3u0fA:
undetectable		 3fi0L-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 0.93A 3fi0M-3u0fA:
undetectable		 3fi0M-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 0.87A 3fi0N-3u0fA:
undetectable		 3fi0N-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 0.88A 3fi0O-3u0fA:
undetectable		 3fi0O-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLN A 406
ASP A 291
ILE A 290
VAL A 401
VAL A 256
 None
 1.05A 3fi0R-3u0fA:
undetectable		 3fi0R-3u0fA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 11 ALA A 230
GLY A  71
ILE A 229
SER A 334
LEU A 335
 None
CL  A 408 (-3.4A)
None
None
07L  A 411 (-3.4A)
 1.20A 3gyqB-3u0fA:
undetectable		 3gyqB-3u0fA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 ASP A 304
ARG A 375
LEU A 330
GLY A 332
ALA A 359
 None
 0.99A 3sufA-3u0fA:
undetectable		 3sufA-3u0fA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		3 / 3 ARG A   2
GLU A 242
THR A 243
 None
 0.92A 3v4tA-3u0fA:
undetectable		 3v4tA-3u0fA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		4 / 5 ASP A 263
GLU A 273
GLY A 272
TYR A 265
 None
 1.33A 3w9tB-3u0fA:
undetectable		 3w9tB-3u0fA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		3 / 3 HIS A 333
GLU A 342
ASN A 165
 None
NA  A 410 (-3.1A)
None
 1.00A 4bupB-3u0fA:
undetectable		 4bupB-3u0fA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 ILE A 314
PRO A 322
ILE A 293
LEU A 387
ILE A 290
 None
 1.28A 4dtaA-3u0fA:
undetectable		 4dtaA-3u0fA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 GLY A 336
GLY A 105
THR A 163
ASN A 165
SER A 334
 None
07L  A 411 (-3.3A)
None
None
None
 1.06A 4f84A-3u0fA:
undetectable		 4f84A-3u0fA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		4 / 8 ILE A 355
ALA A 326
PRO A 323
VAL A 386
 None
 0.82A 4jltA-3u0fA:
undetectable		 4jltA-3u0fA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 ASN A  75
GLY A  71
THR A 143
LEU A 144
THR A 111
 None
CL  A 408 (-3.4A)
None
None
None
 1.10A 4k8tB-3u0fA:
undetectable		 4k8tB-3u0fA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 ASN A  75
GLY A  71
THR A 143
LEU A 144
THR A 111
 None
CL  A 408 (-3.4A)
None
None
None
 1.10A 4k93A-3u0fA:
undetectable		 4k93A-3u0fA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 ASN A  75
GLY A  71
THR A 143
LEU A 144
THR A 111
 None
CL  A 408 (-3.4A)
None
None
None
 1.10A 4k93B-3u0fA:
undetectable		 4k93B-3u0fA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 ASN A  75
GLY A  71
THR A 143
LEU A 144
THR A 111
 None
CL  A 408 (-3.4A)
None
None
None
 1.09A 4k9iA-3u0fA:
undetectable		 4k9iA-3u0fA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 ASN A  75
GLY A  71
THR A 143
LEU A 144
THR A 111
 None
CL  A 408 (-3.4A)
None
None
None
 1.10A 4lbxA-3u0fA:
undetectable		 4lbxA-3u0fA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 ASN A  75
GLY A  71
THR A 143
LEU A 144
THR A 111
 None
CL  A 408 (-3.4A)
None
None
None
 1.10A 4lbxB-3u0fA:
undetectable		 4lbxB-3u0fA:
22.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		9 / 12 GLY A 105
ALA A 160
CYH A 161
PHE A 199
HIS A 296
THR A 298
HIS A 333
LEU A 335
GLY A 392
 07L  A 411 (-3.3A)
07L  A 411 (-3.7A)
07L  A 411 (-4.9A)
07L  A 411 (-4.9A)
None
None
None
07L  A 411 (-3.4A)
None
 0.78A 4ls7A-3u0fA:
61.5		 4ls7A-3u0fA:
40.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		9 / 12 GLY A 105
ALA A 160
GLU A 189
PHE A 199
HIS A 296
THR A 298
HIS A 333
LEU A 335
GLY A 392
 07L  A 411 (-3.3A)
07L  A 411 (-3.7A)
07L  A 411 ( 4.0A)
07L  A 411 (-4.9A)
None
None
