SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u27'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 3u27 MICROCOMPARTMENTS
PROTEIN
(Leptotrichia
buccalis) 		4 / 5 ASP C  52
GLU C 143
THR C 138
LEU C 135
 None
 1.14A 1u18B-3u27C:
undetectable		 1u18B-3u27C:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3u27 MICROCOMPARTMENTS
PROTEIN
(Leptotrichia
buccalis) 		4 / 4 ASP C 117
ASP C 119
ASP C 212
GLY C   3
 None
 1.20A 2igtC-3u27C:
undetectable		 2igtC-3u27C:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 3u27 MICROCOMPARTMENTS
PROTEIN
(Leptotrichia
buccalis) 		4 / 5 ASN C  18
ALA C  93
LEU C  99
GLY C  37
 None
 0.96A 3dl9A-3u27C:
undetectable		 3dl9A-3u27C:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 3u27 MICROCOMPARTMENTS
PROTEIN
(Leptotrichia
buccalis) 		5 / 9 ALA C  50
GLY C  65
ILE C  86
VAL C  10
ILE C 106
 None
 1.07A 3nu4A-3u27C:
undetectable		 3nu4A-3u27C:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3u27 MICROCOMPARTMENTS
PROTEIN
(Leptotrichia
buccalis) 		4 / 4 ALA C 195
ALA C 198
ALA C 199
ALA C 202
 None
 0.11A 4oadA-3u27C:
undetectable		 4oadA-3u27C:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3u27 MICROCOMPARTMENTS
PROTEIN
(Leptotrichia
buccalis) 		4 / 4 ALA C 195
ALA C 198
ALA C 199
ALA C 202
 None
 0.09A 4oaeA-3u27C:
1.5		 4oaeA-3u27C:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3u27 MICROCOMPARTMENTS
PROTEIN
(Leptotrichia
buccalis) 		5 / 12 ASP C  44
SER C 180
THR C 138
ALA C 174
TYR C 149
 GOL  C 302 ( 2.9A)
GOL  C 303 (-4.3A)
None
None
None
 1.41A 4u15B-3u27C:
undetectable		 4u15B-3u27C:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 3u27 MICROCOMPARTMENTS
PROTEIN
(Leptotrichia
buccalis) 		4 / 8 GLY C  71
GLU C  82
TYR C  48
ASP C  45
 GOL  C 302 ( 4.5A)
GOL  C 302 (-2.9A)
GOL  C 303 (-4.7A)
GOL  C 303 ( 3.1A)
 0.92A 5gqbA-3u27C:
undetectable		 5gqbA-3u27C:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 3u27 MICROCOMPARTMENTS
PROTEIN
(Leptotrichia
buccalis) 		5 / 12 PHE C  68
ALA C 101
LEU C  87
ILE C  86
LEU C  39
 None
 1.10A 6aybA-3u27C:
undetectable		 6aybA-3u27C:
19.76