SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u3l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 3u3l TABLYSIN 15
(Tabanus
yao) 		4 / 6 PHE C 188
GLU C 155
LEU C 156
VAL C  50
 None
None
None
PLM  C 233 ( 4.1A)
 1.06A 1hk1A-3u3lC:
undetectable		 1hk1A-3u3lC:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 3u3l TABLYSIN 15
(Tabanus
yao) 		4 / 7 PHE C 188
GLU C 155
LEU C 156
VAL C  50
 None
None
None
PLM  C 233 ( 4.1A)
 1.04A 1hk3A-3u3lC:
undetectable		 1hk3A-3u3lC:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3u3l TABLYSIN 15
(Tabanus
yao) 		5 / 12 LEU C 121
ALA C 180
ALA C 182
TYR C 110
ARG C  33
 None
 1.17A 2japD-3u3lC:
undetectable		 2japD-3u3lC:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3u3l TABLYSIN 15
(Tabanus
yao) 		4 / 6 LEU C 219
LYS C  56
ALA C  64
PRO C 205
 None
 1.30A 3gv1A-3u3lC:
undetectable
3gv1C-3u3lC:
undetectable		 3gv1A-3u3lC:
19.23
3gv1C-3u3lC:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 3u3l TABLYSIN 15
(Tabanus
yao) 		3 / 3 GLY C  89
GLN C 105
LYS C 109
 None
 0.52A 5imsB-3u3lC:
undetectable		 5imsB-3u3lC:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 3u3l TABLYSIN 15
(Tabanus
yao) 		4 / 7 GLN C 191
GLY C 104
PHE C 188
SER C 161
 None
 1.03A 6hu9S-3u3lC:
undetectable
6hu9q-3u3lC:
undetectable		 6hu9S-3u3lC:
15.96
6hu9q-3u3lC:
19.63