SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u1u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3u1u RNA
POLYMERASE-ASSOCIATE
D PROTEIN RTF1
HOMOLOG
(Homo
sapiens) 		5 / 12 SER A 443
ILE A 405
ASP A 433
ARG A 435
LEU A 428
 UNX  A 511 ( 4.1A)
None
UNX  A 505 ( 4.4A)
None
UNX  A 505 ( 4.6A)
 1.17A 3iv6D-3u1uA:
undetectable		 3iv6D-3u1uA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 3u1u RNA
POLYMERASE-ASSOCIATE
D PROTEIN RTF1
HOMOLOG
(Homo
sapiens) 		5 / 10 GLY A 407
ILE A 405
ALA A 379
THR A 381
GLY A 384
 None
None
None
UNX  A 512 ( 4.0A)
UNX  A 506 ( 4.5A)
 1.11A 6e5zA-3u1uA:
undetectable		 6e5zA-3u1uA:
21.47