SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u3p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3u3p TUMOR NECROSIS
FACTOR RECEPTOR
SUPERFAMILY MEMBER
21
(Homo
sapiens) 		4 / 7 SER A 177
LYS A 187
SER A 181
VAL A 179
 None
 1.41A 2j9cA-3u3pA:
undetectable
2j9cB-3u3pA:
undetectable
2j9cC-3u3pA:
undetectable		 2j9cA-3u3pA:
17.72
2j9cB-3u3pA:
17.72
2j9cC-3u3pA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3u3p TUMOR NECROSIS
FACTOR RECEPTOR
SUPERFAMILY MEMBER
21
(Homo
sapiens) 		4 / 7 SER A 181
VAL A 183
SER A 177
LYS A 187
 None
 1.30A 2j9cA-3u3pA:
undetectable
2j9cB-3u3pA:
undetectable
2j9cC-3u3pA:
undetectable		 2j9cA-3u3pA:
17.72
2j9cB-3u3pA:
17.72
2j9cC-3u3pA:
17.72