SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u0k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A29_A_TFPA154_1
(CALMODULIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		6 / 10 LEU A 312
MET A 403
GLU A 408
LEU A 410
GLU A 414
MET A 418
 None
 1.03A 1a29A-3u0kA:
17.8		 1a29A-3u0kA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CTR_A_TFPA153_1
(CALMODULIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 9 ILE A 321
LEU A 326
MET A 345
GLU A 348
MET A 365
 None
 0.77A 1ctrA-3u0kA:
17.3		 1ctrA-3u0kA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CTR_A_TFPA153_1
(CALMODULIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 9 ILE A 394
LEU A 399
GLU A 421
ALA A 422
VAL A 430
 None
 1.20A 1ctrA-3u0kA:
17.3		 1ctrA-3u0kA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CTR_A_TFPA153_1
(CALMODULIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 9 ILE A 394
LEU A 399
MET A 418
ALA A 422
VAL A 430
 None
 0.65A 1ctrA-3u0kA:
17.3		 1ctrA-3u0kA:
38.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 3u0k RCAMP
(Entacmaea
quadricolor) 		7 / 11 PHE A 313
ILE A 321
LEU A 326
LEU A 333
MET A 345
VAL A 349
MET A 365
 None
 0.67A 1dtlA-3u0kA:
14.5		 1dtlA-3u0kA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 3u0k RCAMP
(Entacmaea
quadricolor) 		7 / 11 PHE A 313
ILE A 321
LEU A 326
MET A 330
MET A 345
VAL A 349
MET A 365
 None
 0.76A 1dtlA-3u0kA:
14.5		 1dtlA-3u0kA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 3u0k RCAMP
(Entacmaea
quadricolor) 		6 / 11 PHE A 386
ILE A 394
LEU A 399
MET A 403
LEU A 406
MET A 418
 None
 0.68A 1dtlA-3u0kA:
14.5		 1dtlA-3u0kA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 8 MET A 330
GLN A 335
PRO A 337
GLU A 341
 None
 0.88A 1dtlA-3u0kA:
14.5		 1dtlA-3u0kA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 6 PHE A 313
ILE A 346
ALA A  52
MET A 366
 None
 1.24A 1hk2A-3u0kA:
undetectable		 1hk2A-3u0kA:
18.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIN_A_TFPA154_1
(CALMODULIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		6 / 7 LEU A 312
MET A 403
GLU A 408
LEU A 410
GLU A 414
MET A 418
 None
 1.01A 1linA-3u0kA:
17.9		 1linA-3u0kA:
38.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		6 / 12 ILE A 321
LEU A 326
MET A 330
ILE A 346
MET A 365
MET A 366
 None
 1.18A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		6 / 12 PHE A 313
ILE A 321
LEU A 326
MET A 330
ILE A 346
MET A 366
 None
 1.01A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		6 / 12 PHE A 313
LEU A 326
MET A 330
ILE A 346
GLU A 348
MET A 366
 None
 1.21A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		8 / 12 PHE A 386
ILE A 394
LEU A 399
LEU A 406
GLU A 421
VAL A 430
MET A 438
MET A 439
 None
 1.02A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		8 / 12 PHE A 386
ILE A 394
LEU A 399
LEU A 406
ILE A 419
GLU A 421
VAL A 430
MET A 439
 None
 1.03A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		8 / 12 PHE A 386
ILE A 394
LEU A 399
LEU A 406
MET A 418
ILE A 419
VAL A 430
MET A 439
 None
 0.99A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		8 / 12 PHE A 386
ILE A 394
LEU A 399
MET A 403
LEU A 406
GLU A 421
VAL A 430
MET A 438
 None
 1.05A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		8 / 12 PHE A 386
ILE A 394
LEU A 399
MET A 403
LEU A 406
ILE A 419
GLU A 421
VAL A 430
 None
 1.08A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		8 / 12 PHE A 386
ILE A 394
LEU A 399
MET A 403
LEU A 406
MET A 418
ILE A 419
VAL A 430
 None
 1.04A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 7 LEU A 410
LEU A 399
LEU A 406
GLY A 407
 None
 0.89A 1n13D-3u0kA:
undetectable
1n13E-3u0kA:
undetectable		 1n13D-3u0kA:
11.54
1n13E-3u0kA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA202_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 10 LEU A 333
MET A 345
MET A 365
GLU A 378