None
07L  A 411 (-3.4A)
None
 0.70A 4ls7A-3u0fA:
61.5		 4ls7A-3u0fA:
40.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		7 / 12 GLY A 105
ALA A 160
GLU A 189
PHE A 199
LEU A 335
GLY A 392
PHE A 393
 07L  A 411 (-3.3A)
07L  A 411 (-3.7A)
07L  A 411 ( 4.0A)
07L  A 411 (-4.9A)
07L  A 411 (-3.4A)
None
None
 0.58A 4ls7A-3u0fA:
61.5		 4ls7A-3u0fA:
40.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		7 / 12 GLY A 336
ALA A 160
CYH A 161
PHE A 199
HIS A 296
LEU A 335
GLY A 392
 None
07L  A 411 (-3.7A)
07L  A 411 (-4.9A)
07L  A 411 (-4.9A)
None
07L  A 411 (-3.4A)
None
 1.34A 4ls7A-3u0fA:
61.5		 4ls7A-3u0fA:
40.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		8 / 12 ALA A 160
CYH A 161
PHE A 199
HIS A 296
THR A 298
HIS A 333
LEU A 335
GLY A 392
 07L  A 411 (-3.7A)
07L  A 411 (-4.9A)
07L  A 411 (-4.9A)
None
None
None
07L  A 411 (-3.4A)
None
 0.78A 4ls7A-3u0fA:
61.5
4ls7B-3u0fA:
61.1		 4ls7A-3u0fA:
40.82
4ls7B-3u0fA:
40.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 ALA A 160
PHE A 199
LEU A 335
GLY A 392
PHE A 393
 07L  A 411 (-3.7A)
07L  A 411 (-4.9A)
07L  A 411 (-3.4A)
None
None
 0.62A 4ls7A-3u0fA:
61.5
4ls7B-3u0fA:
61.1		 4ls7A-3u0fA:
40.82
4ls7B-3u0fA:
40.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 SER A 196
HIS A 296
THR A 298
HIS A 333
LEU A 335
 MOH  A 412 ( 4.7A)
None
None
None
07L  A 411 (-3.4A)
 1.08A 4ls7A-3u0fA:
61.5
4ls7B-3u0fA:
61.1		 4ls7A-3u0fA:
40.82
4ls7B-3u0fA:
40.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		4 / 6 TYR A 252
GLU A  20
THR A  23
LEU A 348
 MOH  A 413 ( 4.3A)
None
None
None
 1.37A 4qztA-3u0fA:
undetectable		 4qztA-3u0fA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_A_15UA301_1
(THROMBIN HEAVY CHAIN)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 TYR A 258
LEU A 400
ALA A 233
ALA A 185
GLY A 339
 None
 1.40A 4rn6A-3u0fA:
undetectable		 4rn6A-3u0fA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 GLY A 186
GLY A 187
PHE A 184
ALA A 140
ASN A 154
 None
 1.03A 4rtmA-3u0fA:
undetectable		 4rtmA-3u0fA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		4 / 5 THR A 261
GLY A 274
GLU A 307
HIS A 296
 None
 1.05A 5c0oH-3u0fA:
undetectable		 5c0oH-3u0fA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		4 / 5 THR A 143
ALA A 140
THR A 139
HIS A  68
 None
None
CL  A 408 ( 4.9A)
None
 1.39A 5ecmA-3u0fA:
undetectable		 5ecmA-3u0fA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.25A 5eeuA-3u0fA:
undetectable
5eeuB-3u0fA:
undetectable		 5eeuA-3u0fA:
10.22
5eeuB-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 5eeuB-3u0fA:
undetectable
5eeuC-3u0fA:
undetectable		 5eeuB-3u0fA:
10.22
5eeuC-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.24A 5eeuE-3u0fA:
undetectable
5eeuF-3u0fA:
undetectable		 5eeuE-3u0fA:
10.22
5eeuF-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.27A 5eeuG-3u0fA:
undetectable
5eeuH-3u0fA:
undetectable		 5eeuG-3u0fA:
10.22
5eeuH-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.22A 5eeuH-3u0fA:
undetectable
5eeuI-3u0fA:
undetectable		 5eeuH-3u0fA:
10.22
5eeuI-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5eeuJ-3u0fA:
undetectable
5eeuK-3u0fA:
undetectable		 5eeuJ-3u0fA:
10.22
5eeuK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.24A 5eeuA-3u0fA:
undetectable
5eeuK-3u0fA:
undetectable		 5eeuA-3u0fA:
10.22
5eeuK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 5eevB-3u0fA:
undetectable
5eevC-3u0fA:
undetectable		 5eevB-3u0fA:
10.22
5eevC-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.25A 5eevE-3u0fA:
