SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u3g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.77A 1dhiA-3u3gD:
undetectable		 1dhiA-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 11 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.70A 1dhiB-3u3gD:
undetectable		 1dhiB-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.72A 1dhjA-3u3gD:
undetectable		 1dhjA-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.70A 1dhjB-3u3gD:
undetectable		 1dhjB-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.74A 1draB-3u3gD:
undetectable		 1draB-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.78A 1drbA-3u3gD:
undetectable		 1drbA-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.74A 1drbB-3u3gD:
undetectable		 1drbB-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.80A 1ra2A-3u3gD:
undetectable		 1ra2A-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.83A 1ra3A-3u3gD:
undetectable		 1ra3A-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.82A 1ra8A-3u3gD:
undetectable		 1ra8A-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.78A 1rb2A-3u3gD:
undetectable		 1rb2A-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.74A 1rb2B-3u3gD:
undetectable		 1rb2B-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.72A 1rb3B-3u3gD:
undetectable		 1rb3B-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.81A 1rd7A-3u3gD:
undetectable		 1rd7A-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.84A 1rd7B-3u3gD:
undetectable		 1rd7B-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.77A 1re7B-3u3gD:
undetectable		 1re7B-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.80A 1rx2A-3u3gD:
undetectable		 1rx2A-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.78A 1rx7A-3u3gD:
undetectable		 1rx7A-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2003_1
(SERUM ALBUMIN)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 10 ARG D 110
LEU D  60
ILE D  25
HIS D  34
GLY D  22
 None
 1.37A 2bxqA-3u3gD:
undetectable		 2bxqA-3u3gD:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.79A 2d0kA-3u3gD:
undetectable		 2d0kA-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_B_FOLB2161_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.80A 2d0kB-3u3gD:
undetectable		 2d0kB-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.75A 2drcB-3u3gD:
undetectable		 2drcB-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		4 / 7 VAL D  23
SER D  36
ARG D  55
LEU D  57
 None
 1.09A 2f78A-3u3gD:
undetectable		 2f78A-3u3gD:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		4 / 7 VAL D  23
SER D  36
ARG D  55
LEU D  57
 None
 1.16A 2f78B-3u3gD:
undetectable		 2f78B-3u3gD:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		4 / 6 VAL D  23
SER D  36
ARG D  55
LEU D  60
 None
 1.30A 2f8dA-3u3gD:
undetectable		 2f8dA-3u3gD:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.74A 3drcB-3u3gD:
undetectable		 3drcB-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.81A 3tq9A-3u3gD:
undetectable		 3tq9A-3u3gD:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_B_MTXB162_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.75A 4dfrB-3u3gD:
undetectable		 4dfrB-3u3gD:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.74A 4fhbA-3u3gD:
undetectable		 4fhbA-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		4 / 8 MET D  76
LEU D 114
THR D   8
VAL D  23
 None
 0.91A 4ik6B-3u3gD:
undetectable		 4ik6B-3u3gD:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P66_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 11 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.79A 4p66A-3u3gD:
undetectable		 4p66A-3u3gD:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 LEU D 139
GLU D  42
GLY D  17
ALA D  12
ASN D  45
 None
 1.28A 4pclB-3u3gD:
undetectable		 4pclB-3u3gD:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.78A 4x5gB-3u3gD:
undetectable		 4x5gB-3u3gD:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.82A 4x5iA-3u3gD:
undetectable		 4x5iA-3u3gD:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.77A 5eajA-3u3gD:
undetectable		 5eajA-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		4 / 8 ILE D  25
LEU D  57
ILE D   4
THR D   8
 None
 0.76A 5uihA-3u3gD:
undetectable		 5uihA-3u3gD:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.76A 5ujxA-3u3gD:
undetectable		 5ujxA-3u3gD:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.87A 5z6jA-3u3gD:
undetectable		 5z6jA-3u3gD:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 0.87A 5z6kA-3u3gD:
undetectable		 5z6kA-3u3gD:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6M_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3u3g RIBONUCLEASE H
(uncultured
organism) 		5 / 11 ILE D  25
LEU D  57
LEU D  67
ILE D   4
THR D   8
 None
 1.03A 5z6mA-3u3gD:
undetectable		 5z6mA-3u3gD:
21.15