ALA A 382
 None
 1.27A 1wrkA-3u0kA:
10.3
1wrkB-3u0kA:
10.1		 1wrkA-3u0kA:
16.53
1wrkB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA202_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 10 MET A 345
MET A 365
MET A 366
GLU A 378
ALA A 382
 None
 1.07A 1wrkA-3u0kA:
10.3
1wrkB-3u0kA:
10.1		 1wrkA-3u0kA:
16.53
1wrkB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 9 PHE A 386
VAL A 402
LEU A 406
PHE A 435
LEU A 333
 None
 1.11A 1wrkA-3u0kA:
10.3
1wrkB-3u0kA:
10.1		 1wrkA-3u0kA:
16.53
1wrkB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 9 VAL A 402
LEU A 406
PHE A 435
MET A 439
LEU A 333
 None
 0.66A 1wrkA-3u0kA:
10.3
1wrkB-3u0kA:
10.1		 1wrkA-3u0kA:
16.53
1wrkB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB201_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 10 GLU A 378
ALA A 382
LEU A 333
MET A 345
MET A 366
 None
 1.31A 1wrkA-3u0kA:
10.3
1wrkB-3u0kA:
10.1		 1wrkA-3u0kA:
16.53
1wrkB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB201_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 10 GLU A 378
ALA A 382
LEU A 333
MET A 365
MET A 366
 None
 0.92A 1wrkA-3u0kA:
10.3
1wrkB-3u0kA:
10.1		 1wrkA-3u0kA:
16.53
1wrkB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB201_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 10 GLU A 378
ALA A 382
MET A 330
LEU A 333
MET A 345
 None
 0.86A 1wrkA-3u0kA:
10.3
1wrkB-3u0kA:
10.1		 1wrkA-3u0kA:
16.53
1wrkB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 5 PHE A 313
LEU A 333
PHE A 362
MET A 366
 None
 1.13A 1wrkB-3u0kA:
10.1		 1wrkB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA202_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 9 MET A 330
LEU A 333
GLU A 341
MET A 345
ALA A 382
 None
 0.86A 1wrlA-3u0kA:
10.4
1wrlB-3u0kA:
10.4		 1wrlA-3u0kA:
16.53
1wrlB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA202_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 9 MET A 330
LEU A 333
GLU A 341
MET A 365
ALA A 382
 None
 1.18A 1wrlA-3u0kA:
10.4
1wrlB-3u0kA:
10.4		 1wrlA-3u0kA:
16.53
1wrlB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA202_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 9 MET A 330
LEU A 333
MET A 345
GLU A 378
ALA A 382
 None
 1.01A 1wrlA-3u0kA:
10.4
1wrlB-3u0kA:
10.4		 1wrlA-3u0kA:
16.53
1wrlB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA202_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 9 MET A 330
LEU A 333
MET A 365
GLU A 378
ALA A 382
 None
 1.45A 1wrlA-3u0kA:
10.4
1wrlB-3u0kA:
10.4		 1wrlA-3u0kA:
16.53
1wrlB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 7 PHE A 313
LEU A 333
PHE A 362
MET A 366
 None
 1.12A 1wrlA-3u0kA:
10.4
1wrlB-3u0kA:
10.4		 1wrlA-3u0kA:
16.53
1wrlB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB201_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 9 MET A 330
LEU A 333
GLN A 335
MET A 345
MET A 365
 None
 1.03A 1wrlA-3u0kA:
10.4
1wrlB-3u0kA:
10.4		 1wrlA-3u0kA:
16.53
1wrlB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB201_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		6 / 9 MET A 330
LEU A 333
GLU A 341
MET A 345
MET A 365
MET A 366
 None
 0.94A 1wrlA-3u0kA:
10.4
1wrlB-3u0kA:
10.4		 1wrlA-3u0kA:
16.53
1wrlB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 6 PHE A 313
VAL A 329
LEU A 333
PHE A 362
MET A 366
 None
 1.25A 1wrlB-3u0kA:
10.4		 1wrlB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 6 VAL A 402
LEU A 406
PHE A 435
MET A 439
 None
 0.60A 1wrlB-3u0kA:
10.4		 1wrlB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC206_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 9 LEU A 333
MET A 345
MET A 365
MET A 366
GLU A 378
 None
 1.43A 1wrlC-3u0kA:
10.3
1wrlD-3u0kA:
9.9		 1wrlC-3u0kA:
16.53
1wrlD-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC206_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		6 / 9 MET A 330
GLN A 335
GLU A 341
MET A 345
MET A 365