undetectable
5eevF-3u0fA:
undetectable		 5eevE-3u0fA:
10.22
5eevF-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.27A 5eevG-3u0fA:
undetectable
5eevH-3u0fA:
undetectable		 5eevG-3u0fA:
10.22
5eevH-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.22A 5eevH-3u0fA:
undetectable
5eevI-3u0fA:
undetectable		 5eevH-3u0fA:
10.22
5eevI-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5eevJ-3u0fA:
undetectable
5eevK-3u0fA:
undetectable		 5eevJ-3u0fA:
10.22
5eevK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.24A 5eevA-3u0fA:
undetectable
5eevK-3u0fA:
undetectable		 5eevA-3u0fA:
10.22
5eevK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.33A 5eevU-3u0fA:
undetectable
5eevV-3u0fA:
undetectable		 5eevU-3u0fA:
10.22
5eevV-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 5eewB-3u0fA:
undetectable
5eewC-3u0fA:
undetectable		 5eewB-3u0fA:
10.22
5eewC-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.25A 5eewE-3u0fA:
undetectable
5eewF-3u0fA:
undetectable		 5eewE-3u0fA:
10.22
5eewF-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.27A 5eewG-3u0fA:
undetectable
5eewH-3u0fA:
undetectable		 5eewG-3u0fA:
10.22
5eewH-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.22A 5eewH-3u0fA:
undetectable
5eewI-3u0fA:
undetectable		 5eewH-3u0fA:
10.22
5eewI-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5eewJ-3u0fA:
undetectable
5eewK-3u0fA:
undetectable		 5eewJ-3u0fA:
10.22
5eewK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.24A 5eewA-3u0fA:
undetectable
5eewK-3u0fA:
undetectable		 5eewA-3u0fA:
10.22
5eewK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 5eexB-3u0fA:
undetectable
5eexC-3u0fA:
undetectable		 5eexB-3u0fA:
10.22
5eexC-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.25A 5eexE-3u0fA:
undetectable
5eexF-3u0fA:
undetectable		 5eexE-3u0fA:
10.22
5eexF-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.27A 5eexG-3u0fA:
undetectable
5eexH-3u0fA:
undetectable		 5eexG-3u0fA:
10.22
5eexH-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5eexH-3u0fA:
undetectable
5eexI-3u0fA:
undetectable		 5eexH-3u0fA:
10.22
5eexI-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 11 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 5eexI-3u0fA:
undetectable
5eexJ-3u0fA:
undetectable		 5eexI-3u0fA:
10.22
5eexJ-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5eexJ-3u0fA:
undetectable
5eexK-3u0fA:
undetectable		 5eexJ-3u0fA:
10.22
5eexK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.25A 5eexA-3u0fA:
undetectable
5eexK-3u0fA:
undetectable		 5eexA-3u0fA:
10.22
5eexK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.33A 5eexU-3u0fA:
undetectable
5eexV-3u0fA:
undetectable		 5eexU-3u0fA:
10.22
5eexV-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 5eeyB-3u0fA:
undetectable
5eeyC-3u0fA:
undetectable		 5eeyB-3u0fA:
10.22
5eeyC-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.25A 5eeyE-3u0fA:
undetectable
5eeyF-3u0fA:
undetectable		 5eeyE-3u0fA:
10.22
5eeyF-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.28A 5eeyG-3u0fA:
undetectable
5eeyH-3u0fA:
undetectable		 5eeyG-3u0fA:
10.22
5eeyH-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5eeyH-3u0fA:
undetectable
5eeyI-3u0fA:
undetectable		 5eeyH-3u0fA:
10.22
5eeyI-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 11 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.27A 5eeyI-3u0fA:
undetectable
5eeyJ-3u0fA:
undetectable		 5eeyI-3u0fA:
10.22
