SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u15'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 7 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.85A 1v54N-3u15A:
undetectable
1v54W-3u15A:
undetectable		 1v54N-3u15A:
11.22
1v54W-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 7 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.86A 1v55A-3u15A:
undetectable
1v55J-3u15A:
undetectable		 1v55A-3u15A:
11.22
1v55J-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		5 / 11 VAL A  74
PHE A  90
GLY A  57
ILE A  36
LEU A  81
 None
None
03M  A   1 ( 4.0A)
None
None
 1.06A 1z11A-3u15A:
undetectable		 1z11A-3u15A:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		5 / 11 VAL A  74
PHE A  90
GLY A  57
ILE A  36
LEU A  81
 None
None
03M  A   1 ( 4.0A)
None
None
 1.03A 1z11B-3u15A:
undetectable		 1z11B-3u15A:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 7 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.81A 2dyrN-3u15A:
undetectable
2dyrW-3u15A:
undetectable		 2dyrN-3u15A:
11.22
2dyrW-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 8 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.88A 2eijN-3u15A:
undetectable
2eijW-3u15A:
undetectable		 2eijN-3u15A:
11.22
2eijW-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 8 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.84A 2eikN-3u15A:
undetectable
2eikW-3u15A:
undetectable		 2eikN-3u15A:
11.22
2eikW-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 8 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.84A 2eilN-3u15A:
undetectable
2eilW-3u15A:
undetectable		 2eilN-3u15A:
11.22
2eilW-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 6 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.76A 2einN-3u15A:
undetectable
2einW-3u15A:
undetectable		 2einN-3u15A:
11.22
2einW-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 7 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.79A 3ablA-3u15A:
undetectable
3ablJ-3u15A:
undetectable		 3ablA-3u15A:
11.22
3ablJ-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 8 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.80A 3ablN-3u15A:
undetectable
3ablW-3u15A:
undetectable		 3ablN-3u15A:
11.22
3ablW-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 6 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.95A 3ag1N-3u15A:
undetectable
3ag1W-3u15A:
undetectable		 3ag1N-3u15A:
11.22
3ag1W-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 7 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.81A 3ag3A-3u15A:
undetectable
3ag3J-3u15A:
undetectable		 3ag3A-3u15A:
11.22
3ag3J-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 8 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.78A 3ag3N-3u15A:
undetectable
3ag3W-3u15A:
undetectable		 3ag3N-3u15A:
11.22
3ag3W-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 8 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.87A 3asnN-3u15A:
undetectable
3asnW-3u15A:
undetectable		 3asnN-3u15A:
11.22
3asnW-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		3 / 3 GLY A  44
PRO A  29
LEU A  37
 None
 0.62A 3hcpB-3u15A:
undetectable		 3hcpB-3u15A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 6 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.95A 3wg7N-3u15A:
undetectable
3wg7W-3u15A:
undetectable		 3wg7N-3u15A:
11.22
3wg7W-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 7 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.91A 5b3sN-3u15A:
undetectable
5b3sW-3u15A:
undetectable		 5b3sN-3u15A:
11.22
5b3sW-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 7 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.89A 5iy5A-3u15A:
undetectable
5iy5J-3u15A:
undetectable		 5iy5A-3u15A:
11.22
5iy5J-3u15A:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 7 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.83A 5iy5N-3u15A:
undetectable
5iy5W-3u15A:
undetectable		 5iy5N-3u15A:
11.22
5iy5W-3u15A:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 7 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.86A 5xdxA-3u15A:
undetectable
5xdxJ-3u15A:
undetectable		 5xdxA-3u15A:
11.22
5xdxJ-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 8 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.92A 5xdxN-3u15A:
undetectable
5xdxW-3u15A:
undetectable		 5xdxN-3u15A:
11.22
5xdxW-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 6 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.92A 5z86N-3u15A:
undetectable
5z86W-3u15A:
undetectable		 5z86N-3u15A:
11.22
5z86W-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 6 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.94A 5zcoN-3u15A:
undetectable
5zcoW-3u15A:
undetectable		 5zcoN-3u15A:
11.22
5zcoW-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 7 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.84A 6nmfA-3u15A:
undetectable
6nmfJ-3u15A:
undetectable		 6nmfA-3u15A:
11.22
6nmfJ-3u15A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3u15 PROTEIN MDM4
(Homo
sapiens) 		4 / 7 ILE A  36
ARG A  87
MET A 101
LEU A 102
 None
 0.91A 6nmpA-3u15A:
undetectable
6nmpJ-3u15A:
undetectable		 6nmpA-3u15A:
11.22
6nmpJ-3u15A:
24.74