MET A 366
 None
 1.13A 1wrlC-3u0kA:
10.3
1wrlD-3u0kA:
9.9		 1wrlC-3u0kA:
16.53
1wrlD-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC206_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		6 / 9 MET A 330
LEU A 333
GLU A 341
MET A 345
MET A 365
MET A 366
 None
 0.99A 1wrlC-3u0kA:
10.3
1wrlD-3u0kA:
9.9		 1wrlC-3u0kA:
16.53
1wrlD-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 5 PHE A 313
LEU A 333
PHE A 362
MET A 366
 None
 1.02A 1wrlC-3u0kA:
10.3		 1wrlC-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD205_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 10 ALA A 382
LEU A 333
MET A 345
MET A 365
MET A 366
 None
 1.10A 1wrlC-3u0kA:
10.3
1wrlD-3u0kA:
9.9		 1wrlC-3u0kA:
16.53
1wrlD-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD205_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 10 GLU A 378
ALA A 382
LEU A 333
MET A 345
MET A 365
 None
 1.36A 1wrlC-3u0kA:
10.3
1wrlD-3u0kA:
9.9		 1wrlC-3u0kA:
16.53
1wrlD-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD205_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 10 GLU A 378
ALA A 382
MET A 330
LEU A 333
MET A 345
 None
 0.89A 1wrlC-3u0kA:
10.3
1wrlD-3u0kA:
9.9		 1wrlC-3u0kA:
16.53
1wrlD-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD205_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 10 LEU A 333
GLU A 341
MET A 345
MET A 365
MET A 366
 None
 1.05A 1wrlC-3u0kA:
10.3
1wrlD-3u0kA:
9.9		 1wrlC-3u0kA:
16.53
1wrlD-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE210_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 9 LEU A 333
MET A 345
MET A 365
GLU A 378
ALA A 382
 None
 1.38A 1wrlE-3u0kA:
10.3
1wrlF-3u0kA:
10.2		 1wrlE-3u0kA:
16.53
1wrlF-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE210_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 9 MET A 330
GLN A 335
GLU A 341
MET A 345
MET A 365
 None
 1.14A 1wrlE-3u0kA:
10.3
1wrlF-3u0kA:
10.2		 1wrlE-3u0kA:
16.53
1wrlF-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE210_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 9 MET A 330
LEU A 333
GLU A 341
MET A 345
MET A 365
 None
 0.93A 1wrlE-3u0kA:
10.3
1wrlF-3u0kA:
10.2		 1wrlE-3u0kA:
16.53
1wrlF-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 7 PHE A 306
PHE A 313
LEU A 333
PHE A 362
MET A 366
 None
 1.16A 1wrlE-3u0kA:
10.3		 1wrlE-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF209_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 10 GLU A 378
MET A 330
LEU A 333
MET A 345
MET A 365
 None
 1.47A 1wrlE-3u0kA:
10.3
1wrlF-3u0kA:
10.2		 1wrlE-3u0kA:
16.53
1wrlF-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF209_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		7 / 10 MET A 330
LEU A 333
GLN A 335
GLU A 341
MET A 345
MET A 365
MET A 366
 None
 1.00A 1wrlE-3u0kA:
10.3
1wrlF-3u0kA:
10.2		 1wrlE-3u0kA:
16.53
1wrlF-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 7 LEU A 333
LEU A 406
PHE A 435
MET A 439
 None
 0.78A 1wrlE-3u0kA:
10.3
1wrlF-3u0kA:
10.2		 1wrlE-3u0kA:
16.53
1wrlF-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 8 ALA A  52
ALA A 309
SER A 332
VAL A 329
 None
 0.66A 2bxgA-3u0kA:
undetectable		 2bxgA-3u0kA:
18.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2N27_A_4DYA205_1
(CALMODULIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		6 / 11 ILE A 321
MET A 365
MET A 366
VAL A 402
MET A 403
MET A 439
 None
 1.20A 2n27A-3u0kA:
3.1		 2n27A-3u0kA:
38.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 12 ARG A  55
LEU A 326
ALA A 340
THR A 338
GLU A 378
 None
 1.26A 2v0mC-3u0kA:
undetectable		 2v0mC-3u0kA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 12 LEU A 117
GLN A 257
LEU A 166
TYR A 247
THR A  76
 CRK  A 214 ( 4.2A)
NFA  A 213 ( 3.8A)
NFA  A 213 ( 3.7A)
None
CRK  A 214 ( 4.6A)
 1.04A 2w3mA-3u0kA:
undetectable		 2w3mA-3u0kA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_B_FOLB1188_0
