SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u2p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		4 / 8 PHE A  51
LEU A  24
LEU A  72
LEU A  74
 None
 0.85A 2bfpA-3u2pA:
undetectable		 2bfpA-3u2pA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		4 / 8 PHE A  51
LEU A  24
LEU A  72
LEU A  74
 None
 0.85A 2bfpB-3u2pA:
undetectable		 2bfpB-3u2pA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		4 / 7 GLY A 313
THR A 314
PHE A 331
PHE A 367
 None
 1.02A 2qx4A-3u2pA:
undetectable
2qx4B-3u2pA:
undetectable		 2qx4A-3u2pA:
17.60
2qx4B-3u2pA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		5 / 12 LEU A 395
VAL A 366
ASP A 388
LEU A 377
LEU A 409
 None
 1.27A 3cjtK-3u2pA:
undetectable		 3cjtK-3u2pA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		5 / 11 LEU A 111
ILE A  40
VAL A  62
LEU A  38
VAL A  34
 None
 1.06A 3w67A-3u2pA:
undetectable		 3w67A-3u2pA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		5 / 12 ILE A 398
PHE A 422
ILE A 433
ILE A 435
LEU A 441
 None
 1.07A 3w67B-3u2pA:
undetectable		 3w67B-3u2pA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		5 / 12 LEU A 111
ILE A  43
ILE A  40
VAL A  62
LEU A  38
 None
 1.10A 3w67B-3u2pA:
undetectable		 3w67B-3u2pA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		5 / 12 LEU A 111
ILE A  40
VAL A  62
LEU A  38
VAL A  34
 None
 0.99A 3w68A-3u2pA:
undetectable		 3w68A-3u2pA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		5 / 12 LEU A 111
ILE A  40
VAL A  62
LEU A  38
VAL A  34
 None
 0.98A 3w68D-3u2pA:
undetectable		 3w68D-3u2pA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		4 / 6 GLY A  82
ASN A 119
LEU A  85
GLU A   8
 None
 0.90A 3zqtA-3u2pA:
undetectable		 3zqtA-3u2pA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		4 / 8 VAL A 122
TRP A 138
ILE A 141
LEU A 111
 None
 0.94A 4jq1B-3u2pA:
undetectable		 4jq1B-3u2pA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		5 / 10 VAL A 122
TRP A 138
ILE A 141
LEU A  72
LEU A 109
 None
 1.27A 4jtqA-3u2pA:
undetectable		 4jtqA-3u2pA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		5 / 10 VAL A 122
TRP A 138
ILE A 141
LEU A  72
LEU A 111
 None
 1.42A 4jtqA-3u2pA:
undetectable		 4jtqA-3u2pA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		5 / 12 GLY A 399
ILE A 337
ASN A 338
SER A 408
ASN A 340
 None
 1.29A 4obwC-3u2pA:
undetectable		 4obwC-3u2pA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		3 / 3 PHE A  69
THR A   7
LEU A  52
 None
 0.60A 4qztA-3u2pA:
undetectable		 4qztA-3u2pA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		4 / 4 ILE A 379
ASN A 378
ILE A 312
VAL A 323
 None
 0.98A 4uy87-3u2pA:
undetectable		 4uy87-3u2pA:
4.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 138
ILE A 141
LEU A  72
 None
 0.96A 4xo7B-3u2pA:
undetectable		 4xo7B-3u2pA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 138
ILE A 141
LEU A  74
 None
 1.08A 4xo7B-3u2pA:
undetectable		 4xo7B-3u2pA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		5 / 12 VAL A 391
ILE A 447
ILE A 417
LEU A 441
ILE A 435
 None
 0.94A 5mueA-3u2pA:
undetectable		 5mueA-3u2pA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		5 / 12 VAL A 391
ILE A 447
ILE A 417
LEU A 441
ILE A 435
 None
 0.99A 5mugA-3u2pA:
undetectable		 5mugA-3u2pA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		4 / 5 ILE A 379
PHE A 389
ASN A 470
TYR A 444
 None
None
NAG  A1005 (-1.8A)
None
 1.10A 6a93B-3u2pA:
undetectable		 6a93B-3u2pA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
(Homo
sapiens) 		3 / 3 GLY A 399
THR A 397
GLU A 427
 None
 0.62A 6b58A-3u2pA:
undetectable		 6b58A-3u2pA:
21.09