SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u0j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 9 ILE B  89
PHE B  71
VAL B  81
ALA B 148
LEU B 152
 None
 0.86A 1e7bA-3u0jB:
undetectable		 1e7bA-3u0jB:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 PHE B  71
VAL B  81
ALA B 148
LEU B 152
 None
 0.55A 1e7bB-3u0jB:
undetectable		 1e7bB-3u0jB:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 PHE B 214
ILE B 166
HIS B 257
LEU B 176
 None
 0.80A 1fslB-3u0jB:
undetectable		 1fslB-3u0jB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 TYR B 186
GLU B 188
ASN B 116
 None
 1.01A 2y7hC-3u0jB:
undetectable		 2y7hC-3u0jB:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 PRO B 239
MET B 241
SER B 242
LEU B 118
 None
 1.07A 3lsfH-3u0jB:
undetectable		 3lsfH-3u0jB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 9 PHE B 214
VAL B 203
ASN B 210
ILE B 166
GLY B 168
 None
 1.37A 3t3rB-3u0jB:
undetectable		 3t3rB-3u0jB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 9 PHE B 214
VAL B 203
ASN B 210
ILE B 166
GLY B 168
 None
 1.39A 3t3rC-3u0jB:
undetectable		 3t3rC-3u0jB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 PHE B 214
VAL B 203
ASN B 210
ILE B 166
GLY B 168
 None
 1.36A 3t3rD-3u0jB:
undetectable		 3t3rD-3u0jB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 PHE B 244
GLY B 221
ILE B 216
VAL B 162
 None
 0.74A 3wrkA-3u0jB:
0.8		 3wrkA-3u0jB:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 MET B 144
MET B 153
TYR B  82
 None
 1.16A 4p6xI-3u0jB:
undetectable		 4p6xI-3u0jB:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 PHE B 204
ALA B 213
GLN B 215
THR B 161
ARG B 164
 None
 1.26A 4qzuB-3u0jB:
undetectable		 4qzuB-3u0jB:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 ARG B 164
SER B 193
GLU B 233
GLU B 235
 None
 0.81A 4xzkA-3u0jB:
14.0		 4xzkA-3u0jB:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 PRO B 239
HIS B 141
TYR B  78
PHE B  66
 None
 1.47A 5igjA-3u0jB:
undetectable		 5igjA-3u0jB:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 4 ASN B 211
ILE B 216
TYR B 186
PHE B 180
 None
 1.02A 5igvA-3u0jB:
undetectable		 5igvA-3u0jB:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ALA B 156
VAL B 155
GLU B 235
ALA B  88
ALA B 148
 None
 0.92A 5n5dB-3u0jB:
undetectable		 5n5dB-3u0jB:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 PRO B 109
GLY B 107
LEU B  57
ASP B  61
ASP B  51
 None
 1.22A 5yn6A-3u0jB:
undetectable		 5yn6A-3u0jB:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 PRO B 109
GLY B 107
LEU B  57
ASP B  61
ASP B  51
 None
 1.23A 5yniA-3u0jB:
undetectable		 5yniA-3u0jB:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 ARG B 164
GLY B 165
SER B 193
THR B 195
 None
 0.83A 5ysiA-3u0jB:
9.6		 5ysiA-3u0jB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 PRO B 239
MET B 241
SER B 242
LEU B 145
LEU B 118
 None
 0.95A 6dlzA-3u0jB:
undetectable
6dlzD-3u0jB:
undetectable		 6dlzA-3u0jB:
14.83
6dlzD-3u0jB:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3u0j TYPE III EFFECTOR
HOPU1
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 PRO B 239
MET B 241
SER B 242
LEU B 145
LEU B 118
 None
 0.95A 6dm1A-3u0jB:
undetectable
6dm1D-3u0jB:
undetectable		 6dm1A-3u0jB:
14.83
6dm1D-3u0jB:
14.83