(DIHYDROFOLATE
REDUCTASE)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 12 LEU A 117
GLN A 257
LEU A 166
TYR A 247
THR A  76
 CRK  A 214 ( 4.2A)
NFA  A 213 ( 3.8A)
NFA  A 213 ( 3.7A)
None
CRK  A 214 ( 4.6A)
 0.99A 2w3mB-3u0kA:
undetectable		 2w3mB-3u0kA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 11 GLY A 251
TYR A 247
PHE A 277
GLY A 274
ILE A 253
 None
 1.12A 2y7kA-3u0kA:
undetectable		 2y7kA-3u0kA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 12 GLY A 251
TYR A 247
PHE A 277
GLY A 274
ILE A 253
 None
 1.16A 2y7kC-3u0kA:
undetectable		 2y7kC-3u0kA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 5 ILE A 394
ARG A  40
MET A 439
THR A 440
 None
 1.40A 3abkN-3u0kA:
undetectable
3abkW-3u0kA:
undetectable		 3abkN-3u0kA:
20.60
3abkW-3u0kA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 3u0k RCAMP
(Entacmaea
quadricolor) 		3 / 3 HIS A 134
GLU A 133
HIS A 115
 None
ACT  A 443 (-2.7A)
CRK  A 214 (-3.4A)
 0.87A 3ba0A-3u0kA:
undetectable		 3ba0A-3u0kA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3u0k RCAMP
(Entacmaea
quadricolor) 		3 / 3 VAL A 402
SER A 332
LEU A 406
 None
 0.69A 3n8xA-3u0kA:
undetectable		 3n8xA-3u0kA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 6 PHE A 206
HIS A 269
VAL A 255
PHE A 175
 NFA  A 213 ( 4.7A)
None
None
None
 1.01A 4a97E-3u0kA:
undetectable		 4a97E-3u0kA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRI_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 10 LEU A 363
ARG A 368
THR A 320
ASP A 314
PHE A 306
 None
None
None
CA  A 447 (-3.7A)
None
 1.33A 4driB-3u0kA:
0.0		 4driB-3u0kA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 8 ASP A 350
ASP A 352
GLU A 325
GLU A 339
 CA  A 446 (-3.3A)
CA  A 446 (-3.0A)
CA  A 447 (-2.1A)
None
 1.07A 4feuD-3u0kA:
undetectable		 4feuD-3u0kA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 12 LEU A 117
GLN A 257
LEU A 166
TYR A 247
THR A  76
 CRK  A 214 ( 4.2A)
NFA  A 213 ( 3.8A)
NFA  A 213 ( 3.7A)
None
CRK  A 214 ( 4.6A)
 1.03A 4kebB-3u0kA:
undetectable		 4kebB-3u0kA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 5 GLY A 188
ALA A 135
PHE A 220
GLU A 133
 None
ACT  A 443 (-3.5A)
None
ACT  A 443 (-2.7A)
 1.01A 4m93B-3u0kA:
undetectable
4m93C-3u0kA:
undetectable		 4m93B-3u0kA:
18.45
4m93C-3u0kA:
17.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 8 ILE A 321
LEU A 326
MET A 345
MET A 365
 None
 0.51A 4rjdA-3u0kA:
13.7		 4rjdA-3u0kA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 8 PHE A 313
ILE A 321
LEU A 326
MET A 345
 None
 0.47A 4rjdA-3u0kA:
13.7		 4rjdA-3u0kA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 8 PHE A 386
ILE A 394
LEU A 399
MET A 403
VAL A 430
 None
 0.49A 4rjdA-3u0kA:
13.7		 4rjdA-3u0kA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		6 / 8 PHE A 386
ILE A 394
LEU A 399
MET A 418
ALA A 422
VAL A 430
 None
 0.43A 4rjdA-3u0kA:
13.7		 4rjdA-3u0kA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 7 PHE A 313
LEU A 326
MET A 345
MET A 365
MET A 366
 None
 0.62A 4rjdB-3u0kA:
13.3		 4rjdB-3u0kA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 7 PHE A 386
LEU A 399
MET A 418
ALA A 422
 None
 0.48A 4rjdB-3u0kA:
13.3		 4rjdB-3u0kA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 5 ALA A 135
ARG A 218
ALA A 137
GLU A  63
 ACT  A 443 (-3.5A)
ACT  A 443 (-3.6A)
None
CRK  A 214 ( 4.1A)
 1.06A 5a06C-3u0kA:
undetectable
5a06D-3u0kA:
undetectable		 5a06C-3u0kA:
21.56
5a06D-3u0kA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 3u0k RCAMP
(Entacmaea
quadricolor) 		5 / 10 LEU A 326
MET A 345
VAL A 349
ILE A 357
MET A 366
 None
 0.75A 5v02B-3u0kA:
undetectable
5v02R-3u0kA:
11.4		 5v02B-3u0kA:
12.05
5v02R-3u0kA:
33.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3u0k RCAMP
(Entacmaea
quadricolor) 		4 / 6 PHE A 277
PRO A 278
GLY A 281
ASN A 280
 None
 0.92A 5x24A-3u0kA:
undetectable		 5x24A-3u0kA:
19.88