SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u1x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 3u1x PUTATIVE GLYCOSYL
HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 GLN A 104
LYS A 192
VAL A 196
 None
 0.87A 2jfaB-3u1xA:
undetectable		 2jfaB-3u1xA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 3u1x PUTATIVE GLYCOSYL
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 TRP A 199
LYS A 204
LEU A 190
GLU A 197
 None
 0.93A 3dzgA-3u1xA:
undetectable		 3dzgA-3u1xA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 3u1x PUTATIVE GLYCOSYL
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 VAL A 189
TYR A 121
TRP A 107
GLU A 138
 None
None
None
PGE  A 260 (-3.2A)
 1.28A 3hs4A-3u1xA:
undetectable		 3hs4A-3u1xA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 3u1x PUTATIVE GLYCOSYL
HYDROLASE
(Parabacteroides
distasonis) 		4 / 8 ASP A 143
GLN A 114
PRO A 148
GLN A 162
 None
None
None
PGE  A 260 (-4.2A)
 1.10A 3oyaA-3u1xA:
undetectable		 3oyaA-3u1xA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3u1x PUTATIVE GLYCOSYL
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 PHE A 208
TYR A 171
GLN A 209
TRP A 215
 None
 1.37A 4grqA-3u1xA:
undetectable
4grqC-3u1xA:
undetectable		 4grqA-3u1xA:
16.16
4grqC-3u1xA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3u1x PUTATIVE GLYCOSYL
HYDROLASE
(Parabacteroides
distasonis) 		4 / 8 GLU A 125
GLY A  60
GLY A  61
VAL A  95
 None
 0.60A 5f8yA-3u1xA:
undetectable		 5f8yA-3u1xA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3u1x PUTATIVE GLYCOSYL
HYDROLASE
(Parabacteroides
distasonis) 		4 / 8 GLU A 125
GLY A  60
GLY A  61
VAL A  95
 None
 0.61A 5f8yB-3u1xA:
undetectable		 5f8yB-3u1xA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3u1x PUTATIVE GLYCOSYL
HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 ASN A 185
ASP A 143
GLY A 115
 None
 0.55A 5fctB-3u1xA:
undetectable		 5fctB-3u1xA:
20.47