SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u22'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3u22 PUTATIVE HMUY_LIKE
HEME BINDING PROTEIN
(Bacteroides
vulgatus) 		4 / 7 THR A  65
LEU A 197
VAL A 167
GLU A 160
 SO4  A 309 ( 4.9A)
None
None
None
 1.13A 5tudA-3u22A:
undetectable		 5tudA-3u22A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3u22 PUTATIVE HMUY_LIKE
HEME BINDING PROTEIN
(Bacteroides
vulgatus) 		4 / 5 ILE A  92
PHE A  69
ARG A 196
THR A 211
 None
None
None
GOL  A 315 ( 4.4A)
 1.24A 5z84N-3u22A:
undetectable
5z84W-3u22A:
undetectable		 5z84N-3u22A:
17.72
5z84W-3u22A:
13.86