5eeyJ-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5eeyJ-3u0fA:
undetectable
5eeyK-3u0fA:
undetectable		 5eeyJ-3u0fA:
10.22
5eeyK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.24A 5eeyA-3u0fA:
undetectable
5eeyK-3u0fA:
undetectable		 5eeyA-3u0fA:
10.22
5eeyK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 5eezB-3u0fA:
undetectable
5eezC-3u0fA:
undetectable		 5eezB-3u0fA:
10.22
5eezC-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.25A 5eezE-3u0fA:
undetectable
5eezF-3u0fA:
undetectable		 5eezE-3u0fA:
10.22
5eezF-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.28A 5eezG-3u0fA:
undetectable
5eezH-3u0fA:
undetectable		 5eezG-3u0fA:
10.22
5eezH-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5eezH-3u0fA:
undetectable
5eezI-3u0fA:
undetectable		 5eezH-3u0fA:
10.22
5eezI-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 11 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.27A 5eezI-3u0fA:
undetectable
5eezJ-3u0fA:
undetectable		 5eezI-3u0fA:
10.22
5eezJ-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5eezJ-3u0fA:
undetectable
5eezK-3u0fA:
undetectable		 5eezJ-3u0fA:
10.22
5eezK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.25A 5eezA-3u0fA:
undetectable
5eezK-3u0fA:
undetectable		 5eezA-3u0fA:
10.22
5eezK-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 5ef0B-3u0fA:
undetectable
5ef0C-3u0fA:
undetectable		 5ef0B-3u0fA:
10.22
5ef0C-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 5ef0E-3u0fA:
undetectable
5ef0F-3u0fA:
undetectable		 5ef0E-3u0fA:
10.22
5ef0F-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.28A 5ef0G-3u0fA:
undetectable
5ef0H-3u0fA:
undetectable		 5ef0G-3u0fA:
10.22
5ef0H-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5ef0H-3u0fA:
undetectable
5ef0I-3u0fA:
undetectable		 5ef0H-3u0fA:
10.22
5ef0I-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 11 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.27A 5ef0I-3u0fA:
undetectable
5ef0J-3u0fA:
undetectable		 5ef0I-3u0fA:
10.22
5ef0J-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5ef0J-3u0fA:
undetectable
5ef0K-3u0fA:
undetectable		 5ef0J-3u0fA:
10.22
5ef0K-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.24A 5ef0A-3u0fA:
undetectable
5ef0K-3u0fA:
undetectable		 5ef0A-3u0fA:
10.22
5ef0K-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 5ef1B-3u0fA:
undetectable
5ef1C-3u0fA:
undetectable		 5ef1B-3u0fA:
10.22
5ef1C-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 5ef1E-3u0fA:
undetectable
5ef1F-3u0fA:
undetectable		 5ef1E-3u0fA:
10.22
5ef1F-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.28A 5ef1G-3u0fA:
undetectable
5ef1H-3u0fA:
undetectable		 5ef1G-3u0fA:
10.22
5ef1H-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5ef1H-3u0fA:
undetectable
5ef1I-3u0fA:
undetectable		 5ef1H-3u0fA:
10.22
5ef1I-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 11 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.27A 5ef1I-3u0fA:
undetectable
5ef1J-3u0fA:
undetectable		 5ef1I-3u0fA:
10.22
5ef1J-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5ef1J-3u0fA:
undetectable
5ef1K-3u0fA:
undetectable		 5ef1J-3u0fA:
10.22
5ef1K-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.25A 5ef1A-3u0fA:
undetectable
5ef1K-3u0fA:
undetectable		 5ef1A-3u0fA:
10.22
5ef1K-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 5ef2B-3u0fA:
undetectable
5ef2C-3u0fA:
undetectable		 5ef2B-3u0fA:
10.22
5ef2C-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 5ef2E-3u0fA:
undetectable
5ef2F-3u0fA:
undetectable		 5ef2E-3u0fA:
10.22
5ef2F-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.28A 5ef2G-3u0fA:
undetectable
5ef2H-3u0fA:
undetectable		 5ef2G-3u0fA:
10.22
5ef2H-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5ef2H-3u0fA:
undetectable
5ef2I-3u0fA:
undetectable		 5ef2H-3u0fA:
10.22
5ef2I-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 11 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.27A 5ef2I-3u0fA:
undetectable
5ef2J-3u0fA:
undetectable		 5ef2I-3u0fA:
10.22
5ef2J-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5ef2J-3u0fA:
undetectable
5ef2K-3u0fA:
undetectable		 5ef2J-3u0fA:
10.22
5ef2K-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.25A 5ef2A-3u0fA:
undetectable
5ef2K-3u0fA:
undetectable		 5ef2A-3u0fA:
10.22
5ef2K-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.26A 5ef3B-3u0fA:
undetectable
5ef3C-3u0fA:
undetectable		 5ef3B-3u0fA:
10.22
5ef3C-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.25A 5ef3E-3u0fA:
undetectable
5ef3F-3u0fA:
undetectable		 5ef3E-3u0fA:
10.22
5ef3F-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.28A 5ef3G-3u0fA:
undetectable
5ef3H-3u0fA:
undetectable		 5ef3G-3u0fA:
10.22
5ef3H-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5ef3H-3u0fA:
undetectable
5ef3I-3u0fA:
undetectable		 5ef3H-3u0fA:
10.22
5ef3I-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 11 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.27A 5ef3I-3u0fA:
undetectable
5ef3J-3u0fA:
undetectable		 5ef3I-3u0fA:
10.22
5ef3J-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 THR A 338
GLY A 332
HIS A 333
ALA A 326
THR A 331
 None
 1.23A 5ef3J-3u0fA:
undetectable
5ef3K-3u0fA:
undetectable		 5ef3J-3u0fA:
10.22
5ef3K-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 10 GLY A 332
HIS A 333
ALA A 326
THR A 331
THR A 338
 None
 1.24A 5ef3A-3u0fA:
undetectable
5ef3K-3u0fA:
undetectable		 5ef3A-3u0fA:
10.22
5ef3K-3u0fA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 ILE A 100
GLY A  99
THR A  98
LEU A 144
VAL A 235
 None
 1.09A 5hw4A-3u0fA:
undetectable		 5hw4A-3u0fA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 ILE A 100
GLY A  99
THR A  98
LEU A 144
VAL A 235
 None
 1.10A 5hw4C-3u0fA:
undetectable		 5hw4C-3u0fA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		4 / 5 GLU A 342
GLY A 332
SER A 334
GLY A 231
 NA  A 410 (-3.1A)
None
None
None
 1.11A 5kprA-3u0fA:
undetectable		 5kprA-3u0fA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 9 ARG A  97
ILE A 101
GLY A 152
LEU A 238
ALA A 171
 None
 0.95A 5o96A-3u0fA:
undetectable
5o96B-3u0fA:
undetectable		 5o96A-3u0fA:
20.99
5o96B-3u0fA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		3 / 3 HIS A 333
GLU A 342
ASN A 165
 None
NA  A 410 (-3.1A)
None
 0.94A 5wbvA-3u0fA:
undetectable		 5wbvA-3u0fA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		3 / 3 HIS A 333
GLU A 342
ASN A 165
 None
NA  A 410 (-3.1A)
None
 0.94A 5wbvB-3u0fA:
undetectable		 5wbvB-3u0fA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		4 / 6 SER A  14
ALA A 337
ALA A 230
SER A 334
 None
 0.98A 6bocA-3u0fA:
undetectable
6bocB-3u0fA:
undetectable
6bocC-3u0fA:
undetectable
6bocD-3u0fA:
undetectable		 6bocA-3u0fA:
4.94
6bocB-3u0fA:
4.94
6bocC-3u0fA:
4.94
6bocD-3u0fA:
4.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3u0f BETA-KETOACYL
SYNTHASE
(Brucella
abortus) 		5 / 12 TYR A 292
VAL A 374
ILE A 373
TYR A 220
ILE A  15
 None
 1.29A 6mkeA-3u0fA:
undetectable
6mkeD-3u0fA:
undetectable		 6mkeA-3u0fA:
10.71
6mkeD-3u0fA:
10.71