SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u1w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 3u1w HYPOTHETICAL
PERIPLASMIC PROTEIN
(Parabacteroides
distasonis) 		4 / 5 GLU A  56
GLY A  57
TYR A  60
ASP A  77
 None
 0.95A 3w9tD-3u1wA:
undetectable		 3w9tD-3u1wA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 3u1w HYPOTHETICAL
PERIPLASMIC PROTEIN
(Parabacteroides
distasonis) 		3 / 3 ASN A 177
ASP A 196
ASN A 197
 None
 0.49A 4agaA-3u1wA:
undetectable		 4agaA-3u1wA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3u1w HYPOTHETICAL
PERIPLASMIC PROTEIN
(Parabacteroides
distasonis) 		4 / 7 ASP A 239
SER A 238
ALA A 235
SER A 234
 None
 1.23A 4lv9A-3u1wA:
undetectable
4lv9B-3u1wA:
undetectable		 4lv9A-3u1wA:
18.99
4lv9B-3u1wA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 3u1w HYPOTHETICAL
PERIPLASMIC PROTEIN
(Parabacteroides
distasonis) 		3 / 3 LYS A 266
ILE A 268
ILE A 276
 None
 0.59A 4y0qA-3u1wA:
undetectable		 4y0qA-3u1wA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 3u1w HYPOTHETICAL
PERIPLASMIC PROTEIN
(Parabacteroides
distasonis) 		4 / 6 TYR A 255
THR A 253
ASP A 271
GLY A 274
 None
 1.06A 5mraA-3u1wA:
undetectable
5mraB-3u1wA:
undetectable		 5mraA-3u1wA:
21.64
5mraB-3u1wA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3u1w HYPOTHETICAL
PERIPLASMIC PROTEIN
(Parabacteroides
distasonis) 		3 / 3 ASP A 158
ASN A 157
ASP A 153
 None
 0.86A 5vopB-3u1wA:
undetectable		 5vopB-3u1wA:
20.45